CSF levels of lactate and hydroxybutyrate dehydrogenase as indicators of neurological sequelae after neonatal brain damage / Bernard DALENS in Developmental Medicine & Child Neurology, 23-2 (April 1981)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > 23-2 (April 1981) . - p.228-233 Titre : CSF levels of lactate and hydroxybutyrate dehydrogenase as indicators of neurological sequelae after neonatal brain damage Type de document : Texte imprimé et/ou numérique Auteurs : Bernard DALENS, Auteur ; Jean-Louis VIALLARD, Auteur ; Elie-Jean REYNAUD, Auteur ; Bernard DASTUGE, Auteur Année de publication : 1981 Article en page(s) : p.228-233 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : A prospective study was made of levels of lactate and hydroxybutyrate dehydrogenase in the blood and cerebrospinal fluid of 57 term neonates, in relation to the time elapsed since delivery, neonatal examinations (Apgar score, neurological symptoms and EEG findings) and psychomotor outcome at one year of age. Serum determinations revealed no significant relationship with clinical assessments. CSF measurements showed significant differences near to the time of delivery between the normal and handicapped groups at age one, which supports the hypothesis of a causal link between neonatal brain damage and CSF enzyme levels. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] CSF levels of lactate and hydroxybutyrate dehydrogenase as indicators of neurological sequelae after neonatal brain damage [Texte imprimé et/ou numérique] / Bernard DALENS, Auteur ; Jean-Louis VIALLARD, Auteur ; Elie-Jean REYNAUD, Auteur ; Bernard DASTUGE, Auteur . - 1981 . - p.228-233. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > 23-2 (April 1981) . - p.228-233 Index. décimale : PER Périodiques Résumé : A prospective study was made of levels of lactate and hydroxybutyrate dehydrogenase in the blood and cerebrospinal fluid of 57 term neonates, in relation to the time elapsed since delivery, neonatal examinations (Apgar score, neurological symptoms and EEG findings) and psychomotor outcome at one year of age. Serum determinations revealed no significant relationship with clinical assessments. CSF measurements showed significant differences near to the time of delivery between the normal and handicapped groups at age one, which supports the hypothesis of a causal link between neonatal brain damage and CSF enzyme levels. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

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