Biobehavioral mechanisms underlying testosterone and mood relationships in peripubertal female adolescents / Elizabeth ANDERSEN in Development and Psychopathology, 36-4 (October 2024)  

Public ISBD [article]  inDevelopment and Psychopathology > 36-4 (October 2024) . - p.1638-1652 Titre : Biobehavioral mechanisms underlying testosterone and mood relationships in peripubertal female adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Elizabeth ANDERSEN, Auteur ; Julianna PRIM, Auteur ; Alana CAMPBELL, Auteur ; Crystal SCHILLER, Auteur ; Kayla BARESICH, Auteur ; Susan GIRDLER, Auteur Article en page(s) : p.1638-1652 Langues : Anglais (eng) Mots-clés : EEG  negative affect  peripuberty  stress  testosterone Index. décimale : PER Périodiques Résumé : The pubertal transition is characterized by pronounced sex hormone fluctuation, refinement of affective neural circuitry, and an increased risk of depression in female adolescents. Sex hormones, including testosterone, exert modulatory effects on frontal-limbic brain networks and are associated with emotion dysregulation and depressive symptoms. Weekly changes in hormones predict affective symptoms in peripubertal female adolescents, particularly in the context of stress; however, the biobehavioral mechanisms underlying hormone change and mood relationships during the pubertal transition have yet to be determined and was the objective of the present study. Forty-three peripubertal female adolescents (ages 11-14) collected 8-weekly salivary hormone (estrone, testosterone) samples and mood assessments to evaluate hormone-mood relationships, followed by a biobehavioral testing session with psychosocial stress and EEG. Within-person correlations between weekly hormone changes and corresponding mood were performed to determine individual differences in mood sensitivity to weekly hormone change. Increased frontal theta activity indexing emotion reactivity, reduced cortisol reactivity, and reduced vagal efficiency predicted the strength of the relationship between testosterone and mood. Further, testosterone-sensitivity strength was associated with the enhancement of negative affect following stress testing. Results identify divergent frontal theta and stress responses as potential biobehavioral mechanisms underlying mood sensitivity to peripubertal testosterone fluctuation. En ligne : https://dx.doi.org/10.1017/S0954579423000937 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=539 [article] Biobehavioral mechanisms underlying testosterone and mood relationships in peripubertal female adolescents [Texte imprimé et/ou numérique] / Elizabeth ANDERSEN, Auteur ; Julianna PRIM, Auteur ; Alana CAMPBELL, Auteur ; Crystal SCHILLER, Auteur ; Kayla BARESICH, Auteur ; Susan GIRDLER, Auteur . - p.1638-1652. Langues : Anglais (eng) in Development and Psychopathology > 36-4 (October 2024) . - p.1638-1652 Mots-clés : EEG  negative affect  peripuberty  stress  testosterone Index. décimale : PER Périodiques Résumé : The pubertal transition is characterized by pronounced sex hormone fluctuation, refinement of affective neural circuitry, and an increased risk of depression in female adolescents. Sex hormones, including testosterone, exert modulatory effects on frontal-limbic brain networks and are associated with emotion dysregulation and depressive symptoms. Weekly changes in hormones predict affective symptoms in peripubertal female adolescents, particularly in the context of stress; however, the biobehavioral mechanisms underlying hormone change and mood relationships during the pubertal transition have yet to be determined and was the objective of the present study. Forty-three peripubertal female adolescents (ages 11-14) collected 8-weekly salivary hormone (estrone, testosterone) samples and mood assessments to evaluate hormone-mood relationships, followed by a biobehavioral testing session with psychosocial stress and EEG. Within-person correlations between weekly hormone changes and corresponding mood were performed to determine individual differences in mood sensitivity to weekly hormone change. Increased frontal theta activity indexing emotion reactivity, reduced cortisol reactivity, and reduced vagal efficiency predicted the strength of the relationship between testosterone and mood. Further, testosterone-sensitivity strength was associated with the enhancement of negative affect following stress testing. Results identify divergent frontal theta and stress responses as potential biobehavioral mechanisms underlying mood sensitivity to peripubertal testosterone fluctuation. En ligne : https://dx.doi.org/10.1017/S0954579423000937 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=539

Life stress influences the relationship between sex hormone fluctuation and affective symptoms in peripubertal female adolescents / Hannah KLUSMANN ; Tory EISENLOHR-MOUL ; Kayla BARESICH ; Susan GIRDLER in Development and Psychopathology, 36-2 (May 2024)  

Public ISBD [article]  inDevelopment and Psychopathology > 36-2 (May 2024) . - p.821-833 Titre : Life stress influences the relationship between sex hormone fluctuation and affective symptoms in peripubertal female adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Hannah KLUSMANN, Auteur ; Tory EISENLOHR-MOUL, Auteur ; Kayla BARESICH, Auteur ; Susan GIRDLER, Auteur Article en page(s) : p.821-833 Langues : Anglais (eng) Mots-clés : depression  female  puberty  sex hormones  stress Index. décimale : PER Périodiques Résumé : Female adolescents have a greatly increased risk of depression starting at puberty, which continues throughout the reproductive lifespan. Sex hormone fluctuation has been highlighted as a key proximal precipitating factor in the development of mood disorders tied to reproductive events; however, hormone-induced affective state change is poorly understood in the pubertal transition. The present study investigated the impact of recent stressful life events on the relationship between sex hormone change and affective symptoms in peripubertal female participants. Thirty-five peripubertal participants (ages 11-14, premenarchal, or within 1 year of menarche) completed an assessment of stressful life events, and provided weekly salivary hormone collections [estrone, testosterone, dehydroepiandrosterone (DHEA)] and mood assessments for 8 weeks. Linear mixed models tested whether stressful life events provided a context in which within-person changes in hormones predicted weekly affective symptoms. Results indicated that exposure to stressful life events proximal to the pubertal transition influenced the directional effects of hormone change on affective symptoms. Specifically, greater affective symptoms were associated with increases in hormones in a high stress context and decreases in hormones in a low stress context. These findings provide support for stress-related hormone sensitivity as a diathesis for precipitating affective symptoms in the presence of pronounced peripubertal hormone flux. En ligne : https://dx.doi.org/10.1017/S095457942300010X Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=528 [article] Life stress influences the relationship between sex hormone fluctuation and affective symptoms in peripubertal female adolescents [Texte imprimé et/ou numérique] / Hannah KLUSMANN, Auteur ; Tory EISENLOHR-MOUL, Auteur ; Kayla BARESICH, Auteur ; Susan GIRDLER, Auteur . - p.821-833. Langues : Anglais (eng) in Development and Psychopathology > 36-2 (May 2024) . - p.821-833 Mots-clés : depression  female  puberty  sex hormones  stress Index. décimale : PER Périodiques Résumé : Female adolescents have a greatly increased risk of depression starting at puberty, which continues throughout the reproductive lifespan. Sex hormone fluctuation has been highlighted as a key proximal precipitating factor in the development of mood disorders tied to reproductive events; however, hormone-induced affective state change is poorly understood in the pubertal transition. The present study investigated the impact of recent stressful life events on the relationship between sex hormone change and affective symptoms in peripubertal female participants. Thirty-five peripubertal participants (ages 11-14, premenarchal, or within 1 year of menarche) completed an assessment of stressful life events, and provided weekly salivary hormone collections [estrone, testosterone, dehydroepiandrosterone (DHEA)] and mood assessments for 8 weeks. Linear mixed models tested whether stressful life events provided a context in which within-person changes in hormones predicted weekly affective symptoms. Results indicated that exposure to stressful life events proximal to the pubertal transition influenced the directional effects of hormone change on affective symptoms. Specifically, greater affective symptoms were associated with increases in hormones in a high stress context and decreases in hormones in a low stress context. These findings provide support for stress-related hormone sensitivity as a diathesis for precipitating affective symptoms in the presence of pronounced peripubertal hormone flux. En ligne : https://dx.doi.org/10.1017/S095457942300010X Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=528

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