Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Détail de l'auteur
Auteur Sofia URIBE |
Documents disponibles écrits par cet auteur (1)
Faire une suggestion Affiner la recherche
Auditory evoked potentials in adolescents with autism: An investigation of brain development, intellectual impairment, and neural encoding / Sophie SCHWARTZ in Autism Research, 16-10 (October 2023)
[article]
Titre : Auditory evoked potentials in adolescents with autism: An investigation of brain development, intellectual impairment, and neural encoding Type de document : Texte imprimé et/ou numérique Auteurs : Sophie SCHWARTZ, Auteur ; Le WANG, Auteur ; Sofia URIBE, Auteur ; Barbara G. SHINN-CUNNINGHAM, Auteur ; Helen TAGER-FLUSBERG, Auteur Article en page(s) : p.1859-1876 Index. décimale : PER Périodiques Résumé : Abstract Limited research has evaluated neural encoding of sounds from a developmental perspective in individuals with autism (ASD), especially among those with intellectual disability. We compared auditory evoked potentials (AEPs) in autistic adolescents with a wide range of intellectual abilities (n?=?40, NVIQ 30-160) to both age-matched cognitively able neurotypical adolescent controls (NT-A, n?=?37) and younger neurotypical children (NT-C, n?=?27) to assess potential developmental delays. In addition to a classic measure of peak amplitude, we calculated a continuous measure of intra-class correlation (ICC) between each adolescent participant's AEP and the age-normative, average AEP waveforms calculated from NT-C and NT-A to study differences in signal morphology. We found that peak amplitudes of neural responses were significantly smaller in autistic adolescents compared to NT-A. We also found that the AEP morphology of autistic adolescents looked more like NT-A peers than NT-C but was still significantly different from NT-A AEP waveforms. Results suggest that AEPs of autistic adolescents present differently from NTs, regardless of age, and differences cannot be accounted for by developmental delay. Nonverbal intelligence significantly predicted how closely each adolescent's AEP resembled the age-normed waveform. These results support an evolving theory that the degree of disruption in early neural responses to low-level inputs is reflected in the severity of intellectual impairments in autism. En ligne : https://doi.org/10.1002/aur.3003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=513
in Autism Research > 16-10 (October 2023) . - p.1859-1876[article] Auditory evoked potentials in adolescents with autism: An investigation of brain development, intellectual impairment, and neural encoding [Texte imprimé et/ou numérique] / Sophie SCHWARTZ, Auteur ; Le WANG, Auteur ; Sofia URIBE, Auteur ; Barbara G. SHINN-CUNNINGHAM, Auteur ; Helen TAGER-FLUSBERG, Auteur . - p.1859-1876.
in Autism Research > 16-10 (October 2023) . - p.1859-1876
Index. décimale : PER Périodiques Résumé : Abstract Limited research has evaluated neural encoding of sounds from a developmental perspective in individuals with autism (ASD), especially among those with intellectual disability. We compared auditory evoked potentials (AEPs) in autistic adolescents with a wide range of intellectual abilities (n?=?40, NVIQ 30-160) to both age-matched cognitively able neurotypical adolescent controls (NT-A, n?=?37) and younger neurotypical children (NT-C, n?=?27) to assess potential developmental delays. In addition to a classic measure of peak amplitude, we calculated a continuous measure of intra-class correlation (ICC) between each adolescent participant's AEP and the age-normative, average AEP waveforms calculated from NT-C and NT-A to study differences in signal morphology. We found that peak amplitudes of neural responses were significantly smaller in autistic adolescents compared to NT-A. We also found that the AEP morphology of autistic adolescents looked more like NT-A peers than NT-C but was still significantly different from NT-A AEP waveforms. Results suggest that AEPs of autistic adolescents present differently from NTs, regardless of age, and differences cannot be accounted for by developmental delay. Nonverbal intelligence significantly predicted how closely each adolescent's AEP resembled the age-normed waveform. These results support an evolving theory that the degree of disruption in early neural responses to low-level inputs is reflected in the severity of intellectual impairments in autism. En ligne : https://doi.org/10.1002/aur.3003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=513