Developmental abnormalities in infants and children with acquired immune deficiency syndrome (AIDS) and AIDS-related complex / Monica H. ULTMANN in Developmental Medicine & Child Neurology, 27-5 (October 1985)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > 27-5 (October 1985) . - p.563-571 Titre : Developmental abnormalities in infants and children with acquired immune deficiency syndrome (AIDS) and AIDS-related complex Type de document : Texte imprimé et/ou numérique Auteurs : Monica H. ULTMANN, Auteur ; Holly RUFF, Auteur ; Anita L. BELMAN, Auteur ; Brian E. NOVICK, Auteur ; Barbara CONE-WESSON, Auteur ; Herbert J. COHEN, Auteur ; Arye RUBINSTEIN, Auteur Année de publication : 1985 Article en page(s) : p.563-571 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Children with acquired immune deficiency syndrome (AIDS) display two types of clinical picture: a full-blown AIDS characterized by the presence of opportunistic infections and/or Kaposi's sarcoma and a prodromal stage now identified as AIDS-related complex (ARC). Neurological complications have been identified in infants and children with the disease. This paper discusses the developmental abnormalities in 16 pediatric patients, seven with AIDS and nine with ARC, ranging in age from six months to six years. In all cases, the mothers of these children either had ARC, AIDS and/or used intravenous drugs. Developmental histories showed delayed acquisition of milestones in most children following the diagnosis of AIDS or ARC, with delayed motor milestones consistently noted in both groups. Several children with AIDS actually lost milestones as their illness progressed; this has not occurred in the ARC group. Psychometric testing revealed more severe cognitive dysfunction in the group with AIDS. Involvement of the central nervous system was documented clinically, radiologically, and/or electrophysiologically in all patients with AIDS. In the ARC group the course of the illness has shown greater variability. Medical and social factors that may contribute to the developmental abnormalities are discussed. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=595 [article] Developmental abnormalities in infants and children with acquired immune deficiency syndrome (AIDS) and AIDS-related complex [Texte imprimé et/ou numérique] / Monica H. ULTMANN, Auteur ; Holly RUFF, Auteur ; Anita L. BELMAN, Auteur ; Brian E. NOVICK, Auteur ; Barbara CONE-WESSON, Auteur ; Herbert J. COHEN, Auteur ; Arye RUBINSTEIN, Auteur . - 1985 . - p.563-571. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > 27-5 (October 1985) . - p.563-571 Index. décimale : PER Périodiques Résumé : Children with acquired immune deficiency syndrome (AIDS) display two types of clinical picture: a full-blown AIDS characterized by the presence of opportunistic infections and/or Kaposi's sarcoma and a prodromal stage now identified as AIDS-related complex (ARC). Neurological complications have been identified in infants and children with the disease. This paper discusses the developmental abnormalities in 16 pediatric patients, seven with AIDS and nine with ARC, ranging in age from six months to six years. In all cases, the mothers of these children either had ARC, AIDS and/or used intravenous drugs. Developmental histories showed delayed acquisition of milestones in most children following the diagnosis of AIDS or ARC, with delayed motor milestones consistently noted in both groups. Several children with AIDS actually lost milestones as their illness progressed; this has not occurred in the ARC group. Psychometric testing revealed more severe cognitive dysfunction in the group with AIDS. Involvement of the central nervous system was documented clinically, radiologically, and/or electrophysiologically in all patients with AIDS. In the ARC group the course of the illness has shown greater variability. Medical and social factors that may contribute to the developmental abnormalities are discussed. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=595

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