Effects of fenfluramine on eight outpatients with the syndrome of autism / E. Gene STUBBS in Developmental Medicine & Child Neurology, 28-2 (April 1986)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > 28-2 (April 1986) . - p.229-235 Titre : Effects of fenfluramine on eight outpatients with the syndrome of autism Type de document : Texte imprimé et/ou numérique Auteurs : E. Gene STUBBS, Auteur ; Edward R. RITVO, Auteur ; Sarojini S. BUDDEN, Auteur ; Russell H. JACKSON, Auteur ; Leif G. TERDAL, Auteur Année de publication : 1986 Article en page(s) : p.229-235 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Fenfluramine was administered to eight autistic outpatients in a double-blind study to determine its effects on symptomatic behavior, developmental scores, blood serotonin levels and platelet counts. Two children benefited substantially according to academic and cognitive tests, parental and teacher reports and the principal investigator's clinical impressions. They also manifested behavioral and mood swings. The remaining six children showed varying degrees of response; one was withdrawn during the study by his parents. The greatest improvement occurred in children with an IQ above 40; the more severely retarded improved little, and primarily in the motor sphere. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=612 [article] Effects of fenfluramine on eight outpatients with the syndrome of autism [Texte imprimé et/ou numérique] / E. Gene STUBBS, Auteur ; Edward R. RITVO, Auteur ; Sarojini S. BUDDEN, Auteur ; Russell H. JACKSON, Auteur ; Leif G. TERDAL, Auteur . - 1986 . - p.229-235. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > 28-2 (April 1986) . - p.229-235 Index. décimale : PER Périodiques Résumé : Fenfluramine was administered to eight autistic outpatients in a double-blind study to determine its effects on symptomatic behavior, developmental scores, blood serotonin levels and platelet counts. Two children benefited substantially according to academic and cognitive tests, parental and teacher reports and the principal investigator's clinical impressions. They also manifested behavioral and mood swings. The remaining six children showed varying degrees of response; one was withdrawn during the study by his parents. The greatest improvement occurred in children with an IQ above 40; the more severely retarded improved little, and primarily in the motor sphere. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=612

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