Trajectories of Change in the Behavioral and Health Phenotype of Adolescents and Adults with Fragile X Syndrome and Intellectual Disability: Longitudinal Trends Over a Decade / Lauren V. USHER in Journal of Autism and Developmental Disorders, 50-8 (August 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-8 (August 2020) . - p.2779-2792 Titre : Trajectories of Change in the Behavioral and Health Phenotype of Adolescents and Adults with Fragile X Syndrome and Intellectual Disability: Longitudinal Trends Over a Decade Type de document : Texte imprimé et/ou numérique Auteurs : Lauren V. USHER, Auteur ; Leann S. DAWALT, Auteur ; Jinkuk HONG, Auteur ; Jan S GREENBERG, Auteur ; Marsha R. MAILICK, Auteur Article en page(s) : p.2779-2792 Langues : Anglais (eng) Mots-clés : Adolescents  Adults  Behavioral phenotype  Fragile X syndrome  Health phenotype Index. décimale : PER Périodiques Résumé : This study examined trajectories of daily living skills, behavior problems, body mass index (BMI), and health conditions spanning nearly a decade in adolescents and adults with fragile X syndrome (N?=?134; age range at study end?=?19-49 years), examining influences of sex and autism spectrum disorder (ASD) symptoms. Hierarchical linear modeling revealed early increases in daily living skills, with decreases at older ages. Behavior problems became less severe over time, with some increases at older ages. Individuals gained weight and had increasing health problems over time. Fewer ASD symptoms were associated with greater daily living skills and fewer behavior problems at study start. This study offers some of the first prospective quantitative analyses of behavioral and health life course trajectories in FXS. En ligne : http://dx.doi.org/10.1007/s10803-020-04367-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=428 [article] Trajectories of Change in the Behavioral and Health Phenotype of Adolescents and Adults with Fragile X Syndrome and Intellectual Disability: Longitudinal Trends Over a Decade [Texte imprimé et/ou numérique] / Lauren V. USHER, Auteur ; Leann S. DAWALT, Auteur ; Jinkuk HONG, Auteur ; Jan S GREENBERG, Auteur ; Marsha R. MAILICK, Auteur . - p.2779-2792. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-8 (August 2020) . - p.2779-2792 Mots-clés : Adolescents  Adults  Behavioral phenotype  Fragile X syndrome  Health phenotype Index. décimale : PER Périodiques Résumé : This study examined trajectories of daily living skills, behavior problems, body mass index (BMI), and health conditions spanning nearly a decade in adolescents and adults with fragile X syndrome (N?=?134; age range at study end?=?19-49 years), examining influences of sex and autism spectrum disorder (ASD) symptoms. Hierarchical linear modeling revealed early increases in daily living skills, with decreases at older ages. Behavior problems became less severe over time, with some increases at older ages. Individuals gained weight and had increasing health problems over time. Fewer ASD symptoms were associated with greater daily living skills and fewer behavior problems at study start. This study offers some of the first prospective quantitative analyses of behavioral and health life course trajectories in FXS. En ligne : http://dx.doi.org/10.1007/s10803-020-04367-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=428

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