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Détail de l'auteur
Auteur G. WAN |
Documents disponibles écrits par cet auteur (2)
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Applying Eye Tracking to Identify Autism Spectrum Disorder in Children / G. WAN in Journal of Autism and Developmental Disorders, 49-1 (January 2019)
[article]
Titre : Applying Eye Tracking to Identify Autism Spectrum Disorder in Children Type de document : Texte imprimé et/ou numérique Auteurs : G. WAN, Auteur ; X. KONG, Auteur ; B. SUN, Auteur ; S. YU, Auteur ; Y. TU, Auteur ; J. PARK, Auteur ; C. LANG, Auteur ; M. KOH, Auteur ; Z. WEI, Auteur ; Z. FENG, Auteur ; Y. LIN, Auteur ; J. KONG, Auteur Article en page(s) : p.209-215 Langues : Anglais (eng) Mots-clés : Autism Eye tracking Face Fixation time Machine learning Index. décimale : PER Périodiques Résumé : Eye tracking (ET) holds potential for the early detection of autism spectrum disorder (ASD). To overcome the difficulties of working with young children, developing a short and informative paradigm is crucial for ET. We investigated the fixation times of 37 ASD and 37 typically developing (TD) children ages 4-6 watching a 10-second video of a female speaking. ASD children showed significant reductions in fixation time at six areas of interest. Furthermore, discriminant analysis revealed fixation times at the mouth and body could significantly discriminate ASD from TD with a classification accuracy of 85.1%, sensitivity of 86.5%, and specificity of 83.8%. Our study suggests that a short video clip may provide enough information to distinguish ASD from TD children. En ligne : http://dx.doi.org/10.1007/s10803-018-3690-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=377
in Journal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.209-215[article] Applying Eye Tracking to Identify Autism Spectrum Disorder in Children [Texte imprimé et/ou numérique] / G. WAN, Auteur ; X. KONG, Auteur ; B. SUN, Auteur ; S. YU, Auteur ; Y. TU, Auteur ; J. PARK, Auteur ; C. LANG, Auteur ; M. KOH, Auteur ; Z. WEI, Auteur ; Z. FENG, Auteur ; Y. LIN, Auteur ; J. KONG, Auteur . - p.209-215.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.209-215
Mots-clés : Autism Eye tracking Face Fixation time Machine learning Index. décimale : PER Périodiques Résumé : Eye tracking (ET) holds potential for the early detection of autism spectrum disorder (ASD). To overcome the difficulties of working with young children, developing a short and informative paradigm is crucial for ET. We investigated the fixation times of 37 ASD and 37 typically developing (TD) children ages 4-6 watching a 10-second video of a female speaking. ASD children showed significant reductions in fixation time at six areas of interest. Furthermore, discriminant analysis revealed fixation times at the mouth and body could significantly discriminate ASD from TD with a classification accuracy of 85.1%, sensitivity of 86.5%, and specificity of 83.8%. Our study suggests that a short video clip may provide enough information to distinguish ASD from TD children. En ligne : http://dx.doi.org/10.1007/s10803-018-3690-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=377 Atypical longitudinal development of speech-evoked auditory brainstem response in preschool children with autism spectrum disorders / J. CHEN in Autism Research, 12-7 (July 2019)
[article]
Titre : Atypical longitudinal development of speech-evoked auditory brainstem response in preschool children with autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : J. CHEN, Auteur ; C. LIANG, Auteur ; Z. WEI, Auteur ; Z. CUI, Auteur ; X. KONG, Auteur ; C. J. DONG, Auteur ; Y. LAI, Auteur ; Z. PENG, Auteur ; G. WAN, Auteur Année de publication : 2019 Article en page(s) : p.1022-1031 Langues : Anglais (eng) Mots-clés : autism spectrum disorders language impairment preschool child speech-evoked auditory brainstem response Index. décimale : PER Périodiques Résumé : Language impairment is common in children with autism spectrum disorders (ASDs). Previous research has shown that this disability may be, in part, due to atypical auditory processing of speech stimuli. However, how speech sounds are processed in children with ASD remains largely unknown. The present study assessed the developmental pattern of auditory information processing at the level of the brainstem in preschool children with ASD using speech-evoked auditory brainstem response (speech-ABR). Children with ASD (N = 15) and of typical developing (TD) (N = 20), both of preschool age, were enrolled. The speech-ABRs recorded at two different time points (T1 and T2; 9.68 months apart on average) were virtually identical in the TD group. However, in the ASD group, the wave V latency of speech-ABR was significantly shortened and the amplitudes of wave A and C were significantly larger at T2, compared to those recorded at T1 (10.78 months apart on average). Compared to the TD group, the wave V and A latencies were prolonged at T1, whereas the wave E amplitude decreased and wave F latency prolonged at T2. There was a positive partial correlation between the language performance and the wave A amplitude in the ASD group. These results indicate that auditory processing at the subcortical level is well-developed in the TD preschool children, but is immature and abnormal in the children with ASD at the same ages. Thus, aberrant speech processing at the brainstem level may contribute significantly to the language impairment in children with ASD at preschool ages. Autism Res 2019, 12: 1022-1031. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Language impairment is common in children with autism spectrum disorders (ASDs). We investigated the developmental pattern of subcortical auditory processing by monitoring changes in the speech-evoked auditory brainstem response (speech-ABR) over a period of 10 months in preschool children. Our results show that subcortical auditory processing is impaired and immature in children with ASD compared with age-matched, typically developing children. The results suggest that speech-ABR may be used as an objective measure in evaluating the language performance of children with ASD. The results also suggest that aberrant speech processing at the level of the brainstem may contribute significantly to the language impairment in preschool children with ASD. En ligne : http://dx.doi.org/10.1002/aur.2110 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402
in Autism Research > 12-7 (July 2019) . - p.1022-1031[article] Atypical longitudinal development of speech-evoked auditory brainstem response in preschool children with autism spectrum disorders [Texte imprimé et/ou numérique] / J. CHEN, Auteur ; C. LIANG, Auteur ; Z. WEI, Auteur ; Z. CUI, Auteur ; X. KONG, Auteur ; C. J. DONG, Auteur ; Y. LAI, Auteur ; Z. PENG, Auteur ; G. WAN, Auteur . - 2019 . - p.1022-1031.
Langues : Anglais (eng)
in Autism Research > 12-7 (July 2019) . - p.1022-1031
Mots-clés : autism spectrum disorders language impairment preschool child speech-evoked auditory brainstem response Index. décimale : PER Périodiques Résumé : Language impairment is common in children with autism spectrum disorders (ASDs). Previous research has shown that this disability may be, in part, due to atypical auditory processing of speech stimuli. However, how speech sounds are processed in children with ASD remains largely unknown. The present study assessed the developmental pattern of auditory information processing at the level of the brainstem in preschool children with ASD using speech-evoked auditory brainstem response (speech-ABR). Children with ASD (N = 15) and of typical developing (TD) (N = 20), both of preschool age, were enrolled. The speech-ABRs recorded at two different time points (T1 and T2; 9.68 months apart on average) were virtually identical in the TD group. However, in the ASD group, the wave V latency of speech-ABR was significantly shortened and the amplitudes of wave A and C were significantly larger at T2, compared to those recorded at T1 (10.78 months apart on average). Compared to the TD group, the wave V and A latencies were prolonged at T1, whereas the wave E amplitude decreased and wave F latency prolonged at T2. There was a positive partial correlation between the language performance and the wave A amplitude in the ASD group. These results indicate that auditory processing at the subcortical level is well-developed in the TD preschool children, but is immature and abnormal in the children with ASD at the same ages. Thus, aberrant speech processing at the brainstem level may contribute significantly to the language impairment in children with ASD at preschool ages. Autism Res 2019, 12: 1022-1031. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Language impairment is common in children with autism spectrum disorders (ASDs). We investigated the developmental pattern of subcortical auditory processing by monitoring changes in the speech-evoked auditory brainstem response (speech-ABR) over a period of 10 months in preschool children. Our results show that subcortical auditory processing is impaired and immature in children with ASD compared with age-matched, typically developing children. The results suggest that speech-ABR may be used as an objective measure in evaluating the language performance of children with ASD. The results also suggest that aberrant speech processing at the level of the brainstem may contribute significantly to the language impairment in preschool children with ASD. En ligne : http://dx.doi.org/10.1002/aur.2110 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402