[article]
| Titre : |
Current research and interventions for dietary patterns in children with Autism Spectrum Disorder: A systematic review |
| Type de document : |
texte imprimé |
| Auteurs : |
Ting LI, Auteur ; Chen ZHONG, Auteur |
| Article en page(s) : |
p.202903 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Autism Spectrum Disorder Dietary patterns Food selectivity Nutritional interventions Microbiota-gut-brain axis |
| Index. décimale : |
PER Périodiques |
| Résumé : |
This review systematically evaluated the research progress on the dietary behavior characteristics and intervention strategies for children with Autism Spectrum Disorder (ASD). A substantial body of evidence indicated that children with ASD frequently exhibit significant dietary behavior challenges, including food selectivity, picky eating, and food refusal, which may increase the risk of nutritional imbalances and related comorbidities. Recent studies have elucidated the complex interactions between these atypical eating behaviors and neurodevelopmental abnormalities, gut microbiota dysbiosis, immune dysfunction, and metabolic disturbances. The microbiota-gut-brain axis (MGBA) was considered a central mediating mechanism in this context. Current intervention strategies primarily encompassed specialized dietary therapies, targeted nutritional supplementation, behavioral interventions, and microbiota-directed therapies. Promising recent randomized controlled trials have begun to address this gap, showing for example the specific benefits of Limosilactobacillus reuteri adjunctive therapy for social functioning and the potential of mitochondrial-targeted agents to produce clinically meaningful improvements in core symptoms in selected subgroups. However, evidence regarding the efficacy and generalizability of these interventions remained inconsistent. This article synthesized the latest evidence-based findings to assess the applications and limitations of existing intervention strategies, and highlights future research directions. Further studies should focus on elucidating the precise mechanisms of the MGBA, developing individualized nutrition intervention plans, and conducting long-term rigorous evaluations of their efficacy, thereby providing a more reliable theoretical foundation and practical guidance for the clinical nutritional management and comprehensive care of children with ASD. |
| En ligne : |
https://doi.org/10.1016/j.reia.2026.202903 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=585 |
in Research in Autism > 133 (May 2026) . - p.202903
[article] Current research and interventions for dietary patterns in children with Autism Spectrum Disorder: A systematic review [texte imprimé] / Ting LI, Auteur ; Chen ZHONG, Auteur . - p.202903. Langues : Anglais ( eng) in Research in Autism > 133 (May 2026) . - p.202903
| Mots-clés : |
Autism Spectrum Disorder Dietary patterns Food selectivity Nutritional interventions Microbiota-gut-brain axis |
| Index. décimale : |
PER Périodiques |
| Résumé : |
This review systematically evaluated the research progress on the dietary behavior characteristics and intervention strategies for children with Autism Spectrum Disorder (ASD). A substantial body of evidence indicated that children with ASD frequently exhibit significant dietary behavior challenges, including food selectivity, picky eating, and food refusal, which may increase the risk of nutritional imbalances and related comorbidities. Recent studies have elucidated the complex interactions between these atypical eating behaviors and neurodevelopmental abnormalities, gut microbiota dysbiosis, immune dysfunction, and metabolic disturbances. The microbiota-gut-brain axis (MGBA) was considered a central mediating mechanism in this context. Current intervention strategies primarily encompassed specialized dietary therapies, targeted nutritional supplementation, behavioral interventions, and microbiota-directed therapies. Promising recent randomized controlled trials have begun to address this gap, showing for example the specific benefits of Limosilactobacillus reuteri adjunctive therapy for social functioning and the potential of mitochondrial-targeted agents to produce clinically meaningful improvements in core symptoms in selected subgroups. However, evidence regarding the efficacy and generalizability of these interventions remained inconsistent. This article synthesized the latest evidence-based findings to assess the applications and limitations of existing intervention strategies, and highlights future research directions. Further studies should focus on elucidating the precise mechanisms of the MGBA, developing individualized nutrition intervention plans, and conducting long-term rigorous evaluations of their efficacy, thereby providing a more reliable theoretical foundation and practical guidance for the clinical nutritional management and comprehensive care of children with ASD. |
| En ligne : |
https://doi.org/10.1016/j.reia.2026.202903 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=585 |
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