Dysbiosis in Gut Microbiota in Children Born Preterm Who Developed Autism Spectrum Disorder: A Pilot Study / Sadayuki FUJISHIRO in Journal of Autism and Developmental Disorders, 53-10 (October 2023)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 53-10 (October 2023) . - p.4012-4020 Titre : Dysbiosis in Gut Microbiota in Children Born Preterm Who Developed Autism Spectrum Disorder: A Pilot Study Type de document : Texte imprimé et/ou numérique Auteurs : Sadayuki FUJISHIRO, Auteur ; Shoji TSUJI, Auteur ; Shohei AKAGAWA, Auteur ; Yuko AKAGAWA, Auteur ; Sohsaku YAMANOUCHI, Auteur ; Yuko ISHIZAKI, Auteur ; Masaki HASHIYADA, Auteur ; Atsushi AKANE, Auteur ; Kazunari KANEKO, Auteur Article en page(s) : p.4012-4020 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The gut microbiota was reported to differ between children with autism spectrum disorder (ASD) and typically developing (TD) children, and dysbiosis of the gut microbiota in preterm infants is common. Here, we explored the characteristics of gut microbiota in children born preterm with ASD. We performed 16S rRNA gene sequencing using stool samples from ASD children born preterm and TD children born preterm. Alpha diversity was significantly greater in the ASD group. A comparison of beta diversity showed different clusters. Linear discriminant analysis effect size analysis revealed significantly more Firmicutes in the ASD group compared with the TD group. In conclusion, the gut microbiota in children born preterm differs between children with ASD and TD. En ligne : https://doi.org/10.1007/s10803-022-05682-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511 [article] Dysbiosis in Gut Microbiota in Children Born Preterm Who Developed Autism Spectrum Disorder: A Pilot Study [Texte imprimé et/ou numérique] / Sadayuki FUJISHIRO, Auteur ; Shoji TSUJI, Auteur ; Shohei AKAGAWA, Auteur ; Yuko AKAGAWA, Auteur ; Sohsaku YAMANOUCHI, Auteur ; Yuko ISHIZAKI, Auteur ; Masaki HASHIYADA, Auteur ; Atsushi AKANE, Auteur ; Kazunari KANEKO, Auteur . - p.4012-4020. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 53-10 (October 2023) . - p.4012-4020 Index. décimale : PER Périodiques Résumé : The gut microbiota was reported to differ between children with autism spectrum disorder (ASD) and typically developing (TD) children, and dysbiosis of the gut microbiota in preterm infants is common. Here, we explored the characteristics of gut microbiota in children born preterm with ASD. We performed 16S rRNA gene sequencing using stool samples from ASD children born preterm and TD children born preterm. Alpha diversity was significantly greater in the ASD group. A comparison of beta diversity showed different clusters. Linear discriminant analysis effect size analysis revealed significantly more Firmicutes in the ASD group compared with the TD group. In conclusion, the gut microbiota in children born preterm differs between children with ASD and TD. En ligne : https://doi.org/10.1007/s10803-022-05682-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511

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