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Food-related Neural Circuitry in Prader-Willi Syndrome: Response to High- Versus Low-calorie Foods / Anastasia DIMITROPOULOS in Journal of Autism and Developmental Disorders, 38-9 (October 2008)
[article]
Titre : Food-related Neural Circuitry in Prader-Willi Syndrome: Response to High- Versus Low-calorie Foods Type de document : Texte imprimé et/ou numérique Auteurs : Anastasia DIMITROPOULOS, Auteur ; Robert T. SCHULTZ, Auteur Année de publication : 2008 Article en page(s) : p.1642-1653 Langues : Anglais (eng) Mots-clés : Prader-Willi-syndrome fMRI Hypothalamus Food-related Genetic Index. décimale : PER Périodiques Résumé : Prader-Willi syndrome (PWS) is a neurodevelopmental disorder characterized by hyperphagia and food preoccupations. Although dysfunction of the hypothalamus likely has a critical role in hyperphagia, it is only one of several regions involved in the regulation of eating. The purpose of this research was to examine food-related neural circuitry using functional magnetic resonance imaging in individuals with PWS and matched controls. Individuals with PWS showed increased activation in neural circuitry known to mediate hunger and motivation (hypothalamus, OFC) in response to high- versus low-calorie foods and in comparison to controls. This suggests neural circuitry for PWS is abnormally activated during hunger, particularly for high-calorie foods, and may mediate abnormally strong hunger states, therefore playing a significant role in PWS-induced hyperphagia. En ligne : http://dx.doi.org/10.1007/s10803-008-0546-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=604
in Journal of Autism and Developmental Disorders > 38-9 (October 2008) . - p.1642-1653[article] Food-related Neural Circuitry in Prader-Willi Syndrome: Response to High- Versus Low-calorie Foods [Texte imprimé et/ou numérique] / Anastasia DIMITROPOULOS, Auteur ; Robert T. SCHULTZ, Auteur . - 2008 . - p.1642-1653.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 38-9 (October 2008) . - p.1642-1653
Mots-clés : Prader-Willi-syndrome fMRI Hypothalamus Food-related Genetic Index. décimale : PER Périodiques Résumé : Prader-Willi syndrome (PWS) is a neurodevelopmental disorder characterized by hyperphagia and food preoccupations. Although dysfunction of the hypothalamus likely has a critical role in hyperphagia, it is only one of several regions involved in the regulation of eating. The purpose of this research was to examine food-related neural circuitry using functional magnetic resonance imaging in individuals with PWS and matched controls. Individuals with PWS showed increased activation in neural circuitry known to mediate hunger and motivation (hypothalamus, OFC) in response to high- versus low-calorie foods and in comparison to controls. This suggests neural circuitry for PWS is abnormally activated during hunger, particularly for high-calorie foods, and may mediate abnormally strong hunger states, therefore playing a significant role in PWS-induced hyperphagia. En ligne : http://dx.doi.org/10.1007/s10803-008-0546-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=604