Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Détail de l'auteur
Auteur Leonhard QUINTERO |
Documents disponibles écrits par cet auteur (1)
Faire une suggestion Affiner la recherche
Reduced hair cortisol after maltreatment mediates externalizing symptoms in middle childhood and adolescence / Lars O. WHITE in Journal of Child Psychology and Psychiatry, 58-9 (September 2017)
[article]
Titre : Reduced hair cortisol after maltreatment mediates externalizing symptoms in middle childhood and adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Lars O. WHITE, Auteur ; Marcus ISING, Auteur ; Kai VON KLITZING, Auteur ; Susan SIERAU, Auteur ; Andrea MICHEL, Auteur ; Annette M. KLEIN, Auteur ; Anna ANDREAS, Auteur ; Jan KEIL, Auteur ; Leonhard QUINTERO, Auteur ; Bertram MÜLLER-MYHSOK, Auteur ; Manfred UHR, Auteur ; Ruth GAUSCHE, Auteur ; Jody T. MANLY, Auteur ; Michael J. CROWLEY, Auteur ; Clemens KIRSCHBAUM, Auteur ; Tobias STALDER, Auteur Article en page(s) : p.998-1007 Langues : Anglais (eng) Mots-clés : Hair cortisol maltreatment neglect externalizing symptoms Index. décimale : PER Périodiques Résumé : Background The enduring impact of childhood maltreatment on biological systems and ensuing psychopathology remains incompletely understood. Long-term effects of stress may be reflected in cumulative cortisol secretion over several months, which is now quantifiable via hair cortisol concentrations (HCC). We conducted a first comprehensive investigation utilizing the potential of hair cortisol analysis in a large sample of maltreated and nonmaltreated children and adolescents. Method Participants included 537 children and adolescents (3–16 years; 272 females) with maltreatment (n = 245) or without maltreatment histories (n = 292). Maltreated subjects were recruited from child protection services (CPS; n = 95), youth psychiatric services (n = 56), and the community (n = 94). Maltreatment was coded using the Maltreatment Classification System drawing on caregiver interviews and complemented with CPS records. Caregivers and teachers reported on child mental health. HCC were assessed in the first 3 cm hair segment. Results Analyses uniformly supported that maltreatment coincides with a gradual and dose-dependent reduction in HCC from 9 to 10 years onwards relative to nonmaltreated controls. This pattern emerged consistently from both group comparisons between maltreated and nonmaltreated subjects (27.6% HCC reduction in maltreated 9–16-year-olds) and dimensional analyses within maltreated subjects, with lower HCC related to greater maltreatment chronicity and number of subtypes. Moreover, both group comparisons and dimensional analyses within maltreated youth revealed that relative HCC reduction mediates the effect of maltreatment on externalizing symptoms. Conclusions From middle childhood onwards, maltreatment coincides with a relative reduction in cortisol secretion, which, in turn, may predispose to externalizing symptoms. En ligne : http://dx.doi.org/10.1111/jcpp.12700 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=317
in Journal of Child Psychology and Psychiatry > 58-9 (September 2017) . - p.998-1007[article] Reduced hair cortisol after maltreatment mediates externalizing symptoms in middle childhood and adolescence [Texte imprimé et/ou numérique] / Lars O. WHITE, Auteur ; Marcus ISING, Auteur ; Kai VON KLITZING, Auteur ; Susan SIERAU, Auteur ; Andrea MICHEL, Auteur ; Annette M. KLEIN, Auteur ; Anna ANDREAS, Auteur ; Jan KEIL, Auteur ; Leonhard QUINTERO, Auteur ; Bertram MÜLLER-MYHSOK, Auteur ; Manfred UHR, Auteur ; Ruth GAUSCHE, Auteur ; Jody T. MANLY, Auteur ; Michael J. CROWLEY, Auteur ; Clemens KIRSCHBAUM, Auteur ; Tobias STALDER, Auteur . - p.998-1007.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 58-9 (September 2017) . - p.998-1007
Mots-clés : Hair cortisol maltreatment neglect externalizing symptoms Index. décimale : PER Périodiques Résumé : Background The enduring impact of childhood maltreatment on biological systems and ensuing psychopathology remains incompletely understood. Long-term effects of stress may be reflected in cumulative cortisol secretion over several months, which is now quantifiable via hair cortisol concentrations (HCC). We conducted a first comprehensive investigation utilizing the potential of hair cortisol analysis in a large sample of maltreated and nonmaltreated children and adolescents. Method Participants included 537 children and adolescents (3–16 years; 272 females) with maltreatment (n = 245) or without maltreatment histories (n = 292). Maltreated subjects were recruited from child protection services (CPS; n = 95), youth psychiatric services (n = 56), and the community (n = 94). Maltreatment was coded using the Maltreatment Classification System drawing on caregiver interviews and complemented with CPS records. Caregivers and teachers reported on child mental health. HCC were assessed in the first 3 cm hair segment. Results Analyses uniformly supported that maltreatment coincides with a gradual and dose-dependent reduction in HCC from 9 to 10 years onwards relative to nonmaltreated controls. This pattern emerged consistently from both group comparisons between maltreated and nonmaltreated subjects (27.6% HCC reduction in maltreated 9–16-year-olds) and dimensional analyses within maltreated subjects, with lower HCC related to greater maltreatment chronicity and number of subtypes. Moreover, both group comparisons and dimensional analyses within maltreated youth revealed that relative HCC reduction mediates the effect of maltreatment on externalizing symptoms. Conclusions From middle childhood onwards, maltreatment coincides with a relative reduction in cortisol secretion, which, in turn, may predispose to externalizing symptoms. En ligne : http://dx.doi.org/10.1111/jcpp.12700 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=317