Acquisition of voice onset time in toddlers at high and low risk for autism spectrum disorder / Karen CHENAUSKY in Autism Research, 10-7 (July 2017)  

Public ISBD [article]  inAutism Research > 10-7 (July 2017) . - p.1269-1279 Titre : Acquisition of voice onset time in toddlers at high and low risk for autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Karen CHENAUSKY, Auteur ; Helen TAGER-FLUSBERG, Auteur Article en page(s) : p.1269-1279 Langues : Anglais (eng) Mots-clés : autism  speech development  phonological development  stop consonants  broader autism phenotype  voice onset time Index. décimale : PER Périodiques Résumé : Although language delay is common in autism spectrum disorder (ASD), research is equivocal on whether speech development is affected. We used acoustic methods to investigate the existence of sub-perceptual differences in the speech of toddlers who developed ASD. Development of the distinction between b and p was prospectively tracked in 22 toddlers at low risk for ASD (LRC), 22 at high risk for ASD without ASD (HRA?), and 11 at high risk for ASD who were diagnosed with ASD at 36 months (HRA+). Voice onset time (VOT), the main acoustic difference between b and p, was measured from spontaneously produced words at 18, 24, and 36 months. Number of words, number of tokens (instances) of syllable-initial b and p produced, error rates, language scores, and motor ability were also assessed. All groups' mean language scores were within the average range or slightly higher. No between-group differences were found in number of words, b's, p's, or errors produced; or in mean or standard deviation of VOT. Binary logistic regression showed that only diagnostic status, not language score, motor ability, number of words, number of b's and p's, or number of errors significantly predicted whether a toddler produced acoustically distinct b and p populations at 36 months. HRA+ toddlers were significantly less likely to produce acoustically distinct b's and p's at 36 months, which may indicate that the HRA+ group may be using different strategies to produce this distinction. En ligne : http://dx.doi.org/10.1002/aur.1775 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=309 [article] Acquisition of voice onset time in toddlers at high and low risk for autism spectrum disorder [Texte imprimé et/ou numérique] / Karen CHENAUSKY, Auteur ; Helen TAGER-FLUSBERG, Auteur . - p.1269-1279. Langues : Anglais (eng) in Autism Research > 10-7 (July 2017) . - p.1269-1279 Mots-clés : autism  speech development  phonological development  stop consonants  broader autism phenotype  voice onset time Index. décimale : PER Périodiques Résumé : Although language delay is common in autism spectrum disorder (ASD), research is equivocal on whether speech development is affected. We used acoustic methods to investigate the existence of sub-perceptual differences in the speech of toddlers who developed ASD. Development of the distinction between b and p was prospectively tracked in 22 toddlers at low risk for ASD (LRC), 22 at high risk for ASD without ASD (HRA?), and 11 at high risk for ASD who were diagnosed with ASD at 36 months (HRA+). Voice onset time (VOT), the main acoustic difference between b and p, was measured from spontaneously produced words at 18, 24, and 36 months. Number of words, number of tokens (instances) of syllable-initial b and p produced, error rates, language scores, and motor ability were also assessed. All groups' mean language scores were within the average range or slightly higher. No between-group differences were found in number of words, b's, p's, or errors produced; or in mean or standard deviation of VOT. Binary logistic regression showed that only diagnostic status, not language score, motor ability, number of words, number of b's and p's, or number of errors significantly predicted whether a toddler produced acoustically distinct b and p populations at 36 months. HRA+ toddlers were significantly less likely to produce acoustically distinct b's and p's at 36 months, which may indicate that the HRA+ group may be using different strategies to produce this distinction. En ligne : http://dx.doi.org/10.1002/aur.1775 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=309

Alpha Asymmetry in Infants at Risk for Autism Spectrum Disorders / Laurel GABARD-DURNAM in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.473-480 Titre : Alpha Asymmetry in Infants at Risk for Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Laurel GABARD-DURNAM, Auteur ; Adrienne L. TIERNEY, Auteur ; Vanessa VOGEL-FARLEY, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur Article en page(s) : p.473-480 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Infant siblings  Electroencephalography  Frontal alpha asymmetry  Endophenotype Index. décimale : PER Périodiques Résumé : An emerging focus of research on autism spectrum disorder (ASD) targets the identification of early-developing ASD endophenotypes using infant siblings of affected children. One potential neural endophenotype is resting frontal electroencephalogram (EEG) alpha asymmetry, a metric of hemispheric organization. Here, we examined the development of frontal EEG alpha asymmetry in ASD high-risk and low-risk infant populations. Our findings demonstrate that low and high-risk infants show different patterns of alpha asymmetry at 6 months of age and opposite growth trajectories in asymmetry over the following 12 months. These results support the candidacy of alpha asymmetry as an early neural ASD endophenotype. En ligne : http://dx.doi.org/10.1007/s10803-013-1926-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Alpha Asymmetry in Infants at Risk for Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Laurel GABARD-DURNAM, Auteur ; Adrienne L. TIERNEY, Auteur ; Vanessa VOGEL-FARLEY, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur . - p.473-480. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.473-480 Mots-clés : Autism spectrum disorder  Infant siblings  Electroencephalography  Frontal alpha asymmetry  Endophenotype Index. décimale : PER Périodiques Résumé : An emerging focus of research on autism spectrum disorder (ASD) targets the identification of early-developing ASD endophenotypes using infant siblings of affected children. One potential neural endophenotype is resting frontal electroencephalogram (EEG) alpha asymmetry, a metric of hemispheric organization. Here, we examined the development of frontal EEG alpha asymmetry in ASD high-risk and low-risk infant populations. Our findings demonstrate that low and high-risk infants show different patterns of alpha asymmetry at 6 months of age and opposite growth trajectories in asymmetry over the following 12 months. These results support the candidacy of alpha asymmetry as an early neural ASD endophenotype. En ligne : http://dx.doi.org/10.1007/s10803-013-1926-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

An experimental study of word learning in minimally verbal children and adolescents with autism spectrum disorder / Robert M. JOSEPH in Autism & Developmental Language Impairments, 4 (January-December 2019)  

Public ISBD [article]  inAutism & Developmental Language Impairments > 4 (January-December 2019) Titre : An experimental study of word learning in minimally verbal children and adolescents with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Robert M. JOSEPH, Auteur ; Daniela Plesa SKWERER, Auteur ; Brady EGGLESTON, Auteur ; Steven R. MEYER, Auteur ; Helen TAGER-FLUSBERG, Auteur Index. décimale : PER Périodiques Résumé : Background and aimsWhen children hear a novel word, they tend to associate it with a novel rather than a familiar object. The ability to map a novel word to its corresponding referent is thought to depend, at least in part, on language-learning strategies, such as mutual exclusivity and lexical contrast. Although the importance of word learning strategies has been broadly investigated in typically developing children as well as younger children with autism spectrum disorder, who are usually language delayed, there is a paucity of research on such strategies and their role in language learning in school-age children and adolescents with autism spectrum disorder who have failed to develop fluent speech. In this study, we examined the ability of minimally verbal children and adolescents with autism spectrum disorder to learn and retain novel words in an experimental task, as well as the cognitive, language, and social correlates of these abilities. We were primarily interested in the characteristics that differentiated between three subgroups of participants: those unable to use word learning strategies, particularly mutual exclusivity, to learn novel words; those able to learn novel words over several exposure trials but not able retain them; and those able to retain the words they learned.MethodsParticipants were 29 minimally verbal individuals with autism spectrum disorder from 5 to 17 years of age. Participants completed a computerized touchscreen novel-word-learning procedure followed by assessments of immediate retention and of delayed retention, two hours later. Participants were grouped according to whether they passed/failed at least 7 of 8 (binomial p? En ligne : https://doi.org/10.1177/2396941519834717 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402 [article] An experimental study of word learning in minimally verbal children and adolescents with autism spectrum disorder [Texte imprimé et/ou numérique] / Robert M. JOSEPH, Auteur ; Daniela Plesa SKWERER, Auteur ; Brady EGGLESTON, Auteur ; Steven R. MEYER, Auteur ; Helen TAGER-FLUSBERG, Auteur. in Autism & Developmental Language Impairments > 4 (January-December 2019) Index. décimale : PER Périodiques Résumé : Background and aimsWhen children hear a novel word, they tend to associate it with a novel rather than a familiar object. The ability to map a novel word to its corresponding referent is thought to depend, at least in part, on language-learning strategies, such as mutual exclusivity and lexical contrast. Although the importance of word learning strategies has been broadly investigated in typically developing children as well as younger children with autism spectrum disorder, who are usually language delayed, there is a paucity of research on such strategies and their role in language learning in school-age children and adolescents with autism spectrum disorder who have failed to develop fluent speech. In this study, we examined the ability of minimally verbal children and adolescents with autism spectrum disorder to learn and retain novel words in an experimental task, as well as the cognitive, language, and social correlates of these abilities. We were primarily interested in the characteristics that differentiated between three subgroups of participants: those unable to use word learning strategies, particularly mutual exclusivity, to learn novel words; those able to learn novel words over several exposure trials but not able retain them; and those able to retain the words they learned.MethodsParticipants were 29 minimally verbal individuals with autism spectrum disorder from 5 to 17 years of age. Participants completed a computerized touchscreen novel-word-learning procedure followed by assessments of immediate retention and of delayed retention, two hours later. Participants were grouped according to whether they passed/failed at least 7 of 8 (binomial p? En ligne : https://doi.org/10.1177/2396941519834717 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402

Assessing the Minimally Verbal School-Aged Child With Autism Spectrum Disorder / Connie KASARI in Autism Research, 6-6 (December 2013)  

Public ISBD [article]  inAutism Research > 6-6 (December 2013) . - p.479-493 Titre : Assessing the Minimally Verbal School-Aged Child With Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Connie KASARI, Auteur ; Nancy C. BRADY, Auteur ; Catherine LORD, Auteur ; Helen TAGER-FLUSBERG, Auteur Année de publication : 2013 Article en page(s) : p.479-493 Langues : Anglais (eng) Mots-clés : minimally verbal  school-aged children  assessment  communication Index. décimale : PER Périodiques Résumé : This paper addresses the issue of assessing communication, language, and associated cognitive and behavioral abilities of minimally verbal children with autism spectrum disorder (ASD), presenting a summary of a year-long series of meetings held by a group of experts in the field of ASD and National Institutes of Health staff. In this paper, our goals were to first define the population and then present general guidelines for optimizing assessment sessions for this challenging population. We then summarize the available measures that can be used across a variety of behavioral domains that are most directly relevant to developing language skills, including oral motor skills, vocal repertoire, receptive and expressive language, imitation, intentional communication, play, social behavior, repetitive and sensory behaviors, and nonverbal cognition. We conclude with a discussion of some of the limitations in the available measures and highlight recommendations for future research in this area. En ligne : http://dx.doi.org/10.1002/aur.1334 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221 [article] Assessing the Minimally Verbal School-Aged Child With Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Connie KASARI, Auteur ; Nancy C. BRADY, Auteur ; Catherine LORD, Auteur ; Helen TAGER-FLUSBERG, Auteur . - 2013 . - p.479-493. Langues : Anglais (eng) in Autism Research > 6-6 (December 2013) . - p.479-493 Mots-clés : minimally verbal  school-aged children  assessment  communication Index. décimale : PER Périodiques Résumé : This paper addresses the issue of assessing communication, language, and associated cognitive and behavioral abilities of minimally verbal children with autism spectrum disorder (ASD), presenting a summary of a year-long series of meetings held by a group of experts in the field of ASD and National Institutes of Health staff. In this paper, our goals were to first define the population and then present general guidelines for optimizing assessment sessions for this challenging population. We then summarize the available measures that can be used across a variety of behavioral domains that are most directly relevant to developing language skills, including oral motor skills, vocal repertoire, receptive and expressive language, imitation, intentional communication, play, social behavior, repetitive and sensory behaviors, and nonverbal cognition. We conclude with a discussion of some of the limitations in the available measures and highlight recommendations for future research in this area. En ligne : http://dx.doi.org/10.1002/aur.1334 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221

Atypical Hemispheric Specialization for Faces in Infants at Risk for Autism Spectrum Disorder / Brandon KEEHN in Autism Research, 8-2 (April 2015)  

Public ISBD [article]  inAutism Research > 8-2 (April 2015) . - p.187-198 Titre : Atypical Hemispheric Specialization for Faces in Infants at Risk for Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Brandon KEEHN, Auteur ; Vanessa VOGEL-FARLEY, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur Article en page(s) : p.187-198 Langues : Anglais (eng) Mots-clés : autism  EEG coherence  face processing  hemispheric specialization  endophenotype  gamma  infancy Index. décimale : PER Périodiques Résumé : Among the many experimental findings that tend to distinguish those with and without autism spectrum disorder (ASD) are face processing deficits, reduced hemispheric specialization, and atypical neurostructural and functional connectivity. To investigate the earliest manifestations of these features, we examined lateralization of event-related gamma-band coherence to faces during the first year of life in infants at high risk for autism (HRA; defined as having an older sibling with ASD) who were compared with low-risk comparison (LRC) infants, defined as having no family history of ASD. Participants included 49 HRA and 46 LRC infants who contributed a total of 127 data sets at 6 and 12 months. Electroencephalography was recorded while infants viewed images of familiar/unfamiliar faces. Event-related gamma-band (30–50?Hz) phase coherence between anterior–posterior electrode pairs for left and right hemispheres was computed. Developmental trajectories for lateralization of intra-hemispheric coherence were significantly different in HRA and LRC infants: by 12 months, HRA infants showed significantly greater leftward lateralization compared with LRC infants who showed rightward lateralization. Preliminary results indicate that infants who later met criteria for ASD were those that showed the greatest leftward lateralization. HRA infants demonstrate an aberrant pattern of leftward lateralization of intra-hemispheric coherence by the end of the first year of life, suggesting that the network specialized for face processing may develop atypically. Further, infants with the greatest leftward asymmetry at 12 months where those that later met criteria for ASD, providing support to the growing body of evidence that atypical hemispheric specialization may be an early neurobiological marker for ASD. En ligne : http://dx.doi.org/10.1002/aur.1438 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=256 [article] Atypical Hemispheric Specialization for Faces in Infants at Risk for Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Brandon KEEHN, Auteur ; Vanessa VOGEL-FARLEY, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur . - p.187-198. Langues : Anglais (eng) in Autism Research > 8-2 (April 2015) . - p.187-198 Mots-clés : autism  EEG coherence  face processing  hemispheric specialization  endophenotype  gamma  infancy Index. décimale : PER Périodiques Résumé : Among the many experimental findings that tend to distinguish those with and without autism spectrum disorder (ASD) are face processing deficits, reduced hemispheric specialization, and atypical neurostructural and functional connectivity. To investigate the earliest manifestations of these features, we examined lateralization of event-related gamma-band coherence to faces during the first year of life in infants at high risk for autism (HRA; defined as having an older sibling with ASD) who were compared with low-risk comparison (LRC) infants, defined as having no family history of ASD. Participants included 49 HRA and 46 LRC infants who contributed a total of 127 data sets at 6 and 12 months. Electroencephalography was recorded while infants viewed images of familiar/unfamiliar faces. Event-related gamma-band (30–50?Hz) phase coherence between anterior–posterior electrode pairs for left and right hemispheres was computed. Developmental trajectories for lateralization of intra-hemispheric coherence were significantly different in HRA and LRC infants: by 12 months, HRA infants showed significantly greater leftward lateralization compared with LRC infants who showed rightward lateralization. Preliminary results indicate that infants who later met criteria for ASD were those that showed the greatest leftward lateralization. HRA infants demonstrate an aberrant pattern of leftward lateralization of intra-hemispheric coherence by the end of the first year of life, suggesting that the network specialized for face processing may develop atypically. Further, infants with the greatest leftward asymmetry at 12 months where those that later met criteria for ASD, providing support to the growing body of evidence that atypical hemispheric specialization may be an early neurobiological marker for ASD. En ligne : http://dx.doi.org/10.1002/aur.1438 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=256

Atypical Perception of Sounds in Minimally and Low Verbal Children and Adolescents With Autism as Revealed by Behavioral and Neural Measures / Sophie SCHWARTZ in Autism Research, 13-10 (October 2020)  

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Atypical Response to Caregiver Touch in Infants at High Risk for Autism Spectrum Disorder / Girija KADLASKAR in Journal of Autism and Developmental Disorders, 49-7 (July 2019)  

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Auditory evoked potentials in adolescents with autism: An investigation of brain development, intellectual impairment, and neural encoding / Sophie SCHWARTZ in Autism Research, 16-10 (October 2023)  

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Autism screening and diagnosis in low resource settings: Challenges and opportunities to enhance research and services worldwide / Maureen S. DURKIN in Autism Research, 8-5 (October 2015)  

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Autisme infantile / Helen TAGER-FLUSBERG

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Behavioral predictors of improved speech output in minimally verbal children with autism / Karen CHENAUSKY in Autism Research, 11-10 (October 2018)  

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Brief Report: Parents' Declarative Use of Deictic Gestures Predict Vocabulary Development in Infants at High and Low Risk for Autism Spectrum Disorder / B. CHOI in Journal of Autism and Developmental Disorders, 52-2 (February 2022)  

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Caregiver Touch-Speech Communication and Infant Responses in 12-Month-Olds at High Risk for Autism Spectrum Disorder / Girija KADLASKAR in Journal of Autism and Developmental Disorders, 50-3 (March 2020)  

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Cerebellum, Language, and Cognition in Autism and Specific Language Impairment / Steven M. HODGE in Journal of Autism and Developmental Disorders, 40-3 (March 2010)  

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Commentary: Measuring Language Change Through Natural Language Samples / Mihaela D. BAROKOVA in Journal of Autism and Developmental Disorders, 50-7 (July 2020)  

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