[article]
| Titre : |
Autism and immune factors: A comprehensive review |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Kimberly A. STIGLER, Auteur ; Thayne L. SWEETEN, Auteur ; Christopher J. MCDOUGLE, Auteur ; David J. POSEY, Auteur |
| Année de publication : |
2009 |
| Article en page(s) : |
p.840-860 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Autism Immune Infection Immunogenetics Cytokines Gastrointestinal Autoimmune |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Cases of autistic disorder (autism) have frequently been reported in association with congenital rubella and other infections. These observations stimulated further investigation into markers of immune function in autism. Postinfectious and autoimmune mechanisms of pathophysiology have been proposed. This review comprehensively addresses immune findings to date, including the role of viruses, neuroimmune factors, cellular and humoral immunity, immunogenetics, and immunotherapy in relation to autism. Although numerous immune abnormalities have been identified in autism, inconsistent results have often been reported. To date, research in this area has largely involved small, uncontrolled studies. In order to bring clarity to this field, high-quality, systematic research is needed to explore the role of neuroimmunologic factors in autism. |
| En ligne : |
http://dx.doi.org/10.1016/j.rasd.2009.01.007 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=816 |
in Research in Autism Spectrum Disorders > 3-4 (October-December 2009) . - p.840-860
[article] Autism and immune factors: A comprehensive review [Texte imprimé et/ou numérique] / Kimberly A. STIGLER, Auteur ; Thayne L. SWEETEN, Auteur ; Christopher J. MCDOUGLE, Auteur ; David J. POSEY, Auteur . - 2009 . - p.840-860. Langues : Anglais ( eng) in Research in Autism Spectrum Disorders > 3-4 (October-December 2009) . - p.840-860
| Mots-clés : |
Autism Immune Infection Immunogenetics Cytokines Gastrointestinal Autoimmune |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Cases of autistic disorder (autism) have frequently been reported in association with congenital rubella and other infections. These observations stimulated further investigation into markers of immune function in autism. Postinfectious and autoimmune mechanisms of pathophysiology have been proposed. This review comprehensively addresses immune findings to date, including the role of viruses, neuroimmune factors, cellular and humoral immunity, immunogenetics, and immunotherapy in relation to autism. Although numerous immune abnormalities have been identified in autism, inconsistent results have often been reported. To date, research in this area has largely involved small, uncontrolled studies. In order to bring clarity to this field, high-quality, systematic research is needed to explore the role of neuroimmunologic factors in autism. |
| En ligne : |
http://dx.doi.org/10.1016/j.rasd.2009.01.007 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=816 |
|
Autism and immune factors: A comprehensive review in Research in Autism Spectrum Disorders, 3-4 (October-December 2009)
