Evaluation of retinal nerve fiber layer thickness in children with autism spectrum disorders / Abdullah BOZKURT in Research in Autism Spectrum Disorders, 98 (October 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 98 (October 2022) . - 102050 Titre : Evaluation of retinal nerve fiber layer thickness in children with autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Abdullah BOZKURT, Auteur ; Gokçe Nur SAY, Auteur ; Berkan SAHIN, Auteur ; Miraç Baris USTA, Auteur ; Merve KALYONCU, Auteur ; Nurullah KOCAK, Auteur ; Osmanli CANSU COBANOGLU, Auteur Article en page(s) : 102050 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Retinal nerve fiber layer thickness  Optical coherence tomography Index. décimale : PER Périodiques Résumé : Background The study compared retinal nerve fiber layer (RNFL) thickness, macular thickness, and macular volume of children with autism spectrum disorder (ASD) to those of healthy control group and correlated the RNFL thickness with symptom severity in children with ASD. Method Forty children between the ages of 7 and 12 with normal intelligence levels and who were diagnosed with ASD as per DSM-5 were included in the ASD group. The control group consisted of healthy children, who were matched with subjects in the ASD group in terms of age and gender. The Autism Behavior Checklist (ABC) and Childhood Autism Rating Scale (CARS) were used to evaluate the severity of the disease in the cases diagnosed with ASD. The RNFL, macular thickness, and macular volume of all participants were measured optical coherence tomography (OCT). Results The temporal, temporal superior, nasal superior, temporal inferior, and global RNFL thicknesses were significantly lower in the ASD group than in the control group. There was no correlation between the RNFL thickness and ASD symptom severity. The macular thickness and volume were not significantly different between the groups. Conclusion Our data suggest that lower RNFL thickness may relate to atypical brain development in the ASD, and this can be measured in the retina. En ligne : https://doi.org/10.1016/j.rasd.2022.102050 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490 [article] Evaluation of retinal nerve fiber layer thickness in children with autism spectrum disorders [Texte imprimé et/ou numérique] / Abdullah BOZKURT, Auteur ; Gokçe Nur SAY, Auteur ; Berkan SAHIN, Auteur ; Miraç Baris USTA, Auteur ; Merve KALYONCU, Auteur ; Nurullah KOCAK, Auteur ; Osmanli CANSU COBANOGLU, Auteur . - 102050. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 98 (October 2022) . - 102050 Mots-clés : Autism spectrum disorders  Retinal nerve fiber layer thickness  Optical coherence tomography Index. décimale : PER Périodiques Résumé : Background The study compared retinal nerve fiber layer (RNFL) thickness, macular thickness, and macular volume of children with autism spectrum disorder (ASD) to those of healthy control group and correlated the RNFL thickness with symptom severity in children with ASD. Method Forty children between the ages of 7 and 12 with normal intelligence levels and who were diagnosed with ASD as per DSM-5 were included in the ASD group. The control group consisted of healthy children, who were matched with subjects in the ASD group in terms of age and gender. The Autism Behavior Checklist (ABC) and Childhood Autism Rating Scale (CARS) were used to evaluate the severity of the disease in the cases diagnosed with ASD. The RNFL, macular thickness, and macular volume of all participants were measured optical coherence tomography (OCT). Results The temporal, temporal superior, nasal superior, temporal inferior, and global RNFL thicknesses were significantly lower in the ASD group than in the control group. There was no correlation between the RNFL thickness and ASD symptom severity. The macular thickness and volume were not significantly different between the groups. Conclusion Our data suggest that lower RNFL thickness may relate to atypical brain development in the ASD, and this can be measured in the retina. En ligne : https://doi.org/10.1016/j.rasd.2022.102050 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490

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