Caregiver-Mediated Early Support Program Delivered Online Versus Care-as-Usual for Infants at Elevated Familial Likelihood for Autism: A Parallel, Assessor Masked, Feasibility Randomized Controlled Trial in India / Shoba S. MEERA in Autism Research, 18-11 (November 2025)  

Public ISBD [article]  inAutism Research > 18-11 (November 2025) . - p.2345-2355 Titre : Caregiver-Mediated Early Support Program Delivered Online Versus Care-as-Usual for Infants at Elevated Familial Likelihood for Autism: A Parallel, Assessor Masked, Feasibility Randomized Controlled Trial in India Type de document : texte imprimé Auteurs : Shoba S. MEERA, Auteur ; Prathyusha VASUKI, Auteur ; Malavi SRIKAR, Auteur ; Reny RAJU, Auteur ; Divya SWAMINATHAN, Auteur ; Shree VOLME, Auteur ; Rachel Elizabeth JOHNSON, Auteur ; Linda R. WATSON, Auteur ; Andrew WHITEHOUSE, Auteur ; Mirko ULJAREVIĆ, Auteur ; Ming Wai WAN, Auteur ; John Vijay SAGAR, Auteur ; Deepa Bhat NAIR, Auteur Article en page(s) : p.2345-2355 Langues : Anglais (eng) Mots-clés : autism  caregiver responsiveness  early intervention  India  infant siblings  LiL' STEPS  online intervention Index. décimale : PER Périodiques Résumé : ABSTRACT LiL' STEPS (Language development n?=?12) using fixed block randomization. While families in the former group received the LiL' STEPS early support program, those in the latter did not avail themselves of any early supports. Assessors were masked to group status. The primary outcome was caregiver sensitive responsiveness, assessed using the Manchester Assessment for Caregiver-Infant Interaction (MACI). Secondary outcomes included caregiver-reported measures of social communication and language. Outcomes were measured at three time points: baseline (T1), 12?weeks post-baseline (T2), and 12?weeks after program completion (T3). Intention-to-treat analyses were performed using linear mixed models. No significant treatment effects were found between baseline (T1) and endpoint (T3) on the primary or secondary outcomes. However, significant, large, positive treatment effects were observed for caregiver sensitive responsiveness (??=?1.48; 95% CI?=?0.51?2.34; d?=?1.15) and dyadic mutuality (??=?1.22; 95% CI?=?0.03?2.15; d?=?1.01) between baseline (T1) and T2, highlighting the need for ongoing support between T2 and T3?a key direction for future large scale efficacy trials. En ligne : https://doi.org/10.1002/aur.70116 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571 [article] Caregiver-Mediated Early Support Program Delivered Online Versus Care-as-Usual for Infants at Elevated Familial Likelihood for Autism: A Parallel, Assessor Masked, Feasibility Randomized Controlled Trial in India [texte imprimé] / Shoba S. MEERA, Auteur ; Prathyusha VASUKI, Auteur ; Malavi SRIKAR, Auteur ; Reny RAJU, Auteur ; Divya SWAMINATHAN, Auteur ; Shree VOLME, Auteur ; Rachel Elizabeth JOHNSON, Auteur ; Linda R. WATSON, Auteur ; Andrew WHITEHOUSE, Auteur ; Mirko ULJAREVIĆ, Auteur ; Ming Wai WAN, Auteur ; John Vijay SAGAR, Auteur ; Deepa Bhat NAIR, Auteur . - p.2345-2355. Langues : Anglais (eng) in Autism Research > 18-11 (November 2025) . - p.2345-2355 Mots-clés : autism  caregiver responsiveness  early intervention  India  infant siblings  LiL' STEPS  online intervention Index. décimale : PER Périodiques Résumé : ABSTRACT LiL' STEPS (Language development n?=?12) using fixed block randomization. While families in the former group received the LiL' STEPS early support program, those in the latter did not avail themselves of any early supports. Assessors were masked to group status. The primary outcome was caregiver sensitive responsiveness, assessed using the Manchester Assessment for Caregiver-Infant Interaction (MACI). Secondary outcomes included caregiver-reported measures of social communication and language. Outcomes were measured at three time points: baseline (T1), 12?weeks post-baseline (T2), and 12?weeks after program completion (T3). Intention-to-treat analyses were performed using linear mixed models. No significant treatment effects were found between baseline (T1) and endpoint (T3) on the primary or secondary outcomes. However, significant, large, positive treatment effects were observed for caregiver sensitive responsiveness (??=?1.48; 95% CI?=?0.51?2.34; d?=?1.15) and dyadic mutuality (??=?1.22; 95% CI?=?0.03?2.15; d?=?1.01) between baseline (T1) and T2, highlighting the need for ongoing support between T2 and T3?a key direction for future large scale efficacy trials. En ligne : https://doi.org/10.1002/aur.70116 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571

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