Analysis of 100 infant deaths with intraventricular hemorrhage: brain weights and risk factors / Gabrielle M. DE COURTEN in Developmental Medicine & Child Neurology, 23-3 (June 1981)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > 23-3 (June 1981) . - p.287-295 Titre : Analysis of 100 infant deaths with intraventricular hemorrhage: brain weights and risk factors Type de document : Texte imprimé et/ou numérique Auteurs : Gabrielle M. DE COURTEN, Auteur ; Th. RABINOWICZ, Auteur Année de publication : 1981 Article en page(s) : p.287-295 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Because the lowering of brain-tissue pressure is associated with a loss in brain weight, the brain weights of 100 infants with intraventricular hemorrhage were compared with those of 100 control infants. After the 30th week of gestation the brain weight of infants with intraventricular hemorrhage were lower than those of the controls. This finding supports the authors' hypothesis of a causal relationship between brain shrinkage and intraventricular hemorrhage. Of 13 other risk factors investigated, only prematurity could be related directly to the occurrence of intraventricular hemorrhage. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=520 [article] Analysis of 100 infant deaths with intraventricular hemorrhage: brain weights and risk factors [Texte imprimé et/ou numérique] / Gabrielle M. DE COURTEN, Auteur ; Th. RABINOWICZ, Auteur . - 1981 . - p.287-295. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > 23-3 (June 1981) . - p.287-295 Index. décimale : PER Périodiques Résumé : Because the lowering of brain-tissue pressure is associated with a loss in brain weight, the brain weights of 100 infants with intraventricular hemorrhage were compared with those of 100 control infants. After the 30th week of gestation the brain weight of infants with intraventricular hemorrhage were lower than those of the controls. This finding supports the authors' hypothesis of a causal relationship between brain shrinkage and intraventricular hemorrhage. Of 13 other risk factors investigated, only prematurity could be related directly to the occurrence of intraventricular hemorrhage. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=520

Intraventricular hemorrhage in premature infants: reappraisal and new hypothesis / Gabrielle M. DE COURTEN in Developmental Medicine & Child Neurology, 23-3 (June 1981)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > 23-3 (June 1981) . - p.389-403 Titre : Intraventricular hemorrhage in premature infants: reappraisal and new hypothesis Type de document : Texte imprimé et/ou numérique Auteurs : Gabrielle M. DE COURTEN, Auteur ; Th. RABINOWICZ, Auteur Année de publication : 1981 Article en page(s) : p.389-403 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Germinal matrix hemorrhage leading to intraventricular hemorrhage results from an excessive pressure gradient between the blood-vessel lumen and the surrounding brain tissue. This gradient may be caused by increased intravascular pressure or--as this paper hypothesises--by decreased tissue pressure. Brain-tissue pressure depends on water content, and it decreases when water moves out of the brain, as occurs in conditions associated with dehydration, plasma hyperosmolality or hypotension. Such conditions occur frequently in premature infants, which may explain why intraventricular hemorrhage develops with a delay after birth. Its coincidence in time with postnatal head-shrinkage and its association with plasma hyperosmolality, hyperosmolar alkali therapy and hypotension strengthen the hypothesis of a cause and effect relationship between reduced cerebral tissue pressure and intraventricular hemorrhage. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=521 [article] Intraventricular hemorrhage in premature infants: reappraisal and new hypothesis [Texte imprimé et/ou numérique] / Gabrielle M. DE COURTEN, Auteur ; Th. RABINOWICZ, Auteur . - 1981 . - p.389-403. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > 23-3 (June 1981) . - p.389-403 Index. décimale : PER Périodiques Résumé : Germinal matrix hemorrhage leading to intraventricular hemorrhage results from an excessive pressure gradient between the blood-vessel lumen and the surrounding brain tissue. This gradient may be caused by increased intravascular pressure or--as this paper hypothesises--by decreased tissue pressure. Brain-tissue pressure depends on water content, and it decreases when water moves out of the brain, as occurs in conditions associated with dehydration, plasma hyperosmolality or hypotension. Such conditions occur frequently in premature infants, which may explain why intraventricular hemorrhage develops with a delay after birth. Its coincidence in time with postnatal head-shrinkage and its association with plasma hyperosmolality, hyperosmolar alkali therapy and hypotension strengthen the hypothesis of a cause and effect relationship between reduced cerebral tissue pressure and intraventricular hemorrhage. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=521

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