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Dissociation of Cross-Sectional Trajectories for Verbal and Visuo-Spatial Working Memory Development in Rubinstein-Taybi Syndrome / Jane WAITE in Journal of Autism and Developmental Disorders, 46-6 (June 2016)

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inJournal of Autism and Developmental Disorders > 46-6 (June 2016) . - p.2064-2071

Titre :	Dissociation of Cross-Sectional Trajectories for Verbal and Visuo-Spatial Working Memory Development in Rubinstein-Taybi Syndrome
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Jane WAITE, Auteur ; Sarah R. BECK, Auteur ; Mary HEALD, Auteur ; Laurie POWIS, Auteur ; Chris OLIVER, Auteur
Article en page(s) :	p.2064-2071
Langues :	Anglais (eng)
Mots-clés :	Working memory Short-term memory Rubinstein–Taybi syndrome Typically developing children Dissociation
Index. décimale :	PER Périodiques
Résumé :	Working memory (WM) impairments might amplify behavioural difference in genetic syndromes. Murine models of Rubinstein–Taybi syndrome (RTS) evidence memory impairments but there is limited research on memory in RTS. Individuals with RTS and typically developing children completed WM tasks, with participants with RTS completing an IQ assessment and parents/carers completing the Vineland Adaptive Behavior Scales. A cross-sectional trajectory analysis was conducted. There were significant WM span deficits in RTS relative to mental age. Verbal WM span was positively associated with mental age; however, this was not observed for visuo-spatial span. There is a dissociation between WM domains in RTS. Individuals may have difficulties with tasks relying on WM span, above difficulties predicted by overall ability.
En ligne :	http://dx.doi.org/10.1007/s10803-016-2736-2
Permalink :	http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2889

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