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Injuries in Children with Autism Spectrum Disorder: Study to Explore Early Development (SEED) / Carolyn G. DIGUISEPPI in Journal of Autism and Developmental Disorders, 48-2 (February 2018)
[article]
Titre : Injuries in Children with Autism Spectrum Disorder: Study to Explore Early Development (SEED) Type de document : Texte imprimé et/ou numérique Auteurs : Carolyn G. DIGUISEPPI, Auteur ; S. E. LEVY, Auteur ; Katherine R. SABOURIN, Auteur ; G. N. SOKE, Auteur ; S. ROSENBERG, Auteur ; L. C. LEE, Auteur ; E. MOODY, Auteur ; Laura A. SCHIEVE, Auteur Article en page(s) : p.461-472 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Developmental delays and disorders Epidemiology Injuries Prevalence Index. décimale : PER Périodiques Résumé : This study examined caregiver-reported medically-attended injuries among 30-68 month old children with autism spectrum disorder (ASD) compared to general population (POP) and non-ASD developmental disorders (DD) controls in the Study to Explore Early Development. Injuries were common in ASD cases (32.3%) as well as POP (30.2%) and DD (27.8%) controls; most resulted in an emergency visit or hospitalization. After accounting for sociodemographic, health, IQ and behavior differences, odds of injury in ASD cases were significantly higher than DD controls but similar to POP controls. Attention problems mediated the relationships. Clinicians caring for children with both ASD and attention problems should consider providing targeted safety advice. Differences in injury risk between children with ASD vs. other developmental disorders need further study. En ligne : https://doi.org/10.1007/s10803-017-3337-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=337
in Journal of Autism and Developmental Disorders > 48-2 (February 2018) . - p.461-472[article] Injuries in Children with Autism Spectrum Disorder: Study to Explore Early Development (SEED) [Texte imprimé et/ou numérique] / Carolyn G. DIGUISEPPI, Auteur ; S. E. LEVY, Auteur ; Katherine R. SABOURIN, Auteur ; G. N. SOKE, Auteur ; S. ROSENBERG, Auteur ; L. C. LEE, Auteur ; E. MOODY, Auteur ; Laura A. SCHIEVE, Auteur . - p.461-472.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 48-2 (February 2018) . - p.461-472
Mots-clés : Autism spectrum disorder Developmental delays and disorders Epidemiology Injuries Prevalence Index. décimale : PER Périodiques Résumé : This study examined caregiver-reported medically-attended injuries among 30-68 month old children with autism spectrum disorder (ASD) compared to general population (POP) and non-ASD developmental disorders (DD) controls in the Study to Explore Early Development. Injuries were common in ASD cases (32.3%) as well as POP (30.2%) and DD (27.8%) controls; most resulted in an emergency visit or hospitalization. After accounting for sociodemographic, health, IQ and behavior differences, odds of injury in ASD cases were significantly higher than DD controls but similar to POP controls. Attention problems mediated the relationships. Clinicians caring for children with both ASD and attention problems should consider providing targeted safety advice. Differences in injury risk between children with ASD vs. other developmental disorders need further study. En ligne : https://doi.org/10.1007/s10803-017-3337-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=337 Use of medication for attention-deficit/hyperactivity disorder and risk of unintentional injuries in children and adolescents with co-occurring neurodevelopmental disorders / Laura GHIRARDI in Journal of Child Psychology and Psychiatry, 61-2 (February 2020)
[article]
Titre : Use of medication for attention-deficit/hyperactivity disorder and risk of unintentional injuries in children and adolescents with co-occurring neurodevelopmental disorders Type de document : Texte imprimé et/ou numérique Auteurs : Laura GHIRARDI, Auteur ; Qi CHEN, Auteur ; Zheng CHANG, Auteur ; Ralf KUJA-HALKOLA, Auteur ; Charlotte SKOGLUND, Auteur ; Patrick D. QUINN, Auteur ; Brian M. D'ONOFRIO, Auteur ; Henrik LARSSON, Auteur Article en page(s) : p.140-147 Langues : Anglais (eng) Mots-clés : ADHD medication injuries neurodevelopmental disorders Index. décimale : PER Périodiques Résumé : BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is often associated with other neurodevelopmental disorders (NDs) and with risky behaviors and adverse health outcomes, including injuries. Treatment with ADHD medication has been associated with reduced risk of injuries. However, it is unknown whether the association is present in individuals with co-occurring NDs. The aim of the present study was to estimate the association between ADHD medication use and unintentional injuries in Sweden in children and adolescents with ADHD, including those with co-occurring NDs. METHODS: Using a linkage of several national registers via the unique personal identification number, we identified individuals with a diagnosis of ADHD and of other NDs, including autism spectrum disorder, intellectual disability, communication disorders, learning disorders and motor disorders. The primary outcome was unintentional injuries. Secondary outcome was traumatic brain injury (TBI). Individuals were followed from January 1st 2006 or their 5th birthday or the date of the first unintentional injury, whichever came last, to December 31st 2013 or their 18th birthday or death, whichever came first. We compared the rate of injuries during periods on-treatment with the rate of injuries during periods off-treatment within the same individual using stratified Cox regression to calculate hazard ratio (HR) with 95% confidence intervals (CIs). RESULTS: For children and adolescents with ADHD (N = 9,421) the rate of any unintentional injuries (HR = 0.85; 95% CI = 0.78-0.92) and TBIs (HR = 0.27; 95% CIs = 0.20-0.38) during medicated periods was lower than during non-medicated periods. Similar results were found among individuals with co-occurring NDs (N = 2,986), for unintentional injuries (HR = 0.88; 95% CI = 0.77-1.01) and for TBIs (HR = 0.27; 95% CI = 0.16-0.44). CONCLUSIONS: Beneficial effects of ADHD medication may extend beyond reduction of ADHD core symptoms to prevention of unintentional injuries in children and adolescents, including individuals with co-occurring NDs. En ligne : http://dx.doi.org/10.1111/jcpp.13136 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=415
in Journal of Child Psychology and Psychiatry > 61-2 (February 2020) . - p.140-147[article] Use of medication for attention-deficit/hyperactivity disorder and risk of unintentional injuries in children and adolescents with co-occurring neurodevelopmental disorders [Texte imprimé et/ou numérique] / Laura GHIRARDI, Auteur ; Qi CHEN, Auteur ; Zheng CHANG, Auteur ; Ralf KUJA-HALKOLA, Auteur ; Charlotte SKOGLUND, Auteur ; Patrick D. QUINN, Auteur ; Brian M. D'ONOFRIO, Auteur ; Henrik LARSSON, Auteur . - p.140-147.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-2 (February 2020) . - p.140-147
Mots-clés : ADHD medication injuries neurodevelopmental disorders Index. décimale : PER Périodiques Résumé : BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is often associated with other neurodevelopmental disorders (NDs) and with risky behaviors and adverse health outcomes, including injuries. Treatment with ADHD medication has been associated with reduced risk of injuries. However, it is unknown whether the association is present in individuals with co-occurring NDs. The aim of the present study was to estimate the association between ADHD medication use and unintentional injuries in Sweden in children and adolescents with ADHD, including those with co-occurring NDs. METHODS: Using a linkage of several national registers via the unique personal identification number, we identified individuals with a diagnosis of ADHD and of other NDs, including autism spectrum disorder, intellectual disability, communication disorders, learning disorders and motor disorders. The primary outcome was unintentional injuries. Secondary outcome was traumatic brain injury (TBI). Individuals were followed from January 1st 2006 or their 5th birthday or the date of the first unintentional injury, whichever came last, to December 31st 2013 or their 18th birthday or death, whichever came first. We compared the rate of injuries during periods on-treatment with the rate of injuries during periods off-treatment within the same individual using stratified Cox regression to calculate hazard ratio (HR) with 95% confidence intervals (CIs). RESULTS: For children and adolescents with ADHD (N = 9,421) the rate of any unintentional injuries (HR = 0.85; 95% CI = 0.78-0.92) and TBIs (HR = 0.27; 95% CIs = 0.20-0.38) during medicated periods was lower than during non-medicated periods. Similar results were found among individuals with co-occurring NDs (N = 2,986), for unintentional injuries (HR = 0.88; 95% CI = 0.77-1.01) and for TBIs (HR = 0.27; 95% CI = 0.16-0.44). CONCLUSIONS: Beneficial effects of ADHD medication may extend beyond reduction of ADHD core symptoms to prevention of unintentional injuries in children and adolescents, including individuals with co-occurring NDs. En ligne : http://dx.doi.org/10.1111/jcpp.13136 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=415 Injury-related treatments and outcomes in preschool children with autism spectrum disorder: Study to Explore Early Development (SEED) / Carolyn G. DIGUISEPPI in Research in Autism Spectrum Disorders, 66 (October 2019)
[article]
Titre : Injury-related treatments and outcomes in preschool children with autism spectrum disorder: Study to Explore Early Development (SEED) Type de document : Texte imprimé et/ou numérique Auteurs : Carolyn G. DIGUISEPPI, Auteur ; Katherine R. SABOURIN, Auteur ; Susan E. LEVY, Auteur ; Gnakub N. SOKE, Auteur ; Li-Ching LEE, Auteur ; Lisa D. WIGGINS, Auteur ; Laura A. SCHIEVE, Auteur Article en page(s) : p.101413 Langues : Anglais (eng) Mots-clés : ASD Injuries Surgery Emergency care Injury outcomes Treatment Index. décimale : PER Périodiques Résumé : Background Evidence about injury management and outcomes in children with autism spectrum disorder (ASD) is limited. Method Cross-sectional analyses included children aged 30–68 months with at least one medically attended injury. Standardized diagnostic instruments determined ASD cases. Parent-reported injury treatments and outcomes were examined in ASD cases (n?=?224) versus developmental delays/disorders (DD) (n?=?188) and population (POP) (n?=?267) controls, adjusting for child and family characteristics using logistic regression. Results Injury characteristics were similar between groups. Most children (82.5%) had emergency care (EC) or hospitalization after injury. Nearly half (46.4%) ever received a medication or injection, mostly analgesics (53.4%) and local anesthetics (23.8%), while 9.4% ever received surgery, most often for open wound (47.0%) or fracture (16.7%). ASD group children were less likely than DD group children to receive medication/injection (41.1% vs. 53.2%, adjusted odds ratio [aOR]?=?0.60 [0.40, 0.90]); receipt of EC/hospitalization and surgery were comparable. Children with ASD more often had surgery than POP children (14.3% vs. 4.9%, aOR?=?2.62 [1.31, 5.25]); receipt of EC/hospitalization and medication/injection were similar. Loss of consciousness was uncommon (ASD?=?6.3%, DD?=?5.3%, POP?=?3.4%), as was long-term or significant behavior change (ASD?=?5.4%, DD?=?3.2%, POP?=?3.2%); differences were not significant. Conclusions Injured children with ASD received fewer medications/injections than children with non-ASD developmental delays/disorders and more surgical treatments than general population children. Injury management was otherwise similar between groups. Understanding whether these results reflect child or injury characteristics or provider perceptions about behaviors and pain thresholds of children with ASD, and how these may influence care, requires further study. En ligne : https://doi.org/10.1016/j.rasd.2019.101413 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=404
in Research in Autism Spectrum Disorders > 66 (October 2019) . - p.101413[article] Injury-related treatments and outcomes in preschool children with autism spectrum disorder: Study to Explore Early Development (SEED) [Texte imprimé et/ou numérique] / Carolyn G. DIGUISEPPI, Auteur ; Katherine R. SABOURIN, Auteur ; Susan E. LEVY, Auteur ; Gnakub N. SOKE, Auteur ; Li-Ching LEE, Auteur ; Lisa D. WIGGINS, Auteur ; Laura A. SCHIEVE, Auteur . - p.101413.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 66 (October 2019) . - p.101413
Mots-clés : ASD Injuries Surgery Emergency care Injury outcomes Treatment Index. décimale : PER Périodiques Résumé : Background Evidence about injury management and outcomes in children with autism spectrum disorder (ASD) is limited. Method Cross-sectional analyses included children aged 30–68 months with at least one medically attended injury. Standardized diagnostic instruments determined ASD cases. Parent-reported injury treatments and outcomes were examined in ASD cases (n?=?224) versus developmental delays/disorders (DD) (n?=?188) and population (POP) (n?=?267) controls, adjusting for child and family characteristics using logistic regression. Results Injury characteristics were similar between groups. Most children (82.5%) had emergency care (EC) or hospitalization after injury. Nearly half (46.4%) ever received a medication or injection, mostly analgesics (53.4%) and local anesthetics (23.8%), while 9.4% ever received surgery, most often for open wound (47.0%) or fracture (16.7%). ASD group children were less likely than DD group children to receive medication/injection (41.1% vs. 53.2%, adjusted odds ratio [aOR]?=?0.60 [0.40, 0.90]); receipt of EC/hospitalization and surgery were comparable. Children with ASD more often had surgery than POP children (14.3% vs. 4.9%, aOR?=?2.62 [1.31, 5.25]); receipt of EC/hospitalization and medication/injection were similar. Loss of consciousness was uncommon (ASD?=?6.3%, DD?=?5.3%, POP?=?3.4%), as was long-term or significant behavior change (ASD?=?5.4%, DD?=?3.2%, POP?=?3.2%); differences were not significant. Conclusions Injured children with ASD received fewer medications/injections than children with non-ASD developmental delays/disorders and more surgical treatments than general population children. Injury management was otherwise similar between groups. Understanding whether these results reflect child or injury characteristics or provider perceptions about behaviors and pain thresholds of children with ASD, and how these may influence care, requires further study. En ligne : https://doi.org/10.1016/j.rasd.2019.101413 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=404