Increased Expression of miR-155p5 in Amygdala of Children With Autism Spectrum Disorder / Khulood Abdullah ALMEHMADI in Autism Research, 13-1 (January 2020)  

Public ISBD [article]  inAutism Research > 13-1 (January 2020) . - p.18-23 Titre : Increased Expression of miR-155p5 in Amygdala of Children With Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Khulood Abdullah ALMEHMADI, Auteur ; Irene TSILIONI, Auteur ; Theoharis C. THEOHARIDES, Auteur Article en page(s) : p.18-23 Langues : Anglais (eng) Mots-clés : Mir-155  autism spectrum disorder  brain  microRNAs  neuroinflammation Index. décimale : PER Périodiques Résumé : MiR-155p5 is a pro-inflammatory microRNA reported to be involved in several neurol-inflammatory diseases. Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by impaired social interactions and communication, as well as stereotypic movements. Inflammation of the brain due to activation of microglia has been reported in ASD. We investigated miR-155p5 gene expression in postmortem human brain tissues [amygdala and dorsolateral prefrontal cortex regions (DLPFC)]. There was significant increase of miR-155p5 in amygdala (P En ligne : http://dx.doi.org/10.1002/aur.2205 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=415 [article] Increased Expression of miR-155p5 in Amygdala of Children With Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Khulood Abdullah ALMEHMADI, Auteur ; Irene TSILIONI, Auteur ; Theoharis C. THEOHARIDES, Auteur . - p.18-23. Langues : Anglais (eng) in Autism Research > 13-1 (January 2020) . - p.18-23 Mots-clés : Mir-155  autism spectrum disorder  brain  microRNAs  neuroinflammation Index. décimale : PER Périodiques Résumé : MiR-155p5 is a pro-inflammatory microRNA reported to be involved in several neurol-inflammatory diseases. Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by impaired social interactions and communication, as well as stereotypic movements. Inflammation of the brain due to activation of microglia has been reported in ASD. We investigated miR-155p5 gene expression in postmortem human brain tissues [amygdala and dorsolateral prefrontal cortex regions (DLPFC)]. There was significant increase of miR-155p5 in amygdala (P En ligne : http://dx.doi.org/10.1002/aur.2205 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=415

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