Associations Between Brain Network Connectivity and Cognitive Measures in Autism Spectrum Disorder: A Post Hoc Analysis of a Parent Study “Evaluating the Safety and Efficacy of Transcranial Pulse Stimulation on Autism Spectrum Disorder” / Chun Liang HSU in Autism Research, 18-10 (October 2025)  

Public ISBD [article]  inAutism Research > 18-10 (October 2025) . - p.1965-1977 Titre : Associations Between Brain Network Connectivity and Cognitive Measures in Autism Spectrum Disorder: A Post Hoc Analysis of a Parent Study “Evaluating the Safety and Efficacy of Transcranial Pulse Stimulation on Autism Spectrum Disorder” Type de document : texte imprimé Auteurs : Chun Liang HSU, Auteur ; Eva MATT, Auteur ; Tommy Kwan Hin FONG, Auteur ; Joyce Yuen Ting LAM, Auteur ; Bolton CHAU, Auteur ; Calvin Pak Wing CHENG, Auteur ; Roland BEISTEINER, Auteur ; Teris CHEUNG, Auteur Article en page(s) : p.1965-1977 Langues : Anglais (eng) Mots-clés : adolescents  autism spectrum disorder  functional connectivity  neuromodulation  transcranial pulse stimulation Index. décimale : PER Périodiques Résumé : ABSTRACT This study presents a post hoc analysis of our parent study ?Evaluating the Safety and Efficacy of Transcranial Pulse Stimulation on Autism Spectrum Disorder? study which was a double-blind, sham-controlled, randomized controlled trial. In this study, we examined associations between changes in brain network connectivity and cognitive performance in young adolescents (12?17?years) with autism spectrum disorder (ASD) following the administration of transcranial pulse stimulation (TPS) which is considered non-invasive, evidenced-based brain stimulation for neurodegenerative disorders and neuropsychiatric disorders. Our findings indicate that increased connectivity in specific brain networks is associated with improvements in cognitive measures, suggesting that connectivity changes may underpin cognitive changes observed after six TPS intervention. These results highlight potential neural mechanisms underlying cognitive improvements in ASD, although causality cannot be inferred from these associations. Trial Registration: ClinicalTrials.gov identifier: NCT05408793 En ligne : https://doi.org/10.1002/aur.70093 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=569 [article] Associations Between Brain Network Connectivity and Cognitive Measures in Autism Spectrum Disorder: A Post Hoc Analysis of a Parent Study “Evaluating the Safety and Efficacy of Transcranial Pulse Stimulation on Autism Spectrum Disorder” [texte imprimé] / Chun Liang HSU, Auteur ; Eva MATT, Auteur ; Tommy Kwan Hin FONG, Auteur ; Joyce Yuen Ting LAM, Auteur ; Bolton CHAU, Auteur ; Calvin Pak Wing CHENG, Auteur ; Roland BEISTEINER, Auteur ; Teris CHEUNG, Auteur . - p.1965-1977. Langues : Anglais (eng) in Autism Research > 18-10 (October 2025) . - p.1965-1977 Mots-clés : adolescents  autism spectrum disorder  functional connectivity  neuromodulation  transcranial pulse stimulation Index. décimale : PER Périodiques Résumé : ABSTRACT This study presents a post hoc analysis of our parent study ?Evaluating the Safety and Efficacy of Transcranial Pulse Stimulation on Autism Spectrum Disorder? study which was a double-blind, sham-controlled, randomized controlled trial. In this study, we examined associations between changes in brain network connectivity and cognitive performance in young adolescents (12?17?years) with autism spectrum disorder (ASD) following the administration of transcranial pulse stimulation (TPS) which is considered non-invasive, evidenced-based brain stimulation for neurodegenerative disorders and neuropsychiatric disorders. Our findings indicate that increased connectivity in specific brain networks is associated with improvements in cognitive measures, suggesting that connectivity changes may underpin cognitive changes observed after six TPS intervention. These results highlight potential neural mechanisms underlying cognitive improvements in ASD, although causality cannot be inferred from these associations. Trial Registration: ClinicalTrials.gov identifier: NCT05408793 En ligne : https://doi.org/10.1002/aur.70093 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=569

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