Aetiological overlap between anxiety and attention deficit hyperactivity symptom dimensions in adolescence / Giorgia MICHELINI in Journal of Child Psychology and Psychiatry, 56-4 (April 2015)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 56-4 (April 2015) . - p.423-431 Titre : Aetiological overlap between anxiety and attention deficit hyperactivity symptom dimensions in adolescence Type de document : texte imprimé Auteurs : Giorgia MICHELINI, Auteur ; Thalia C. ELEY, Auteur ; Alice M. GREGORY, Auteur ; Tom A. MCADAMS, Auteur Article en page(s) : p.423-431 Langues : Anglais (eng) Mots-clés : Anxiety  ADH problems  genetics  twins  adolescence Index. décimale : PER Périodiques Résumé : Background Anxiety and attention-deficit/hyperactivity (ADH) problems are common in adolescence, often co-occur, and are characterised by high heterogeneity in their phenotypic expressions. Although it is known that anxiety and ADH problems correlate, the relationships between subtypes of anxiety and ADH problems have been scarcely investigated. Methods Using a large population sample of adolescent twins and siblings we explored the phenotypic and aetiological association between anxiety subtypes (panic/agoraphobia, separation anxiety, social anxiety, physical injury fears, obsessive-compulsive symptoms and generalised anxiety) and the two ADH dimensions (attention problems and hyperactivity/impulsivity). Both phenotypes were assessed using self-report questionnaires. Results The association between ADH problems and anxiety could be entirely attributed to attention problems, not hyperactivity/impulsivity. Most of the correlations between anxiety subtypes and attention problems showed an approximately equal role of genetic and nonshared environmental factors. Conclusions The high heterogeneity within anxiety and ADH problems should be taken into account in order to better understand comorbidity between them. En ligne : http://dx.doi.org/10.1111/jcpp.12318 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 [article] Aetiological overlap between anxiety and attention deficit hyperactivity symptom dimensions in adolescence [texte imprimé] / Giorgia MICHELINI, Auteur ; Thalia C. ELEY, Auteur ; Alice M. GREGORY, Auteur ; Tom A. MCADAMS, Auteur . - p.423-431. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 56-4 (April 2015) . - p.423-431 Mots-clés : Anxiety  ADH problems  genetics  twins  adolescence Index. décimale : PER Périodiques Résumé : Background Anxiety and attention-deficit/hyperactivity (ADH) problems are common in adolescence, often co-occur, and are characterised by high heterogeneity in their phenotypic expressions. Although it is known that anxiety and ADH problems correlate, the relationships between subtypes of anxiety and ADH problems have been scarcely investigated. Methods Using a large population sample of adolescent twins and siblings we explored the phenotypic and aetiological association between anxiety subtypes (panic/agoraphobia, separation anxiety, social anxiety, physical injury fears, obsessive-compulsive symptoms and generalised anxiety) and the two ADH dimensions (attention problems and hyperactivity/impulsivity). Both phenotypes were assessed using self-report questionnaires. Results The association between ADH problems and anxiety could be entirely attributed to attention problems, not hyperactivity/impulsivity. Most of the correlations between anxiety subtypes and attention problems showed an approximately equal role of genetic and nonshared environmental factors. Conclusions The high heterogeneity within anxiety and ADH problems should be taken into account in order to better understand comorbidity between them. En ligne : http://dx.doi.org/10.1111/jcpp.12318 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260

Aetiology of shame and its association with adolescent depression and anxiety: results from a prospective twin and sibling study / M. NIKOLIĆ in Journal of Child Psychology and Psychiatry, 63-1 (January 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-1 (January 2022) . - p.99-108 Titre : Aetiology of shame and its association with adolescent depression and anxiety: results from a prospective twin and sibling study Type de document : texte imprimé Auteurs : M. NIKOLIĆ, Auteur ; Laurie J. HANNIGAN, Auteur ; Georgina KREBS, Auteur ; A. STERNE, Auteur ; Alice M. GREGORY, Auteur ; Thalia C. ELEY, Auteur Article en page(s) : p.99-108 Langues : Anglais (eng) Mots-clés : Adolescent  Anxiety/epidemiology/genetics  Child  Depression/epidemiology/genetics  Female  Humans  Male  Prospective Studies  Shame  Siblings  Young Adult  Adolescence  anxiety  depression  twins Index. décimale : PER Périodiques Résumé : BACKGROUND: Shame is considered a maladaptive self-conscious emotion that commonly co-occurs alongside depression and anxiety. Little is known, however, about the aetiology of shame and its associations with depression and anxiety. We estimated, for the first time, genetic and environmental influences on shame and on its associations with depression and anxiety in adolescence. METHODS: The sample was twin and sibling pairs from the Genesis 1219 Study (Time 1, N = 2,685; males 42.8%, M(age)  = 14.95, SD = 1.67, age range: 12-21; Time 2, N = 1618; males 39.7%, M(age)  = 16.97, SD = 1.64, age range: 14-23). Participants completed validated questionnaires to measure shame (at Time 1), depression and anxiety (at Times 1 and 2). RESULTS: Shame was moderately to strongly associated with concurrent depression and anxiety. Prospectively, shame was significantly associated with an increase in depression, but not anxiety. Genetic analyses revealed that shame was moderately heritable with substantial nonshared environmental influence. The associations between shame and concurrent depression and anxiety were primarily accounted for by overlapping genetic influences. Prospectively, the association between shame and later depression was primarily accounted for by genetic and nonshared environmental influences shared with earlier depression. The unique association between shame and later depression was mostly explained by common nonshared environmental influences. CONCLUSIONS: The findings offer novel evidence regarding aetiology of shame-although moderately heritable, shame in adolescents may also result from nonshared environmental factors. Genetic and nonshared environmental influences contribute to the co-occurrence of shame with depression and anxiety. En ligne : http://dx.doi.org/10.1111/jcpp.13465 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 [article] Aetiology of shame and its association with adolescent depression and anxiety: results from a prospective twin and sibling study [texte imprimé] / M. NIKOLIĆ, Auteur ; Laurie J. HANNIGAN, Auteur ; Georgina KREBS, Auteur ; A. STERNE, Auteur ; Alice M. GREGORY, Auteur ; Thalia C. ELEY, Auteur . - p.99-108. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-1 (January 2022) . - p.99-108 Mots-clés : Adolescent  Anxiety/epidemiology/genetics  Child  Depression/epidemiology/genetics  Female  Humans  Male  Prospective Studies  Shame  Siblings  Young Adult  Adolescence  anxiety  depression  twins Index. décimale : PER Périodiques Résumé : BACKGROUND: Shame is considered a maladaptive self-conscious emotion that commonly co-occurs alongside depression and anxiety. Little is known, however, about the aetiology of shame and its associations with depression and anxiety. We estimated, for the first time, genetic and environmental influences on shame and on its associations with depression and anxiety in adolescence. METHODS: The sample was twin and sibling pairs from the Genesis 1219 Study (Time 1, N = 2,685; males 42.8%, M(age)  = 14.95, SD = 1.67, age range: 12-21; Time 2, N = 1618; males 39.7%, M(age)  = 16.97, SD = 1.64, age range: 14-23). Participants completed validated questionnaires to measure shame (at Time 1), depression and anxiety (at Times 1 and 2). RESULTS: Shame was moderately to strongly associated with concurrent depression and anxiety. Prospectively, shame was significantly associated with an increase in depression, but not anxiety. Genetic analyses revealed that shame was moderately heritable with substantial nonshared environmental influence. The associations between shame and concurrent depression and anxiety were primarily accounted for by overlapping genetic influences. Prospectively, the association between shame and later depression was primarily accounted for by genetic and nonshared environmental influences shared with earlier depression. The unique association between shame and later depression was mostly explained by common nonshared environmental influences. CONCLUSIONS: The findings offer novel evidence regarding aetiology of shame-although moderately heritable, shame in adolescents may also result from nonshared environmental factors. Genetic and nonshared environmental influences contribute to the co-occurrence of shame with depression and anxiety. En ligne : http://dx.doi.org/10.1111/jcpp.13465 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456

Anxiety in the family: a genetically informed analysis of transactional associations between mother, father and child anxiety symptoms / Yasmin I. AHMADZADEH in Journal of Child Psychology and Psychiatry, 60-12 (December 2019)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 60-12 (December 2019) . - p.1269-1277 Titre : Anxiety in the family: a genetically informed analysis of transactional associations between mother, father and child anxiety symptoms Type de document : texte imprimé Auteurs : Yasmin I. AHMADZADEH, Auteur ; Thalia C. ELEY, Auteur ; Leslie D. LEVE, Auteur ; Daniel S. SHAW, Auteur ; Misaki N. NATSUAKI, Auteur ; David REISS, Auteur ; Jenae M. NEIDERHISER, Auteur ; Thomas A. MCADAMS, Auteur Article en page(s) : p.1269-1277 Langues : Anglais (eng) Mots-clés : Anxiety  genetics  longitudinal  parent-child relationships  structural equation modelling Index. décimale : PER Périodiques Résumé : BACKGROUND: Anxiety in parents is associated with anxiety in offspring, although little is known about the mechanisms underpinning these intergenerational associations. We conducted the first genetically sensitive study to simultaneously examine the effects of mother, father and child anxiety symptoms on each other over time. METHOD: Adoptive parent and child symptoms were measured at child ages 6, 7 and 8 years from 305 families involved in the Early Growth and Development Study, using a prospective adoption design. Children were adopted at birth to nonrelatives, and composite data on internalising problems within birth families were used as a proxy measure of offspring inherited risk for anxiety. Structural equation models were fitted to the data to examine prospective associations between adoptive mother, father and child symptoms, whilst accounting for individuals' symptom stability over time. RESULTS: Child anxiety symptoms at age 7 predicted adoptive mothers' anxiety symptoms at age 8. No mother-to-child or child-to-father effects were observed. These results were consistent in sensitivity analyses using only paternal offspring reports and using a second measure of child anxiety symptoms. Fathers' anxiety symptoms at child age 6 prospectively predicted child symptoms, but only when paternal offspring reports were included in the model. Composite data on birth family internalising problems were not associated with child anxiety symptoms. CONCLUSIONS: Results show environmentally mediated associations between parent and child anxiety symptoms. Results support developmental theories suggesting that child anxiety symptoms can exert influence on caregivers, and mothers and fathers may play unique roles during the development of child symptoms. Further research is needed on the role of genetic transmission associated with anxiety symptoms in biologically related families. In the meantime, researchers and clinicians should strive to include fathers in assessments and consider the effects of child symptoms on caregivers. En ligne : http://dx.doi.org/10.1111/jcpp.13068 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=412 [article] Anxiety in the family: a genetically informed analysis of transactional associations between mother, father and child anxiety symptoms [texte imprimé] / Yasmin I. AHMADZADEH, Auteur ; Thalia C. ELEY, Auteur ; Leslie D. LEVE, Auteur ; Daniel S. SHAW, Auteur ; Misaki N. NATSUAKI, Auteur ; David REISS, Auteur ; Jenae M. NEIDERHISER, Auteur ; Thomas A. MCADAMS, Auteur . - p.1269-1277. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 60-12 (December 2019) . - p.1269-1277 Mots-clés : Anxiety  genetics  longitudinal  parent-child relationships  structural equation modelling Index. décimale : PER Périodiques Résumé : BACKGROUND: Anxiety in parents is associated with anxiety in offspring, although little is known about the mechanisms underpinning these intergenerational associations. We conducted the first genetically sensitive study to simultaneously examine the effects of mother, father and child anxiety symptoms on each other over time. METHOD: Adoptive parent and child symptoms were measured at child ages 6, 7 and 8 years from 305 families involved in the Early Growth and Development Study, using a prospective adoption design. Children were adopted at birth to nonrelatives, and composite data on internalising problems within birth families were used as a proxy measure of offspring inherited risk for anxiety. Structural equation models were fitted to the data to examine prospective associations between adoptive mother, father and child symptoms, whilst accounting for individuals' symptom stability over time. RESULTS: Child anxiety symptoms at age 7 predicted adoptive mothers' anxiety symptoms at age 8. No mother-to-child or child-to-father effects were observed. These results were consistent in sensitivity analyses using only paternal offspring reports and using a second measure of child anxiety symptoms. Fathers' anxiety symptoms at child age 6 prospectively predicted child symptoms, but only when paternal offspring reports were included in the model. Composite data on birth family internalising problems were not associated with child anxiety symptoms. CONCLUSIONS: Results show environmentally mediated associations between parent and child anxiety symptoms. Results support developmental theories suggesting that child anxiety symptoms can exert influence on caregivers, and mothers and fathers may play unique roles during the development of child symptoms. Further research is needed on the role of genetic transmission associated with anxiety symptoms in biologically related families. In the meantime, researchers and clinicians should strive to include fathers in assessments and consider the effects of child symptoms on caregivers. En ligne : http://dx.doi.org/10.1111/jcpp.13068 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=412

Assessing gene–environment interactions on anxiety symptom subtypes across childhood and adolescence / Jennifer Y.F. LAU in Development and Psychopathology, 19-4 (Fall 2007)  

Public ISBD [article]  inDevelopment and Psychopathology > 19-4 (Fall 2007) . - p.1129-1146 Titre : Assessing gene–environment interactions on anxiety symptom subtypes across childhood and adolescence Type de document : texte imprimé Auteurs : Jennifer Y.F. LAU, Auteur ; Daniel S. PINE, Auteur ; Thalia C. ELEY, Auteur ; Alice M. GREGORY, Auteur ; Michelle A. GOLDWIN, Auteur Année de publication : 2007 Article en page(s) : p.1129-1146 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Consistent evidence shows both genetic and stress-related risks on child and adolescent anxiety, yet few studies have considered the degree to which genetic effects are moderated by stress (gene–environment interaction). We used longitudinal data from both a child and adolescent sample of twins to examine three novel issues on the presence of gene–environment interaction on anxiety symptoms. First, we assessed moderation of genetic risks on anxiety symptoms by negative life events in each age group. Second, by distinguishing between “stable” and “age-specific” genetic factors, we explored the continuity of gene–environment interaction across time and/or its emergence at specific ages. Third, we compared the presence of gene–environment interaction across different symptom types (general, panic, social, and separation). Genetic effects on separation anxiety symptoms in childhood (mean age = 8 years, 6 months) and panic anxiety symptoms in adolescence (mean age = 15 years) increased across independent negative life events. Shared environmental effects on separation anxiety symptoms and nonshared environmental effects on general anxiety symptoms in adolescence were also moderated by negative life events. We interpret these preliminary findings tentatively in the context of gene–environment interaction on anxiety in general, and on early separation and later panic anxiety in particular. En ligne : http://dx.doi.org/10.1017/s0954579407000582 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=182 [article] Assessing gene–environment interactions on anxiety symptom subtypes across childhood and adolescence [texte imprimé] / Jennifer Y.F. LAU, Auteur ; Daniel S. PINE, Auteur ; Thalia C. ELEY, Auteur ; Alice M. GREGORY, Auteur ; Michelle A. GOLDWIN, Auteur . - 2007 . - p.1129-1146. Langues : Anglais (eng) in Development and Psychopathology > 19-4 (Fall 2007) . - p.1129-1146 Index. décimale : PER Périodiques Résumé : Consistent evidence shows both genetic and stress-related risks on child and adolescent anxiety, yet few studies have considered the degree to which genetic effects are moderated by stress (gene–environment interaction). We used longitudinal data from both a child and adolescent sample of twins to examine three novel issues on the presence of gene–environment interaction on anxiety symptoms. First, we assessed moderation of genetic risks on anxiety symptoms by negative life events in each age group. Second, by distinguishing between “stable” and “age-specific” genetic factors, we explored the continuity of gene–environment interaction across time and/or its emergence at specific ages. Third, we compared the presence of gene–environment interaction across different symptom types (general, panic, social, and separation). Genetic effects on separation anxiety symptoms in childhood (mean age = 8 years, 6 months) and panic anxiety symptoms in adolescence (mean age = 15 years) increased across independent negative life events. Shared environmental effects on separation anxiety symptoms and nonshared environmental effects on general anxiety symptoms in adolescence were also moderated by negative life events. We interpret these preliminary findings tentatively in the context of gene–environment interaction on anxiety in general, and on early separation and later panic anxiety in particular. En ligne : http://dx.doi.org/10.1017/s0954579407000582 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=182

Associations between the parent–child relationship and adolescent self-worth: a genetically informed study of twin parents and their adolescent children / Tom A. MCADAMS in Journal of Child Psychology and Psychiatry, 58-1 (January 2017)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 58-1 (January 2017) . - p.46-54 Titre : Associations between the parent–child relationship and adolescent self-worth: a genetically informed study of twin parents and their adolescent children Type de document : texte imprimé Auteurs : Tom A. MCADAMS, Auteur ; Frühling V. RIJSDIJK, Auteur ; Jurgita NARUSYTE, Auteur ; Jody M. GANIBAN, Auteur ; David REISS, Auteur ; Erica SPOTTS, Auteur ; Jenae M. NEIDERHISER, Auteur ; Paul LICHTENSTEIN, Auteur ; Thalia C. ELEY, Auteur Article en page(s) : p.46-54 Langues : Anglais (eng) Mots-clés : Adolescence  parenting  parent–child relationships  children-of-twins  self-esteem Index. décimale : PER Périodiques Résumé : Background Low self-worth during adolescence predicts a range of emotional and behavioural problems. As such, identifying potential sources of influence on self-worth is important. Aspects of the parent–child relationship are often associated with adolescent self-worth but to date it is unclear whether such associations may be attributable to familial confounding (e.g. genetic relatedness). We set out to clarify the nature of relationships between parental expressed affection and adolescent self-worth, and parent–child closeness and adolescent self-worth. Methods We used data from the Twin and Offspring Study in Sweden, a children-of-twins sample comprising 909 adult twin pairs with adolescent children. Using these data we were able to apply structural equation models with which we could examine whether associations remained after accounting for genetic transmission. Results Results demonstrated that parent–child closeness and parental-expressed affection were both phenotypically associated with adolescent self-worth. Associations could not be attributed to genetic relatedness between parent and child. Conclusions Parent–child closeness and parental affection are associated with adolescent self-worth above and beyond effects attributable to genetic relatedness. Data were cross-sectional, so the direction of effects cannot be confirmed but findings support the notion that positive parent–child relationships increase adolescent self-worth. En ligne : http://dx.doi.org/10.1111/jcpp.12600 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 [article] Associations between the parent–child relationship and adolescent self-worth: a genetically informed study of twin parents and their adolescent children [texte imprimé] / Tom A. MCADAMS, Auteur ; Frühling V. RIJSDIJK, Auteur ; Jurgita NARUSYTE, Auteur ; Jody M. GANIBAN, Auteur ; David REISS, Auteur ; Erica SPOTTS, Auteur ; Jenae M. NEIDERHISER, Auteur ; Paul LICHTENSTEIN, Auteur ; Thalia C. ELEY, Auteur . - p.46-54. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 58-1 (January 2017) . - p.46-54 Mots-clés : Adolescence  parenting  parent–child relationships  children-of-twins  self-esteem Index. décimale : PER Périodiques Résumé : Background Low self-worth during adolescence predicts a range of emotional and behavioural problems. As such, identifying potential sources of influence on self-worth is important. Aspects of the parent–child relationship are often associated with adolescent self-worth but to date it is unclear whether such associations may be attributable to familial confounding (e.g. genetic relatedness). We set out to clarify the nature of relationships between parental expressed affection and adolescent self-worth, and parent–child closeness and adolescent self-worth. Methods We used data from the Twin and Offspring Study in Sweden, a children-of-twins sample comprising 909 adult twin pairs with adolescent children. Using these data we were able to apply structural equation models with which we could examine whether associations remained after accounting for genetic transmission. Results Results demonstrated that parent–child closeness and parental-expressed affection were both phenotypically associated with adolescent self-worth. Associations could not be attributed to genetic relatedness between parent and child. Conclusions Parent–child closeness and parental affection are associated with adolescent self-worth above and beyond effects attributable to genetic relatedness. Data were cross-sectional, so the direction of effects cannot be confirmed but findings support the notion that positive parent–child relationships increase adolescent self-worth. En ligne : http://dx.doi.org/10.1111/jcpp.12600 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298

Attentional threat avoidance and familial risk are independently associated with childhood anxiety disorders / Hannah M. BROWN in Journal of Child Psychology and Psychiatry, 54-6 (June 2013)  

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A cross-lagged twin study of emotional symptoms, social isolation and peer victimisation from early adolescence to emerging adulthood / Geneviève MORNEAU-VAILLANCOURT in Journal of Child Psychology and Psychiatry, 64-11 (November 2023)  

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Developmental change in the association between adolescent depressive symptoms and the home environment: results from a longitudinal, genetically informative investigation / Laurie J. HANNIGAN in Journal of Child Psychology and Psychiatry, 58-7 (July 2017)  

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Developmental trajectories of child and adolescent emotional problems: associations with early adult alcohol use behaviors / Tong CHEN in Journal of Child Psychology and Psychiatry, 66-1 (January 2025)  

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Disentangling gene-environment correlations and interactions on adolescent depressive symptoms / Jennifer Y.F. LAU in Journal of Child Psychology and Psychiatry, 49-2 (February 2008)  

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Does childhood anxiety evoke maternal control? A genetically informed study / Thalia C. ELEY in Journal of Child Psychology and Psychiatry, 51-7 (July 2010)  

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Editorial / Thalia C. ELEY in Journal of Child Psychology and Psychiatry, 47-7 (July 2006)  

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Editorial: ‘The time has come,’ the Walrus said, ‘To speak of many things; Of shoes and ships and sealing wax, Of cabbages and kings.’ / Thalia C. ELEY in Journal of Child Psychology and Psychiatry, 48-6 (June 2007)  

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Editorial: Work-in-progress: towards DSM-V / Thalia C. ELEY in Journal of Child Psychology and Psychiatry, 49-1 (January 2008)  

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Explaining the influence of non-shared environment (NSE) on symptoms of behaviour problems from preschool to adulthood: mind the missing NSE gap / Agnieszka GIDZIELA in Journal of Child Psychology and Psychiatry, 64-5 (May 2023)  

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