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Autism screening at 18 months of age: a comparison of the Q-CHAT-10 and M-CHAT screeners / R. STURNER in Molecular Autism, 13 (2022)
[article]
Titre : Autism screening at 18 months of age: a comparison of the Q-CHAT-10 and M-CHAT screeners Type de document : Texte imprimé et/ou numérique Auteurs : R. STURNER, Auteur ; B. HOWARD, Auteur ; P. BERGMANN, Auteur ; S. ATTAR, Auteur ; L. STEWART-ARTZ, Auteur ; K. BET, Auteur ; Carrie ALLISON, Auteur ; Simon BARON-COHEN, Auteur Article en page(s) : 2p. Langues : Anglais (eng) Mots-clés : Autism screening Developmental screening M-chat Q-CHAT Primary Care and its for-profit subsidiary, CHADIS, Inc. CHADIS, the web-tool used in the study was developed by Dr. Sturner and his spouse, Dr. Howard. Dr. Sturner is Director of the Center and Dr. Howard is President of CHADIS, Inc. Both are members of the Board of Directors of Center and are paid employees or consultants to both entities. The other authors have indicated they have no financial relationships relevant to this article to disclose. Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism screening is recommended at 18- and 24-month pediatric well visits. The Modified Checklist for Autism in Toddlers-Revised (M-CHAT-R) authors recommend a follow-up interview (M-CHAT-R/F) when positive. M-CHAT-R/F may be less accurate for 18-month-olds than 24-month-olds and accuracy for identification prior to two years is not known in samples that include children screening negative. Since autism symptoms may emerge gradually, ordinally scoring items based on the full range of response options, such as in the 10-item version of the Quantitative Checklist for Autism in Toddlers (Q-CHAT-10), might better capture autism signs than the dichotomous (i.e., yes/no) items in M-CHAT-R or the pass/fail scoring of Q-CHAT-10 items. The aims of this study were to determine and compare the accuracy of the M-CHAT-R/F and the Q-CHAT-10 and to describe the accuracy of the ordinally scored Q-CHAT-10 (Q-CHAT-10-O) for predicting autism in a sample of children who were screened at 18 months. METHODS: This is a community pediatrics validation study with screen positive (n?=?167) and age- and practice-matched screen negative children (n?=?241) recruited for diagnostic evaluations completed prior to 2 years old. Clinical diagnosis of autism was based on results of in-person diagnostic autism evaluations by research reliable testers blind to screening results and using the Autism Diagnostic Observation Schedule-Second Edition (ADOS-2) Toddler Module and Mullen Scales of Early Learning (MSEL) per standard guidelines. RESULTS: While the M-CHAT-R/F had higher specificity and PPV compared to M-CHAT-R, Q-CHAT-10-O showed higher sensitivity than M-CHAT-R/F and Q-CHAT-10. LIMITATIONS: Many parents declined participation and the sample is over-represented by higher educated parents. Results cannot be extended to older ages. CONCLUSIONS: Limitations of the currently recommended two-stage M-CHAT-R/F at the 18-month visit include low sensitivity with minimal balancing benefit of improved PPV from the follow-up interview. Ordinal, rather than dichotomous, scoring of autism screening items appears to be beneficial at this age. The Q-CHAT-10-O with ordinal scoring shows advantages to M-CHAT-R/F with half the number of items, no requirement for a follow-up interview, and improved sensitivity. Yet, Q-CHAT-10-O sensitivity is less than M-CHAT-R (without follow-up) and specificity is less than the two-stage procedure. Such limitations are consistent with recognition that screening needs to recur beyond this age. En ligne : http://dx.doi.org/10.1186/s13229-021-00480-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459
in Molecular Autism > 13 (2022) . - 2p.[article] Autism screening at 18 months of age: a comparison of the Q-CHAT-10 and M-CHAT screeners [Texte imprimé et/ou numérique] / R. STURNER, Auteur ; B. HOWARD, Auteur ; P. BERGMANN, Auteur ; S. ATTAR, Auteur ; L. STEWART-ARTZ, Auteur ; K. BET, Auteur ; Carrie ALLISON, Auteur ; Simon BARON-COHEN, Auteur . - 2p.
Langues : Anglais (eng)
in Molecular Autism > 13 (2022) . - 2p.
Mots-clés : Autism screening Developmental screening M-chat Q-CHAT Primary Care and its for-profit subsidiary, CHADIS, Inc. CHADIS, the web-tool used in the study was developed by Dr. Sturner and his spouse, Dr. Howard. Dr. Sturner is Director of the Center and Dr. Howard is President of CHADIS, Inc. Both are members of the Board of Directors of Center and are paid employees or consultants to both entities. The other authors have indicated they have no financial relationships relevant to this article to disclose. Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism screening is recommended at 18- and 24-month pediatric well visits. The Modified Checklist for Autism in Toddlers-Revised (M-CHAT-R) authors recommend a follow-up interview (M-CHAT-R/F) when positive. M-CHAT-R/F may be less accurate for 18-month-olds than 24-month-olds and accuracy for identification prior to two years is not known in samples that include children screening negative. Since autism symptoms may emerge gradually, ordinally scoring items based on the full range of response options, such as in the 10-item version of the Quantitative Checklist for Autism in Toddlers (Q-CHAT-10), might better capture autism signs than the dichotomous (i.e., yes/no) items in M-CHAT-R or the pass/fail scoring of Q-CHAT-10 items. The aims of this study were to determine and compare the accuracy of the M-CHAT-R/F and the Q-CHAT-10 and to describe the accuracy of the ordinally scored Q-CHAT-10 (Q-CHAT-10-O) for predicting autism in a sample of children who were screened at 18 months. METHODS: This is a community pediatrics validation study with screen positive (n?=?167) and age- and practice-matched screen negative children (n?=?241) recruited for diagnostic evaluations completed prior to 2 years old. Clinical diagnosis of autism was based on results of in-person diagnostic autism evaluations by research reliable testers blind to screening results and using the Autism Diagnostic Observation Schedule-Second Edition (ADOS-2) Toddler Module and Mullen Scales of Early Learning (MSEL) per standard guidelines. RESULTS: While the M-CHAT-R/F had higher specificity and PPV compared to M-CHAT-R, Q-CHAT-10-O showed higher sensitivity than M-CHAT-R/F and Q-CHAT-10. LIMITATIONS: Many parents declined participation and the sample is over-represented by higher educated parents. Results cannot be extended to older ages. CONCLUSIONS: Limitations of the currently recommended two-stage M-CHAT-R/F at the 18-month visit include low sensitivity with minimal balancing benefit of improved PPV from the follow-up interview. Ordinal, rather than dichotomous, scoring of autism screening items appears to be beneficial at this age. The Q-CHAT-10-O with ordinal scoring shows advantages to M-CHAT-R/F with half the number of items, no requirement for a follow-up interview, and improved sensitivity. Yet, Q-CHAT-10-O sensitivity is less than M-CHAT-R (without follow-up) and specificity is less than the two-stage procedure. Such limitations are consistent with recognition that screening needs to recur beyond this age. En ligne : http://dx.doi.org/10.1186/s13229-021-00480-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459 Concurrent Validity of the Modified Checklist for Autism in Toddlers (M-CHAT): Socio-cognitive and Verbal Skills in 18-Month-Old Infants / Alexa RUEL in Journal of Autism and Developmental Disorders, 51-3 (March 2021)
[article]
Titre : Concurrent Validity of the Modified Checklist for Autism in Toddlers (M-CHAT): Socio-cognitive and Verbal Skills in 18-Month-Old Infants Type de document : Texte imprimé et/ou numérique Auteurs : Alexa RUEL, Auteur ; Sabrina S. CHIARELLA, Auteur ; Cristina CRIVELLO, Auteur ; Diane POULIN-DUBOIS, Auteur Article en page(s) : p.933-949 Langues : Anglais (eng) Mots-clés : Concurrent validity Infants M-chat Socio-cognitive abilities Word learning Index. décimale : PER Périodiques Résumé : The Modified Checklist for Autism in Toddlers (M-CHAT) is a screening questionnaire for Autism Spectrum Disorder (ASD). Previous findings have confirmed the M-CHAT's sensitivity and specificity across several cultures, yet few studies have considered M-CHAT scores as a distributed trait in a sample of typical infants. The current study examined how the M-CHAT predicts concurrent word learning (experiment 1) as well as socio-emotional understanding (experiment 2) in 18-month-old infants. Results demonstrated that the number of items endorsed on the M-CHAT negatively correlated with the proportion of trials on which infants looked at a toy named by the experimenter as well as performance on the word learning task. In experiment 2, high scores on the M-CHAT correlated with less instrumental helping, less imitation, and a smaller productive vocabulary size. En ligne : http://dx.doi.org/10.1007/s10803-020-04379-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=443
in Journal of Autism and Developmental Disorders > 51-3 (March 2021) . - p.933-949[article] Concurrent Validity of the Modified Checklist for Autism in Toddlers (M-CHAT): Socio-cognitive and Verbal Skills in 18-Month-Old Infants [Texte imprimé et/ou numérique] / Alexa RUEL, Auteur ; Sabrina S. CHIARELLA, Auteur ; Cristina CRIVELLO, Auteur ; Diane POULIN-DUBOIS, Auteur . - p.933-949.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 51-3 (March 2021) . - p.933-949
Mots-clés : Concurrent validity Infants M-chat Socio-cognitive abilities Word learning Index. décimale : PER Périodiques Résumé : The Modified Checklist for Autism in Toddlers (M-CHAT) is a screening questionnaire for Autism Spectrum Disorder (ASD). Previous findings have confirmed the M-CHAT's sensitivity and specificity across several cultures, yet few studies have considered M-CHAT scores as a distributed trait in a sample of typical infants. The current study examined how the M-CHAT predicts concurrent word learning (experiment 1) as well as socio-emotional understanding (experiment 2) in 18-month-old infants. Results demonstrated that the number of items endorsed on the M-CHAT negatively correlated with the proportion of trials on which infants looked at a toy named by the experimenter as well as performance on the word learning task. In experiment 2, high scores on the M-CHAT correlated with less instrumental helping, less imitation, and a smaller productive vocabulary size. En ligne : http://dx.doi.org/10.1007/s10803-020-04379-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=443 Examination of the Properties of the Modified Checklist for Autism in Toddlers (M-CHAT) in a Population Sample / Brie YAMA in Journal of Autism and Developmental Disorders, 42-1 (January 2012)
[article]
Titre : Examination of the Properties of the Modified Checklist for Autism in Toddlers (M-CHAT) in a Population Sample Type de document : Texte imprimé et/ou numérique Auteurs : Brie YAMA, Auteur ; Tom FREEMAN, Auteur ; Erin GRAVES, Auteur ; Su YUAN, Auteur ; M. KAREN CAMPBELL, Auteur Année de publication : 2012 Article en page(s) : p.23-34 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders Autism Modified checklist for autism in toddlers M-CHAT Toddlers Developmental screening Index. décimale : PER Périodiques Résumé : This study examines the following properties of the Modified Checklist for Autism in Toddlers (M-CHAT) in an unselected low-risk sample: (a) the maximum age for screen administration; (b) the positive screen rate in the absence of follow-up telephone interviews and; (c) the distributional properties of positive screens. Data came from a prospective cohort study (n = 1,604). Results suggest that the M-CHAT can appropriately be administered to children aged 20–48 months. Documented explanations provided by mothers during screening, appear to effectively identify potential screen misclassifications in the absence of the follow-up telephone interviews. This further emphasizes the importance of clinician expertise in verifying positive M-CHAT screens. Results have implications for the administration of the M-CHAT in clinical and research settings. En ligne : http://dx.doi.org/10.1007/s10803-011-1211-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=151
in Journal of Autism and Developmental Disorders > 42-1 (January 2012) . - p.23-34[article] Examination of the Properties of the Modified Checklist for Autism in Toddlers (M-CHAT) in a Population Sample [Texte imprimé et/ou numérique] / Brie YAMA, Auteur ; Tom FREEMAN, Auteur ; Erin GRAVES, Auteur ; Su YUAN, Auteur ; M. KAREN CAMPBELL, Auteur . - 2012 . - p.23-34.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-1 (January 2012) . - p.23-34
Mots-clés : Autism spectrum disorders Autism Modified checklist for autism in toddlers M-CHAT Toddlers Developmental screening Index. décimale : PER Périodiques Résumé : This study examines the following properties of the Modified Checklist for Autism in Toddlers (M-CHAT) in an unselected low-risk sample: (a) the maximum age for screen administration; (b) the positive screen rate in the absence of follow-up telephone interviews and; (c) the distributional properties of positive screens. Data came from a prospective cohort study (n = 1,604). Results suggest that the M-CHAT can appropriately be administered to children aged 20–48 months. Documented explanations provided by mothers during screening, appear to effectively identify potential screen misclassifications in the absence of the follow-up telephone interviews. This further emphasizes the importance of clinician expertise in verifying positive M-CHAT screens. Results have implications for the administration of the M-CHAT in clinical and research settings. En ligne : http://dx.doi.org/10.1007/s10803-011-1211-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=151 Modified Checklist for Autism in Toddlers (M-CHAT) screening at 18 months of age predicts concurrent understanding of desires, word learning and expressive vocabulary / Kristyn WRIGHT in Research in Autism Spectrum Disorders, 6-1 (January-March 2012)
[article]
Titre : Modified Checklist for Autism in Toddlers (M-CHAT) screening at 18 months of age predicts concurrent understanding of desires, word learning and expressive vocabulary Type de document : Texte imprimé et/ou numérique Auteurs : Kristyn WRIGHT, Auteur ; Diane POULIN-DUBOIS, Auteur Année de publication : 2012 Article en page(s) : p.184-192 Langues : Anglais (eng) Mots-clés : Autism M-CHAT Developmental screening Theory of mind Expressive language Index. décimale : PER Périodiques Résumé : The Modified Checklist for Autism in Toddlers (M-CHAT) is a 23-item questionnaire used in primary screening of Autism Spectrum Disorder (ASD). The current studies examine the concurrent validity of the M-CHAT in its ability to predict 18-month-olds’ performance on theory of mind and word learning tasks. In Experiment 1, infants’ understanding of desires was tested using a modified food request task. Experiment 2 assessed infants’ ability to learn novel words. Results indicate that infants’ score on the M-CHAT significantly predicts their performance on both the desire understanding and the novel word learning task. As expected, the number of items endorsed on the M-CHAT also relates to infants’ expressive vocabulary at 18 months of age. Taken together, these findings confirm the concurrent validity of the M-CHAT at the youngest age this measure can reliably be administered. Within a broader clinical context, the present results provide preliminary evidence that controlled laboratory tasks assessing early social cognitive and verbal abilities could be added to the battery of screening instruments for ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2011.04.004 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=146
in Research in Autism Spectrum Disorders > 6-1 (January-March 2012) . - p.184-192[article] Modified Checklist for Autism in Toddlers (M-CHAT) screening at 18 months of age predicts concurrent understanding of desires, word learning and expressive vocabulary [Texte imprimé et/ou numérique] / Kristyn WRIGHT, Auteur ; Diane POULIN-DUBOIS, Auteur . - 2012 . - p.184-192.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 6-1 (January-March 2012) . - p.184-192
Mots-clés : Autism M-CHAT Developmental screening Theory of mind Expressive language Index. décimale : PER Périodiques Résumé : The Modified Checklist for Autism in Toddlers (M-CHAT) is a 23-item questionnaire used in primary screening of Autism Spectrum Disorder (ASD). The current studies examine the concurrent validity of the M-CHAT in its ability to predict 18-month-olds’ performance on theory of mind and word learning tasks. In Experiment 1, infants’ understanding of desires was tested using a modified food request task. Experiment 2 assessed infants’ ability to learn novel words. Results indicate that infants’ score on the M-CHAT significantly predicts their performance on both the desire understanding and the novel word learning task. As expected, the number of items endorsed on the M-CHAT also relates to infants’ expressive vocabulary at 18 months of age. Taken together, these findings confirm the concurrent validity of the M-CHAT at the youngest age this measure can reliably be administered. Within a broader clinical context, the present results provide preliminary evidence that controlled laboratory tasks assessing early social cognitive and verbal abilities could be added to the battery of screening instruments for ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2011.04.004 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=146 Parent-Endorsed Sex Differences in Toddlers with and Without ASD: Utilizing the M-CHAT / Roald A. ØIEN in Journal of Autism and Developmental Disorders, 47-1 (January 2017)
[article]
Titre : Parent-Endorsed Sex Differences in Toddlers with and Without ASD: Utilizing the M-CHAT Type de document : Texte imprimé et/ou numérique Auteurs : Roald A. ØIEN, Auteur ; Logan HART, Auteur ; Synnve SCHJØLBERG, Auteur ; Carla A. WALL, Auteur ; Elizabeth S. KIM, Auteur ; Anders NORDAHL-HANSEN, Auteur ; Martin R. EISEMANN, Auteur ; Katarzyna CHAWARSKA, Auteur ; Fred R. VOLKMAR, Auteur ; Frederick SHIC, Auteur Article en page(s) : p.126-134 Langues : Anglais (eng) Mots-clés : Sex differences Gender differences Behavior Autistic traits m-Chat Identification Index. décimale : PER Périodiques Résumé : Sex differences in typical development can provide context for understanding ASD. Baron-Cohen (Trends Cogn Sci 6(6):248–254, 2002) suggested ASD could be considered an extreme expression of normal male, compared to female, phenotypic profiles. In this paper, sex-specific M-CHAT scores from N?=?53,728 18-month-old toddlers, including n?=?185 (32 females) with ASD, were examined. Results suggest a nuanced view of the “extreme male brain theory of autism”. At an item level, almost every male versus female disadvantage in the broader population was consistent with M-CHAT vulnerabilities in ASD. However, controlling for total M-CHAT failures, this male disadvantage was more equivocal and many classically ASD-associated features were found more common in non-ASD. Within ASD, females showed relative strengths in joint attention, but impairments in imitation. En ligne : http://dx.doi.org/10.1007/s10803-016-2945-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298
in Journal of Autism and Developmental Disorders > 47-1 (January 2017) . - p.126-134[article] Parent-Endorsed Sex Differences in Toddlers with and Without ASD: Utilizing the M-CHAT [Texte imprimé et/ou numérique] / Roald A. ØIEN, Auteur ; Logan HART, Auteur ; Synnve SCHJØLBERG, Auteur ; Carla A. WALL, Auteur ; Elizabeth S. KIM, Auteur ; Anders NORDAHL-HANSEN, Auteur ; Martin R. EISEMANN, Auteur ; Katarzyna CHAWARSKA, Auteur ; Fred R. VOLKMAR, Auteur ; Frederick SHIC, Auteur . - p.126-134.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-1 (January 2017) . - p.126-134
Mots-clés : Sex differences Gender differences Behavior Autistic traits m-Chat Identification Index. décimale : PER Périodiques Résumé : Sex differences in typical development can provide context for understanding ASD. Baron-Cohen (Trends Cogn Sci 6(6):248–254, 2002) suggested ASD could be considered an extreme expression of normal male, compared to female, phenotypic profiles. In this paper, sex-specific M-CHAT scores from N?=?53,728 18-month-old toddlers, including n?=?185 (32 females) with ASD, were examined. Results suggest a nuanced view of the “extreme male brain theory of autism”. At an item level, almost every male versus female disadvantage in the broader population was consistent with M-CHAT vulnerabilities in ASD. However, controlling for total M-CHAT failures, this male disadvantage was more equivocal and many classically ASD-associated features were found more common in non-ASD. Within ASD, females showed relative strengths in joint attention, but impairments in imitation. En ligne : http://dx.doi.org/10.1007/s10803-016-2945-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 True versus false positives and negatives on the Modified Checklist For Autism in Toddlers / Johnny L. MATSON in Research in Autism Spectrum Disorders, 7-1 (January 2013)
PermalinkScreening accuracy for risk of autism spectrum disorder using the Brief Infant-Toddler Social and Emotional Assessment (BITSEA) / Lauren M. GARDNER in Research in Autism Spectrum Disorders, 7-5 (May 2013)
PermalinkAccurate Autism Screening at the 18-Month Well-Child Visit Requires Different Strategies than at 24 Months / Raymond STURNER in Journal of Autism and Developmental Disorders, 47-10 (October 2017)
PermalinkAutism and Developmental Screening in a Public, Primary Care Setting Primarily Serving Hispanics: Challenges and Results / Gayle C. WINDHAM in Journal of Autism and Developmental Disorders, 44-7 (July 2014)
PermalinkAutism-risk screening in the first 3 years of life in Taiwan Birth Cohort Pilot Study / For-Wey LUNG in Research in Autism Spectrum Disorders, 5-4 (October-December 2011)
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