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Détail de l'auteur
Auteur Moji AGHAJANI |
Documents disponibles écrits par cet auteur (2)
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Different brain responses during empathy in autism spectrum disorders versus conduct disorder and callous-unemotional traits / Eduard T. KLAPWIJK in Journal of Child Psychology and Psychiatry, 57-6 (June 2016)
[article]
Titre : Different brain responses during empathy in autism spectrum disorders versus conduct disorder and callous-unemotional traits Type de document : Texte imprimé et/ou numérique Auteurs : Eduard T. KLAPWIJK, Auteur ; Moji AGHAJANI, Auteur ; Olivier F. COLINS, Auteur ; Godfried M. MARIJNISSEN, Auteur ; Arne POPMA, Auteur ; Natasja D. J. VAN LANG, Auteur ; Nic J. A. VAN DER WEE, Auteur ; Robert R. J. M. VERMEIREN, Auteur Article en page(s) : p.737-747 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders callous-unemotional conduct disorder emotions empathy functional magnetic resonance imaging Index. décimale : PER Périodiques Résumé : Background Deficits in empathy are reported in autism spectrum disorders (ASD) and also underlie antisocial behavior of individuals with conduct disorder and callous-unemotional traits (CD/CU+). Many studies suggest that individuals with ASD are typically impaired in cognitive aspects of empathy, and individuals with CD/CU+ typically in affective aspects. In the current study, we compared the neural correlates of cognitive and affective aspects of empathy between youth with ASD and youth with CD/CU+. Methods Functional magnetic resonance imaging (fMRI) was used to assess boys with ASD (N = 23), boys with CD/CU+ (N = 23), and typically developing (TD) boys (N = 33), aged 15–19 years. Angry and fearful faces were presented and participants were asked to either infer the emotional state from the face (other-task; emotion recognition) or to judge their own emotional response to the face (self-task; emotional resonance). Results During emotion recognition, boys with ASD showed reduced responses compared to the other groups in the ventromedial prefrontal cortex (vmPFC). During emotional resonance, the CD/CU+ and ASD groups showed reduced amygdala responses compared to the TD controls, boys with ASD showed reduced responses in bilateral hippocampus, and the CD/CU+ boys showed reduced responses in the inferior frontal gyrus (IFG) and anterior insula (AI). Conclusion Results suggest differential abnormal brain responses associated with specific aspects of empathic functioning in ASD and CD/CU+. Decreased amygdala responses in ASD and CD/CU+ might point to impaired emotion processing in both disorders, whereas reduced vmPFC responses suggest problems in processing cognitive aspects of empathy in ASD. Reduced IFG/AI responses, finally, suggest decreased emotional resonance in CD/CU+. En ligne : http://dx.doi.org/10.1111/jcpp.12498 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=289
in Journal of Child Psychology and Psychiatry > 57-6 (June 2016) . - p.737-747[article] Different brain responses during empathy in autism spectrum disorders versus conduct disorder and callous-unemotional traits [Texte imprimé et/ou numérique] / Eduard T. KLAPWIJK, Auteur ; Moji AGHAJANI, Auteur ; Olivier F. COLINS, Auteur ; Godfried M. MARIJNISSEN, Auteur ; Arne POPMA, Auteur ; Natasja D. J. VAN LANG, Auteur ; Nic J. A. VAN DER WEE, Auteur ; Robert R. J. M. VERMEIREN, Auteur . - p.737-747.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 57-6 (June 2016) . - p.737-747
Mots-clés : Autism spectrum disorders callous-unemotional conduct disorder emotions empathy functional magnetic resonance imaging Index. décimale : PER Périodiques Résumé : Background Deficits in empathy are reported in autism spectrum disorders (ASD) and also underlie antisocial behavior of individuals with conduct disorder and callous-unemotional traits (CD/CU+). Many studies suggest that individuals with ASD are typically impaired in cognitive aspects of empathy, and individuals with CD/CU+ typically in affective aspects. In the current study, we compared the neural correlates of cognitive and affective aspects of empathy between youth with ASD and youth with CD/CU+. Methods Functional magnetic resonance imaging (fMRI) was used to assess boys with ASD (N = 23), boys with CD/CU+ (N = 23), and typically developing (TD) boys (N = 33), aged 15–19 years. Angry and fearful faces were presented and participants were asked to either infer the emotional state from the face (other-task; emotion recognition) or to judge their own emotional response to the face (self-task; emotional resonance). Results During emotion recognition, boys with ASD showed reduced responses compared to the other groups in the ventromedial prefrontal cortex (vmPFC). During emotional resonance, the CD/CU+ and ASD groups showed reduced amygdala responses compared to the TD controls, boys with ASD showed reduced responses in bilateral hippocampus, and the CD/CU+ boys showed reduced responses in the inferior frontal gyrus (IFG) and anterior insula (AI). Conclusion Results suggest differential abnormal brain responses associated with specific aspects of empathic functioning in ASD and CD/CU+. Decreased amygdala responses in ASD and CD/CU+ might point to impaired emotion processing in both disorders, whereas reduced vmPFC responses suggest problems in processing cognitive aspects of empathy in ASD. Reduced IFG/AI responses, finally, suggest decreased emotional resonance in CD/CU+. En ligne : http://dx.doi.org/10.1111/jcpp.12498 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=289 Differential Fairness Decisions and Brain Responses After Expressed Emotions of Others in Boys with Autism Spectrum Disorders / Eduard T. KLAPWIJK in Journal of Autism and Developmental Disorders, 47-8 (August 2017)
[article]
Titre : Differential Fairness Decisions and Brain Responses After Expressed Emotions of Others in Boys with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Eduard T. KLAPWIJK, Auteur ; Moji AGHAJANI, Auteur ; Gert-Jan LELIEVELD, Auteur ; Natasja D. J. VAN LANG, Auteur ; Arne POPMA, Auteur ; Nic J. A. VAN DER WEE, Auteur ; Olivier F. COLINS, Auteur ; Robert R. J. M. VERMEIREN, Auteur Article en page(s) : p.2390-2400 Langues : Anglais (eng) Mots-clés : Social decision-making Autism spectrum disorders Interpersonal effects of emotions Dictator game fMRI Index. décimale : PER Périodiques Résumé : Little is known about how emotions expressed by others influence social decisions and associated brain responses in autism spectrum disorders (ASD). We investigated the neural mechanisms underlying fairness decisions in response to explicitly expressed emotions of others in boys with ASD and typically developing (TD) boys. Participants with ASD adjusted their allocation behavior in response to the emotions but reacted less unfair than TD controls in response to happiness. We also found reduced brain responses in the precental gyrus in the ASD versus TD group when receiving happy versus angry reactions and autistic traits were positively associated with activity in the postcentral gyrus. These results provide indications for a role of precentral and postcentral gyrus in social-affective difficulties in ASD. En ligne : https://doi.org/10.1007/s10803-017-3159-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=314
in Journal of Autism and Developmental Disorders > 47-8 (August 2017) . - p.2390-2400[article] Differential Fairness Decisions and Brain Responses After Expressed Emotions of Others in Boys with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Eduard T. KLAPWIJK, Auteur ; Moji AGHAJANI, Auteur ; Gert-Jan LELIEVELD, Auteur ; Natasja D. J. VAN LANG, Auteur ; Arne POPMA, Auteur ; Nic J. A. VAN DER WEE, Auteur ; Olivier F. COLINS, Auteur ; Robert R. J. M. VERMEIREN, Auteur . - p.2390-2400.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-8 (August 2017) . - p.2390-2400
Mots-clés : Social decision-making Autism spectrum disorders Interpersonal effects of emotions Dictator game fMRI Index. décimale : PER Périodiques Résumé : Little is known about how emotions expressed by others influence social decisions and associated brain responses in autism spectrum disorders (ASD). We investigated the neural mechanisms underlying fairness decisions in response to explicitly expressed emotions of others in boys with ASD and typically developing (TD) boys. Participants with ASD adjusted their allocation behavior in response to the emotions but reacted less unfair than TD controls in response to happiness. We also found reduced brain responses in the precental gyrus in the ASD versus TD group when receiving happy versus angry reactions and autistic traits were positively associated with activity in the postcentral gyrus. These results provide indications for a role of precentral and postcentral gyrus in social-affective difficulties in ASD. En ligne : https://doi.org/10.1007/s10803-017-3159-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=314