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Autism and immune factors: A comprehensive review / Kimberly A. STIGLER in Research in Autism Spectrum Disorders, 3-4 (October-December 2009)
[article]
Titre : Autism and immune factors: A comprehensive review Type de document : Texte imprimé et/ou numérique Auteurs : Kimberly A. STIGLER, Auteur ; Thayne L. SWEETEN, Auteur ; Christopher J. MCDOUGLE, Auteur ; David J. POSEY, Auteur Année de publication : 2009 Article en page(s) : p.840-860 Langues : Anglais (eng) Mots-clés : Autism Immune Infection Immunogenetics Cytokines Gastrointestinal Autoimmune Index. décimale : PER Périodiques Résumé : Cases of autistic disorder (autism) have frequently been reported in association with congenital rubella and other infections. These observations stimulated further investigation into markers of immune function in autism. Postinfectious and autoimmune mechanisms of pathophysiology have been proposed. This review comprehensively addresses immune findings to date, including the role of viruses, neuroimmune factors, cellular and humoral immunity, immunogenetics, and immunotherapy in relation to autism. Although numerous immune abnormalities have been identified in autism, inconsistent results have often been reported. To date, research in this area has largely involved small, uncontrolled studies. In order to bring clarity to this field, high-quality, systematic research is needed to explore the role of neuroimmunologic factors in autism. En ligne : http://dx.doi.org/10.1016/j.rasd.2009.01.007 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=816
in Research in Autism Spectrum Disorders > 3-4 (October-December 2009) . - p.840-860[article] Autism and immune factors: A comprehensive review [Texte imprimé et/ou numérique] / Kimberly A. STIGLER, Auteur ; Thayne L. SWEETEN, Auteur ; Christopher J. MCDOUGLE, Auteur ; David J. POSEY, Auteur . - 2009 . - p.840-860.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 3-4 (October-December 2009) . - p.840-860
Mots-clés : Autism Immune Infection Immunogenetics Cytokines Gastrointestinal Autoimmune Index. décimale : PER Périodiques Résumé : Cases of autistic disorder (autism) have frequently been reported in association with congenital rubella and other infections. These observations stimulated further investigation into markers of immune function in autism. Postinfectious and autoimmune mechanisms of pathophysiology have been proposed. This review comprehensively addresses immune findings to date, including the role of viruses, neuroimmune factors, cellular and humoral immunity, immunogenetics, and immunotherapy in relation to autism. Although numerous immune abnormalities have been identified in autism, inconsistent results have often been reported. To date, research in this area has largely involved small, uncontrolled studies. In order to bring clarity to this field, high-quality, systematic research is needed to explore the role of neuroimmunologic factors in autism. En ligne : http://dx.doi.org/10.1016/j.rasd.2009.01.007 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=816