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Auteur Andrew J. O. WHITEHOUSE |
Documents disponibles écrits par cet auteur (81)
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Continuity of temperament subgroup classifications from infancy to toddlerhood in the context of early autism traits / Lacey CHETCUTI in Autism Research, 16-3 (March 2023)
[article]
Titre : Continuity of temperament subgroup classifications from infancy to toddlerhood in the context of early autism traits Type de document : Texte imprimé et/ou numérique Auteurs : Lacey CHETCUTI, Auteur ; Mirko ULJAREVI?, Auteur ; Kandice J. VARCIN, Auteur ; Maryam BOUTRUS, Auteur ; Stefanie DIMOV, Auteur ; Sarah PILLAR, Auteur ; Josephine BARBARO, Auteur ; Cheryl DISSANAYAKE, Auteur ; Jonathan GREEN, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; Kristelle HUDRY, Auteur ; the AICES TEAM, Auteur Article en page(s) : p.591-604 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Our previous cross-sectional investigation (Chetcuti et al., 2020) showed that infants with autism traits could be divided into distinct subgroups based on temperament. This longitudinal study builds on this existing work by exploring the continuity of temperament subgroup classifications and their associations with behavioral/clinical phenotypic features from infancy to toddlerhood. 103 infants (68% male) showing early signs of autism were referred to the study by community healthcare professionals and seen for assessments when aged around 12-months (Time 1), 18-months (Time 2), and 24-months (Time 3). Latent profile analysis revealed inhibited/low positive, active/negative reactive, and sociable/well-regulated subgroups at each timepoint, and a unique reactive/regulated subgroup at Time 3. Cross-tabulations indicated a significant likelihood of children having a recurrent subgroup classification from one timepoint to the next, and no apparent patterns to the movement of children who did change from one subgroup to another over time. Temperament subgroups were associated with concurrent child social-emotional functioning and autism traits, but unrelated to child age, sex, or developmental level. These findings suggest that temperament subgroup classifications might represent a reliable and very early indicator of autism characteristics and social-emotional functioning among infants/toddlers with autism traits. En ligne : https://doi.org/10.1002/aur.2874 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=498
in Autism Research > 16-3 (March 2023) . - p.591-604[article] Continuity of temperament subgroup classifications from infancy to toddlerhood in the context of early autism traits [Texte imprimé et/ou numérique] / Lacey CHETCUTI, Auteur ; Mirko ULJAREVI?, Auteur ; Kandice J. VARCIN, Auteur ; Maryam BOUTRUS, Auteur ; Stefanie DIMOV, Auteur ; Sarah PILLAR, Auteur ; Josephine BARBARO, Auteur ; Cheryl DISSANAYAKE, Auteur ; Jonathan GREEN, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; Kristelle HUDRY, Auteur ; the AICES TEAM, Auteur . - p.591-604.
Langues : Anglais (eng)
in Autism Research > 16-3 (March 2023) . - p.591-604
Index. décimale : PER Périodiques Résumé : Abstract Our previous cross-sectional investigation (Chetcuti et al., 2020) showed that infants with autism traits could be divided into distinct subgroups based on temperament. This longitudinal study builds on this existing work by exploring the continuity of temperament subgroup classifications and their associations with behavioral/clinical phenotypic features from infancy to toddlerhood. 103 infants (68% male) showing early signs of autism were referred to the study by community healthcare professionals and seen for assessments when aged around 12-months (Time 1), 18-months (Time 2), and 24-months (Time 3). Latent profile analysis revealed inhibited/low positive, active/negative reactive, and sociable/well-regulated subgroups at each timepoint, and a unique reactive/regulated subgroup at Time 3. Cross-tabulations indicated a significant likelihood of children having a recurrent subgroup classification from one timepoint to the next, and no apparent patterns to the movement of children who did change from one subgroup to another over time. Temperament subgroups were associated with concurrent child social-emotional functioning and autism traits, but unrelated to child age, sex, or developmental level. These findings suggest that temperament subgroup classifications might represent a reliable and very early indicator of autism characteristics and social-emotional functioning among infants/toddlers with autism traits. En ligne : https://doi.org/10.1002/aur.2874 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=498 Correction to: Parent-reported Early Atypical Development and Age of Diagnosis for Children with Co-occurring Autism and ADHD / Kelly CARRASCO ; Andrew J. O. WHITEHOUSE ; Hannah WADDINGTON in Journal of Autism and Developmental Disorders, 53-2 (February 2023)
[article]
Titre : Correction to: Parent-reported Early Atypical Development and Age of Diagnosis for Children with Co-occurring Autism and ADHD Type de document : Texte imprimé et/ou numérique Auteurs : Kelly CARRASCO, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; Hannah WADDINGTON, Auteur Article en page(s) : p.883-883 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1007/s10803-022-05555-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=495
in Journal of Autism and Developmental Disorders > 53-2 (February 2023) . - p.883-883[article] Correction to: Parent-reported Early Atypical Development and Age of Diagnosis for Children with Co-occurring Autism and ADHD [Texte imprimé et/ou numérique] / Kelly CARRASCO, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; Hannah WADDINGTON, Auteur . - p.883-883.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 53-2 (February 2023) . - p.883-883
Index. décimale : PER Périodiques En ligne : https://doi.org/10.1007/s10803-022-05555-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=495 Correction to: The Comprehensive Autistic Trait Inventory (CATI): development and validation of a new measure of autistic traits in the general population / M. C. W. ENGLISH in Molecular Autism, 12 (2021)
[article]
Titre : Correction to: The Comprehensive Autistic Trait Inventory (CATI): development and validation of a new measure of autistic traits in the general population Type de document : Texte imprimé et/ou numérique Auteurs : M. C. W. ENGLISH, Auteur ; G. E. GIGNAC, Auteur ; Troy A. W. VISSER, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; J. T. ENNS, Auteur ; M. T. MAYBERY, Auteur Article en page(s) : 70 p. Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1186/s13229-021-00475-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459
in Molecular Autism > 12 (2021) . - 70 p.[article] Correction to: The Comprehensive Autistic Trait Inventory (CATI): development and validation of a new measure of autistic traits in the general population [Texte imprimé et/ou numérique] / M. C. W. ENGLISH, Auteur ; G. E. GIGNAC, Auteur ; Troy A. W. VISSER, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; J. T. ENNS, Auteur ; M. T. MAYBERY, Auteur . - 70 p.
Langues : Anglais (eng)
in Molecular Autism > 12 (2021) . - 70 p.
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1186/s13229-021-00475-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459 Cytokine levels and associations with symptom severity in male and female children with autism spectrum disorder / A. MASI in Molecular Autism, 8 (2017)
[article]
Titre : Cytokine levels and associations with symptom severity in male and female children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : A. MASI, Auteur ; E. J. BREEN, Auteur ; Gail A. ALVARES, Auteur ; N. GLOZIER, Auteur ; I. B. HICKIE, Auteur ; A. HUNT, Auteur ; J. HUI, Auteur ; J. BEILBY, Auteur ; D. RAVINE, Auteur ; J. WRAY, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; A. J. GUASTELLA, Auteur Article en page(s) : 63p. Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Behavior Cytokine Pediatric Severity Index. décimale : PER Périodiques Résumé : Background: Autism spectrum disorders (ASDs) are complex, pervasive, and heterogeneous neurodevelopmental conditions with varying trajectories, significant male bias and largely unknown etiology. However, an understanding of the biological mechanisms driving pathophysiology is evolving. Immune system aberrations, as identified through cytokine profiles, are believed to have a role in ASD. Altered cytokine levels may facilitate identification of ASD subtypes as well as provide biological markers of response to effective treatments. Research exploring the relationship between cytokine profiles and ASD symptoms is, however, in its infancy. The objective of this study was to explore relationships between cytokine levels and the severity of ASD and other clinical traits. Methods: Multiplex assay techniques were used to measure levels of 27 cytokines in plasma samples from a cohort of 144 children diagnosed with ASD. Results: Overall, results showed a significant negative association between platelet-derived growth factor (PDGF)-BB, and the severity of ASD symptoms. Furthermore, a significant interaction with sex suggested a different immune profile for females compared to males. ASD symptom severity was negatively associated with levels of 4 cytokines, IL-1beta, IL-8, MIP-1beta, and VEGF, in females, but not in males. Conclusions: Results of the present study suggest that an altered cytokine response or profile is associated with the severity of ASD-related symptoms, with sex a potential modifier of this relationship. Further research in larger populations which recognizes the importance of sex comparisons and longitudinal assessments are now required to extend and further describe the role of the immune system in ASD. En ligne : http://dx.doi.org/10.1186/s13229-017-0176-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=330
in Molecular Autism > 8 (2017) . - 63p.[article] Cytokine levels and associations with symptom severity in male and female children with autism spectrum disorder [Texte imprimé et/ou numérique] / A. MASI, Auteur ; E. J. BREEN, Auteur ; Gail A. ALVARES, Auteur ; N. GLOZIER, Auteur ; I. B. HICKIE, Auteur ; A. HUNT, Auteur ; J. HUI, Auteur ; J. BEILBY, Auteur ; D. RAVINE, Auteur ; J. WRAY, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; A. J. GUASTELLA, Auteur . - 63p.
Langues : Anglais (eng)
in Molecular Autism > 8 (2017) . - 63p.
Mots-clés : Autism spectrum disorder Behavior Cytokine Pediatric Severity Index. décimale : PER Périodiques Résumé : Background: Autism spectrum disorders (ASDs) are complex, pervasive, and heterogeneous neurodevelopmental conditions with varying trajectories, significant male bias and largely unknown etiology. However, an understanding of the biological mechanisms driving pathophysiology is evolving. Immune system aberrations, as identified through cytokine profiles, are believed to have a role in ASD. Altered cytokine levels may facilitate identification of ASD subtypes as well as provide biological markers of response to effective treatments. Research exploring the relationship between cytokine profiles and ASD symptoms is, however, in its infancy. The objective of this study was to explore relationships between cytokine levels and the severity of ASD and other clinical traits. Methods: Multiplex assay techniques were used to measure levels of 27 cytokines in plasma samples from a cohort of 144 children diagnosed with ASD. Results: Overall, results showed a significant negative association between platelet-derived growth factor (PDGF)-BB, and the severity of ASD symptoms. Furthermore, a significant interaction with sex suggested a different immune profile for females compared to males. ASD symptom severity was negatively associated with levels of 4 cytokines, IL-1beta, IL-8, MIP-1beta, and VEGF, in females, but not in males. Conclusions: Results of the present study suggest that an altered cytokine response or profile is associated with the severity of ASD-related symptoms, with sex a potential modifier of this relationship. Further research in larger populations which recognizes the importance of sex comparisons and longitudinal assessments are now required to extend and further describe the role of the immune system in ASD. En ligne : http://dx.doi.org/10.1186/s13229-017-0176-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=330 Deconstructing the repetitive behaviour phenotype in autism spectrum disorder through a large population-based analysis / Mirko ULJAREVIC in Journal of Child Psychology and Psychiatry, 61-9 (September 2020)
[article]
Titre : Deconstructing the repetitive behaviour phenotype in autism spectrum disorder through a large population-based analysis Type de document : Texte imprimé et/ou numérique Auteurs : Mirko ULJAREVIC, Auteur ; Matthew N. COOPER, Auteur ; Keely BEBBINGTON, Auteur ; Emma J. GLASSON, Auteur ; Murray T. MAYBERY, Auteur ; Kandice J. VARCIN, Auteur ; Gail A. ALVARES, Auteur ; John WRAY, Auteur ; Susan R LEEKAM, Auteur ; Andrew J. O. WHITEHOUSE, Auteur Article en page(s) : p.1030-1042 Langues : Anglais (eng) Mots-clés : Repetitive behaviours autism social and communication impairments Index. décimale : PER Périodiques Résumé : OBJECTIVE: Restricted and repetitive pattern of behaviours and interests (RRB) are a cardinal feature of autism spectrum disorder (ASD), but there remains uncertainty about how these diverse behaviours vary according to individual characteristics. This study provided the largest exploration to date of the relationship between Repetitive Motor Behaviours, Rigidity/Insistence on Sameness and Circumscribed Interests with other individual characteristics in newly diagnosed individuals with ASD. METHOD: Participants (N = 3,647; 17.7% females; Mage = 6.6 years [SD = 4.7]) were part of the Western Australian (WA) Register for ASD, an independent, prospective collection of demographic and diagnostic data of newly diagnosed cases of ASD in WA. Diagnosticians rated each of the DSM-IV-TR criteria on a 4-point Likert severity scale, and here we focused on the Repetitive Motor Behaviours, Insistence on Sameness and Circumscribed Interests symptoms. RESULTS: The associations between RRB domains, indexed by Kendall's Tau, were weak, ranging from non-significant for both Circumscribed Interests and Repetitive Motor Behaviours to significant (.20) for Insistence on Sameness and Repetitive Motor Behaviours. Older age at diagnosis was significantly associated with lower Circumscribed Interests and significantly associated with higher Insistence on Sameness and Repetitive Motor Behaviours. Male sex was significantly associated with higher Repetitive Motor Behaviours but not Insistence on Sameness or Circumscribed Interests. CONCLUSIONS: The pattern of associations identified in this study provides suggestive evidence for the distinctiveness of Repetitive Motor Behaviours, Insistence on Sameness and Circumscribed Interests, highlighting the potential utility of RRB domains for stratifying the larger ASD population into smaller, more phenotypically homogeneous subgroups that can help to facilitate efforts to understand diverse ASD aetiology and inform design of future interventions. En ligne : http://dx.doi.org/10.1111/jcpp.13203 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430
in Journal of Child Psychology and Psychiatry > 61-9 (September 2020) . - p.1030-1042[article] Deconstructing the repetitive behaviour phenotype in autism spectrum disorder through a large population-based analysis [Texte imprimé et/ou numérique] / Mirko ULJAREVIC, Auteur ; Matthew N. COOPER, Auteur ; Keely BEBBINGTON, Auteur ; Emma J. GLASSON, Auteur ; Murray T. MAYBERY, Auteur ; Kandice J. VARCIN, Auteur ; Gail A. ALVARES, Auteur ; John WRAY, Auteur ; Susan R LEEKAM, Auteur ; Andrew J. O. WHITEHOUSE, Auteur . - p.1030-1042.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-9 (September 2020) . - p.1030-1042
Mots-clés : Repetitive behaviours autism social and communication impairments Index. décimale : PER Périodiques Résumé : OBJECTIVE: Restricted and repetitive pattern of behaviours and interests (RRB) are a cardinal feature of autism spectrum disorder (ASD), but there remains uncertainty about how these diverse behaviours vary according to individual characteristics. This study provided the largest exploration to date of the relationship between Repetitive Motor Behaviours, Rigidity/Insistence on Sameness and Circumscribed Interests with other individual characteristics in newly diagnosed individuals with ASD. METHOD: Participants (N = 3,647; 17.7% females; Mage = 6.6 years [SD = 4.7]) were part of the Western Australian (WA) Register for ASD, an independent, prospective collection of demographic and diagnostic data of newly diagnosed cases of ASD in WA. Diagnosticians rated each of the DSM-IV-TR criteria on a 4-point Likert severity scale, and here we focused on the Repetitive Motor Behaviours, Insistence on Sameness and Circumscribed Interests symptoms. RESULTS: The associations between RRB domains, indexed by Kendall's Tau, were weak, ranging from non-significant for both Circumscribed Interests and Repetitive Motor Behaviours to significant (.20) for Insistence on Sameness and Repetitive Motor Behaviours. Older age at diagnosis was significantly associated with lower Circumscribed Interests and significantly associated with higher Insistence on Sameness and Repetitive Motor Behaviours. Male sex was significantly associated with higher Repetitive Motor Behaviours but not Insistence on Sameness or Circumscribed Interests. CONCLUSIONS: The pattern of associations identified in this study provides suggestive evidence for the distinctiveness of Repetitive Motor Behaviours, Insistence on Sameness and Circumscribed Interests, highlighting the potential utility of RRB domains for stratifying the larger ASD population into smaller, more phenotypically homogeneous subgroups that can help to facilitate efforts to understand diverse ASD aetiology and inform design of future interventions. En ligne : http://dx.doi.org/10.1111/jcpp.13203 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430 Developmental vitamin D deficiency increases foetal exposure to testosterone / Asad Amanat ALI in Molecular Autism, 11 (2020)
PermalinkDo Children with Specific Language Impairment have a Cognitive Profile Reminiscent of Autism? A Review of the Literature / Lauren J. TAYLOR in Journal of Autism and Developmental Disorders, 42-10 (October 2012)
PermalinkDoes perinatal exposure to exogenous oxytocin influence child behavioural problems and autistic-like behaviours to 20 years of age? / A. J. GUASTELLA in Journal of Child Psychology and Psychiatry, 59-12 (December 2018)
PermalinkEarly Intervention Delivery Methods for New Zealand Children with Autism: Current Practices Versus Parental Preferences / C. WALLACE-WATKIN in Journal of Autism and Developmental Disorders, 51-9 (September 2021)
PermalinkEvidence against poor semantic encoding in individuals with autism / Andrew J. O. WHITEHOUSE in Autism, 11-3 (May 2007)
PermalinkEvidence for Distinct Cognitive Profiles in Autism Spectrum Disorders and Specific Language Impairment / Lauren J. TAYLOR in Journal of Autism and Developmental Disorders, 44-1 (January 2014)
PermalinkEvidence of a reduction over time in the behavioral severity of autistic disorder diagnoses / Andrew J. O. WHITEHOUSE in Autism Research, 10-1 (January 2017)
PermalinkExamining parent use of specific intervention techniques during a 12-week training program based on the Early Start Denver Model / Hannah WADDINGTON in Autism, 24-2 (February 2020)
PermalinkFacial asymmetry in parents of children on the autism spectrum / D. W. TAN in Autism Research, 14-11 (November 2021)
PermalinkGaps in Current Autism Research: The Thoughts of the Autism Research Editorial Board and Associate Editors / David G. AMARAL in Autism Research, 12-5 (May 2019)
PermalinkGet it right, make it easy, see it all: Viewpoints of autistic individuals and parents of autistic individuals about the autism diagnostic process in Australia / Emily D’ARCY in Research in Autism Spectrum Disorders, 85 (July 2021)
PermalinkIncreased facial asymmetry in autism spectrum conditions is associated with symptom presentation / Maryam BOUTRUS in Autism Research, 12-12 (December)
PermalinkInner speech impairments in autism / Andrew J. O. WHITEHOUSE in Journal of Child Psychology and Psychiatry, 47-8 (August 2006)
PermalinkInvestigating associations between birth order and autism diagnostic phenotypes / Gail A. ALVARES in Journal of Child Psychology and Psychiatry, 62-8 (August 2021)
PermalinkInvestigating facial phenotype in autism spectrum conditions: The importance of a hypothesis driven approach / Maryam BOUTRUS in Autism Research, 10-12 (December 2017)
PermalinkMaternal pre-pregnancy weight and autistic-like traits among offspring in the general population / Kandice J. VARCIN in Autism Research, 12-1 (January 2019)
PermalinkMaternal Vitamin D Levels and the Autism Phenotype Among Offspring / Andrew J. O. WHITEHOUSE in Journal of Autism and Developmental Disorders, 43-7 (July 2013)
PermalinkMothers of Children with Autism have Different Rates of Cancer According to the Presence of Intellectual Disability in Their Child / Jennifer C. FAIRTHORNE in Journal of Autism and Developmental Disorders, 46-9 (September 2016)
PermalinkNarrowing the broader autism phenotype: A study using the Communication Checklist - Adult Version (CC-A) / Andrew J. O. WHITEHOUSE in Autism, 14-6 (November 2010)
PermalinkNon-pharmacological interventions for autistic children: An umbrella review / David TREMBATH in Autism, 27-2 (February 2023)
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