A population-based case-control study of anencephalus and spina bifida in a low-risk area / Marc A. STRASSBURG in Developmental Medicine & Child Neurology, 25-5 (October 1983)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > 25-5 (October 1983) . - p.632-641 Titre : A population-based case-control study of anencephalus and spina bifida in a low-risk area Type de document : Texte imprimé et/ou numérique Auteurs : Marc A. STRASSBURG, Auteur ; Lowell E. SEVER, Auteur ; Sander GREENLAND, Auteur ; Lawrence D. PORTIGAL, Auteur Année de publication : 1983 Article en page(s) : p.632-641 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : For the period 1973 to 1977, a total of 536 cases of anencephalus and spina bifida were ascertained in Los Angeles County, California, a low-risk area, and compared with a 2 per cent random sample of all live births in the county. Women with Spanish surnames had an elevated risk for anencephalus and to a lesser extent for spina bifida; Blacks were at lowest risk, especially for spina bifida. The occurrence of a previous fetal death was a strong risk factor for anencephalus but there was no association between socio-economic status and either of the defects. Advanced maternal age was a stronger risk factor for spina bifida than for anencephalus but, as in other studies in low-risk areas, no increased risk was observed among teenage mothers. Paternal age did not show any independent association after controlling for mother's age. Finally, the association of high birth-order with the birth defects was weakened greatly after simultaneous adjustment for age and ethnicity. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=569 [article] A population-based case-control study of anencephalus and spina bifida in a low-risk area [Texte imprimé et/ou numérique] / Marc A. STRASSBURG, Auteur ; Lowell E. SEVER, Auteur ; Sander GREENLAND, Auteur ; Lawrence D. PORTIGAL, Auteur . - 1983 . - p.632-641. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > 25-5 (October 1983) . - p.632-641 Index. décimale : PER Périodiques Résumé : For the period 1973 to 1977, a total of 536 cases of anencephalus and spina bifida were ascertained in Los Angeles County, California, a low-risk area, and compared with a 2 per cent random sample of all live births in the county. Women with Spanish surnames had an elevated risk for anencephalus and to a lesser extent for spina bifida; Blacks were at lowest risk, especially for spina bifida. The occurrence of a previous fetal death was a strong risk factor for anencephalus but there was no association between socio-economic status and either of the defects. Advanced maternal age was a stronger risk factor for spina bifida than for anencephalus but, as in other studies in low-risk areas, no increased risk was observed among teenage mothers. Paternal age did not show any independent association after controlling for mother's age. Finally, the association of high birth-order with the birth defects was weakened greatly after simultaneous adjustment for age and ethnicity. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=569

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