[article]
Titre : |
Use of ECT in Autism Spectrum Disorder and/or Intellectual Disability: A Single Site Retrospective Analysis |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
Joshua R. SMITH, Auteur ; Corey E. HOPKINS, Auteur ; Jiangmei XIONG, Auteur ; James LUCCARELLI, Auteur ; Elizabeth SHULTZ, Auteur ; Simon VANDEKAR, Auteur |
Article en page(s) : |
p.963-982 |
Langues : |
Anglais (eng) |
Index. décimale : |
PER Périodiques |
Résumé : |
Autism spectrum disorder (ASD) and intellectual disability (ID) are heterogenous and prevalent conditions which may occur in isolation or as a co-morbidity. Psychiatric co-morbidity is common with limited treatment options. Preliminary research into electroconvulsive therapy (ECT) for these conditions has been encouraging. Thus, further research in this patient population is warranted. We conducted a 10-year retrospective review of the electronic medical record and identified intellectually capable individuals with ASD (IC-ASD), and those with ASD+ID or ID who received at least three ECT treatments. 32 patients were identified of which 30 (94%) experienced positive clinical response, defined as a clinical global impression-improvement (CGI-I) score of 3 or less. The average retrospective CGI-I score across all groups was 1.97, and results of a t-test performed on CGI-I scores indicated improvement across all groups [t = ? 16.54, df = 31, p<0.001, 95% CI = (1.72, 2.22)]. No significant adverse events were identified based on clinical documentation. Our findings further support previous ECT research in this patient population. |
En ligne : |
https://doi.org/10.1007/s10803-022-05868-6 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=524 |
in Journal of Autism and Developmental Disorders > 54-3 (March 2024) . - p.963-982
[article] Use of ECT in Autism Spectrum Disorder and/or Intellectual Disability: A Single Site Retrospective Analysis [Texte imprimé et/ou numérique] / Joshua R. SMITH, Auteur ; Corey E. HOPKINS, Auteur ; Jiangmei XIONG, Auteur ; James LUCCARELLI, Auteur ; Elizabeth SHULTZ, Auteur ; Simon VANDEKAR, Auteur . - p.963-982. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 54-3 (March 2024) . - p.963-982
Index. décimale : |
PER Périodiques |
Résumé : |
Autism spectrum disorder (ASD) and intellectual disability (ID) are heterogenous and prevalent conditions which may occur in isolation or as a co-morbidity. Psychiatric co-morbidity is common with limited treatment options. Preliminary research into electroconvulsive therapy (ECT) for these conditions has been encouraging. Thus, further research in this patient population is warranted. We conducted a 10-year retrospective review of the electronic medical record and identified intellectually capable individuals with ASD (IC-ASD), and those with ASD+ID or ID who received at least three ECT treatments. 32 patients were identified of which 30 (94%) experienced positive clinical response, defined as a clinical global impression-improvement (CGI-I) score of 3 or less. The average retrospective CGI-I score across all groups was 1.97, and results of a t-test performed on CGI-I scores indicated improvement across all groups [t = ? 16.54, df = 31, p<0.001, 95% CI = (1.72, 2.22)]. No significant adverse events were identified based on clinical documentation. Our findings further support previous ECT research in this patient population. |
En ligne : |
https://doi.org/10.1007/s10803-022-05868-6 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=524 |
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