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Auteur Joseph SERGEANT |
Documents disponibles écrits par cet auteur (1)
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Neurocognitive predictors of substance use disorders and nicotine dependence in ADHD probands, their unaffected siblings, and controls: a 4-year prospective follow-up / Annabeth P. GROENMAN in Journal of Child Psychology and Psychiatry, 56-5 (May 2015)
[article]
Titre : Neurocognitive predictors of substance use disorders and nicotine dependence in ADHD probands, their unaffected siblings, and controls: a 4-year prospective follow-up Type de document : Texte imprimé et/ou numérique Auteurs : Annabeth P. GROENMAN, Auteur ; Jaap OOSTERLAAN, Auteur ; Corina U. GREVEN, Auteur ; Pieter Jelle VUIJK, Auteur ; Nanda N. ROMMELSE, Auteur ; Barbara FRANKE, Auteur ; Catharina A. HARTMAN, Auteur ; Pieter J. HOEKSTRA, Auteur ; Joseph SERGEANT, Auteur ; Stephen V. FARAONE, Auteur ; Jan K. BUITELAAR, Auteur Article en page(s) : p.521-529 Langues : Anglais (eng) Mots-clés : Attention-deficit/Hyperactivity disorder substance use disorder nicotine dependence neurocognitive functions Index. décimale : PER Périodiques Résumé : Background Attention-Deficit/Hyperactivity Disorder (ADHD) is a risk factor for substance use disorders (SUDs) and nicotine dependence (ND). Neurocognitive deficits may predict the increased risk of developing SUDs and nicotine dependence. Methods This study comprised three groups derived from the Dutch part of the International Multicenter ADHD Genetics (IMAGE) study: ADHD probands (n = 294), unaffected siblings (n = 161), and controls (n = 214). At baseline (age = 12.2), a range of neurocognitive functions was assessed including executive functions (inhibition, working memory, timing), measures of motor functioning (motor timing and tracking) and IQ. After a mean follow-up of 4.2 years, SUDs and ND were assessed. Results None of the neurocognitive functions predicted later SUDs or ND in ADHD probands, even after controlling for medication use and conduct disorder. Slower response inhibition predicted later nicotine dependence in unaffected siblings (OR = 2.06, 95% CI = 1.22–3.48), and lower IQ predicted increased risk for SUDs in controls (OR = 1.96, 95% CI = 1.12–3.44). Conclusions Cold executive functions, motor functioning, and IQ did not predict the elevated risk of SUDs and ND in ADHD. Future studies should target ‘hot’ executive functions such as reward processing as risk factors for SUDs or ND. En ligne : http://dx.doi.org/10.1111/jcpp.12315 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260
in Journal of Child Psychology and Psychiatry > 56-5 (May 2015) . - p.521-529[article] Neurocognitive predictors of substance use disorders and nicotine dependence in ADHD probands, their unaffected siblings, and controls: a 4-year prospective follow-up [Texte imprimé et/ou numérique] / Annabeth P. GROENMAN, Auteur ; Jaap OOSTERLAAN, Auteur ; Corina U. GREVEN, Auteur ; Pieter Jelle VUIJK, Auteur ; Nanda N. ROMMELSE, Auteur ; Barbara FRANKE, Auteur ; Catharina A. HARTMAN, Auteur ; Pieter J. HOEKSTRA, Auteur ; Joseph SERGEANT, Auteur ; Stephen V. FARAONE, Auteur ; Jan K. BUITELAAR, Auteur . - p.521-529.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 56-5 (May 2015) . - p.521-529
Mots-clés : Attention-deficit/Hyperactivity disorder substance use disorder nicotine dependence neurocognitive functions Index. décimale : PER Périodiques Résumé : Background Attention-Deficit/Hyperactivity Disorder (ADHD) is a risk factor for substance use disorders (SUDs) and nicotine dependence (ND). Neurocognitive deficits may predict the increased risk of developing SUDs and nicotine dependence. Methods This study comprised three groups derived from the Dutch part of the International Multicenter ADHD Genetics (IMAGE) study: ADHD probands (n = 294), unaffected siblings (n = 161), and controls (n = 214). At baseline (age = 12.2), a range of neurocognitive functions was assessed including executive functions (inhibition, working memory, timing), measures of motor functioning (motor timing and tracking) and IQ. After a mean follow-up of 4.2 years, SUDs and ND were assessed. Results None of the neurocognitive functions predicted later SUDs or ND in ADHD probands, even after controlling for medication use and conduct disorder. Slower response inhibition predicted later nicotine dependence in unaffected siblings (OR = 2.06, 95% CI = 1.22–3.48), and lower IQ predicted increased risk for SUDs in controls (OR = 1.96, 95% CI = 1.12–3.44). Conclusions Cold executive functions, motor functioning, and IQ did not predict the elevated risk of SUDs and ND in ADHD. Future studies should target ‘hot’ executive functions such as reward processing as risk factors for SUDs or ND. En ligne : http://dx.doi.org/10.1111/jcpp.12315 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260