Social Behavior and Autism Traits in a Sex Chromosomal Disorder: Klinefelter (47XXY) Syndrome / Sophie VAN RIJN in Journal of Autism and Developmental Disorders, 38-9 (October 2008)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 38-9 (October 2008) . - p.1573-3432 Titre : Social Behavior and Autism Traits in a Sex Chromosomal Disorder: Klinefelter (47XXY) Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Sophie VAN RIJN, Auteur ; Hanna SWAAB, Auteur ; André ALEMAN, Auteur ; René S. KAHN, Auteur Année de publication : 2008 Article en page(s) : p.1573-3432 Langues : Anglais (eng) Mots-clés : Klinefelter-syndrome Autism-traits X-chromosome Social-behavior XXY Index. décimale : PER Périodiques Résumé : Although Klinefelter syndrome (47,XXY) has been associated with psychosocial difficulties, knowledge of the social behavioral phenotype is limited. We examined specific social abilities and autism traits in Klinefelter syndrome. Scores of 31 XXY men on the Scale for Interpersonal Behavior and the Autism Spectrum Questionnaire were compared to 24 and 20 control men respectively. XXY men reported increased distress during social interactions and less engagement in specific social behaviors. In the XXY group, levels of autism traits were significantly higher across all dimensions of the autism phenotype. These findings call for a clinical investigation of vulnerability to autism in Klinefelter syndrome. Klinefelter syndrome might serve as a model for studying a role of the X chromosome in social behavioral dysfunction and autism-like behavior. En ligne : http://dx.doi.org/10.1007/s10803-008-0542-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=604 [article] Social Behavior and Autism Traits in a Sex Chromosomal Disorder: Klinefelter (47XXY) Syndrome [Texte imprimé et/ou numérique] / Sophie VAN RIJN, Auteur ; Hanna SWAAB, Auteur ; André ALEMAN, Auteur ; René S. KAHN, Auteur . - 2008 . - p.1573-3432. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 38-9 (October 2008) . - p.1573-3432 Mots-clés : Klinefelter-syndrome Autism-traits X-chromosome Social-behavior XXY Index. décimale : PER Périodiques Résumé : Although Klinefelter syndrome (47,XXY) has been associated with psychosocial difficulties, knowledge of the social behavioral phenotype is limited. We examined specific social abilities and autism traits in Klinefelter syndrome. Scores of 31 XXY men on the Scale for Interpersonal Behavior and the Autism Spectrum Questionnaire were compared to 24 and 20 control men respectively. XXY men reported increased distress during social interactions and less engagement in specific social behaviors. In the XXY group, levels of autism traits were significantly higher across all dimensions of the autism phenotype. These findings call for a clinical investigation of vulnerability to autism in Klinefelter syndrome. Klinefelter syndrome might serve as a model for studying a role of the X chromosome in social behavioral dysfunction and autism-like behavior. En ligne : http://dx.doi.org/10.1007/s10803-008-0542-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=604

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