Obstetric and Parental Psychiatric Variables as Potential Predictors of Autism Severity / Anna E. WALLACE in Journal of Autism and Developmental Disorders, 38-8 (September 2008)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 38-8 (September 2008) . - p.1542-1554 Titre : Obstetric and Parental Psychiatric Variables as Potential Predictors of Autism Severity Type de document : Texte imprimé et/ou numérique Auteurs : Anna E. WALLACE, Auteur ; George M. ANDERSON, Auteur ; Robert DUBROW, Auteur Année de publication : 2008 Article en page(s) : p.1542-1554 Langues : Anglais (eng) Mots-clés : Autism Preeclampsia Psychiatric Obstetric Hypertension Depression Index. décimale : PER Périodiques Résumé : Associations between obstetric and parental psychiatric variables and subjects’ Autism Diagnostic Interview-Revised (ADI-R) and Autism Diagnostic Observation Schedule (ADOS) domain scores were examined using linear mixed effects models. Data for the 228 families studied were provided by the Autism Genetic Resource Exchange. Hypertension (P = 0.002), preeclampsia (P = 0.021) and generalized edema (P = 0.011) were associated with higher ADI-R communication scores. Hypertension (P = 0.011), albuminuria (P = 0.039) and generalized edema (P = 0.009) were associated with higher ADI-R repetitive behaviors scores. Parent depression was associated with higher ADI-R repetitive behaviors scores (P = 0.005), and parent anxiety with lower ADOS social/communication composite scores (P = 0.025). The associations between hypertension-related obstetric conditions and autistic severity warrant further investigation and raise intriguing questions regarding potential causal and modifying factors in autism. En ligne : http://dx.doi.org/10.1007/s10803-007-0536-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=539 [article] Obstetric and Parental Psychiatric Variables as Potential Predictors of Autism Severity [Texte imprimé et/ou numérique] / Anna E. WALLACE, Auteur ; George M. ANDERSON, Auteur ; Robert DUBROW, Auteur . - 2008 . - p.1542-1554. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 38-8 (September 2008) . - p.1542-1554 Mots-clés : Autism Preeclampsia Psychiatric Obstetric Hypertension Depression Index. décimale : PER Périodiques Résumé : Associations between obstetric and parental psychiatric variables and subjects’ Autism Diagnostic Interview-Revised (ADI-R) and Autism Diagnostic Observation Schedule (ADOS) domain scores were examined using linear mixed effects models. Data for the 228 families studied were provided by the Autism Genetic Resource Exchange. Hypertension (P = 0.002), preeclampsia (P = 0.021) and generalized edema (P = 0.011) were associated with higher ADI-R communication scores. Hypertension (P = 0.011), albuminuria (P = 0.039) and generalized edema (P = 0.009) were associated with higher ADI-R repetitive behaviors scores. Parent depression was associated with higher ADI-R repetitive behaviors scores (P = 0.005), and parent anxiety with lower ADOS social/communication composite scores (P = 0.025). The associations between hypertension-related obstetric conditions and autistic severity warrant further investigation and raise intriguing questions regarding potential causal and modifying factors in autism. En ligne : http://dx.doi.org/10.1007/s10803-007-0536-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=539

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