Altered Cerebellum Spontaneous Activity in Juvenile Autism Spectrum Disorders Associated with Clinical Traits / Jinglun LI in Journal of Autism and Developmental Disorders, 52-6 (June 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-6 (June 2022) . - p.2497-2504 Titre : Altered Cerebellum Spontaneous Activity in Juvenile Autism Spectrum Disorders Associated with Clinical Traits Type de document : Texte imprimé et/ou numérique Auteurs : Jinglun LI, Auteur ; Xiu CHEN, Auteur ; Ruwen ZHENG, Auteur ; Ai CHEN, Auteur ; Yan ZHOU, Auteur ; Jianghai RUAN, Auteur Article en page(s) : p.2497-2504 Langues : Anglais (eng) Mots-clés : Amplitude of low-frequency fluctuations  Autism spectrum disorders  Cerebellum  Functional magnetic resonance imaging Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a neurodevelopmental disorder. The associations between the cerebellum and clinical traits remain unclear. We performed amplitude of low-frequency fluctuation (ALFF) analysis to explore the associations between spontaneous brain activity and clinical traits. 361 juvenile ASD patients were included from the ABIDEII database. In the ASD group, the mean ALFF values of cerebellum 4 5 were correlated with SRS awareness and communication. The mean ALFF values of cerebellum 6 and vermis 4 5 were both positively correlated with SRS total, awareness, communication, and motivation. In contrast, the mean ALFF values of vermis 1 2 were negatively correlated with SRS total, awareness, and mannerisms. Our study suggests a role of the cerebellum in functional impairments in ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-05167-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474 [article] Altered Cerebellum Spontaneous Activity in Juvenile Autism Spectrum Disorders Associated with Clinical Traits [Texte imprimé et/ou numérique] / Jinglun LI, Auteur ; Xiu CHEN, Auteur ; Ruwen ZHENG, Auteur ; Ai CHEN, Auteur ; Yan ZHOU, Auteur ; Jianghai RUAN, Auteur . - p.2497-2504. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-6 (June 2022) . - p.2497-2504 Mots-clés : Amplitude of low-frequency fluctuations  Autism spectrum disorders  Cerebellum  Functional magnetic resonance imaging Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a neurodevelopmental disorder. The associations between the cerebellum and clinical traits remain unclear. We performed amplitude of low-frequency fluctuation (ALFF) analysis to explore the associations between spontaneous brain activity and clinical traits. 361 juvenile ASD patients were included from the ABIDEII database. In the ASD group, the mean ALFF values of cerebellum 4 5 were correlated with SRS awareness and communication. The mean ALFF values of cerebellum 6 and vermis 4 5 were both positively correlated with SRS total, awareness, communication, and motivation. In contrast, the mean ALFF values of vermis 1 2 were negatively correlated with SRS total, awareness, and mannerisms. Our study suggests a role of the cerebellum in functional impairments in ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-05167-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474

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