[article]
Titre : |
Brief Report: Can a Composite Heart Rate Variability Biomarker Shed New Insights About Autism Spectrum Disorder in School-Aged Children? |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
Martin G. FRASCH, Auteur ; Chao SHEN, Auteur ; Hau-Tieng WU, Auteur ; Alexander MUELLER, Auteur ; Emily NEUHAUS, Auteur ; Raphael BERNIER, Auteur ; Dana KAMARA, Auteur ; Theodore P. BEAUCHAINE, Auteur |
Article en page(s) : |
p.346-356 |
Langues : |
Anglais (eng) |
Mots-clés : |
Biomarker Electrocardiogram Heart rate variability |
Index. décimale : |
PER Périodiques |
Résumé : |
Several studies show altered heart rate variability (HRV) in autism spectrum disorder (ASD), but findings are neither universal nor specific to ASD. We apply a set of linear and nonlinear HRV measures-including phase rectified signal averaging-to segments of resting ECG data collected from school-age children with ASD, age-matched typically developing controls, and children with other psychiatric conditions characterized by altered HRV (conduct disorder, depression). We use machine learning to identify time, frequency, and geometric signal-analytical domains that are specific to ASD (receiver operating curve area?=?0.89). This is the first study to differentiate children with ASD from other disorders characterized by altered HRV. Despite a small cohort and lack of external validation, results warrant larger prospective studies. |
En ligne : |
http://dx.doi.org/10.1007/s10803-020-04467-7 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=438 |
in Journal of Autism and Developmental Disorders > 51-1 (January 2021) . - p.346-356
[article] Brief Report: Can a Composite Heart Rate Variability Biomarker Shed New Insights About Autism Spectrum Disorder in School-Aged Children? [Texte imprimé et/ou numérique] / Martin G. FRASCH, Auteur ; Chao SHEN, Auteur ; Hau-Tieng WU, Auteur ; Alexander MUELLER, Auteur ; Emily NEUHAUS, Auteur ; Raphael BERNIER, Auteur ; Dana KAMARA, Auteur ; Theodore P. BEAUCHAINE, Auteur . - p.346-356. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 51-1 (January 2021) . - p.346-356
Mots-clés : |
Biomarker Electrocardiogram Heart rate variability |
Index. décimale : |
PER Périodiques |
Résumé : |
Several studies show altered heart rate variability (HRV) in autism spectrum disorder (ASD), but findings are neither universal nor specific to ASD. We apply a set of linear and nonlinear HRV measures-including phase rectified signal averaging-to segments of resting ECG data collected from school-age children with ASD, age-matched typically developing controls, and children with other psychiatric conditions characterized by altered HRV (conduct disorder, depression). We use machine learning to identify time, frequency, and geometric signal-analytical domains that are specific to ASD (receiver operating curve area?=?0.89). This is the first study to differentiate children with ASD from other disorders characterized by altered HRV. Despite a small cohort and lack of external validation, results warrant larger prospective studies. |
En ligne : |
http://dx.doi.org/10.1007/s10803-020-04467-7 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=438 |
|