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Early Signs of Autism in Toddlers: A Follow-Up Study in the Danish National Birth Cohort / Sanne LEMCKE in Journal of Autism and Developmental Disorders, 43-10 (October 2013)
[article]
Titre : Early Signs of Autism in Toddlers: A Follow-Up Study in the Danish National Birth Cohort Type de document : Texte imprimé et/ou numérique Auteurs : Sanne LEMCKE, Auteur ; Svend JUUL, Auteur ; Erik T. PARNER, Auteur ; Marlene B. LAURITSEN, Auteur ; Poul THORSEN, Auteur Article en page(s) : p.2366-2375 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Intellectual disability Early signs Parents’ interview Follow-up study Birth cohort Index. décimale : PER Périodiques Résumé : To identify possible early signs of autism spectrum disorder (ASD) within the Danish National Birth Cohort, we studied prospectively collected interviews from 76,441 mothers about their children’s development and behaviour at 6 and 18 months. In Danish national registries, 720 children with ASD and 231 children with intellectual disability (ID) were identified. At 6 months, associations between early signs and ASD or ID were found only in few areas. At 18 months social, language, and motor skills were delayed, and suspicion of vision and hearing problems were increased for both groups. Signs distinguishing ASD from ID were unclear, and the positive predictive values regarding ASD were below 10 % for individual predictors and aggregated risk scores. En ligne : http://dx.doi.org/10.1007/s10803-013-1785-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215
in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2366-2375[article] Early Signs of Autism in Toddlers: A Follow-Up Study in the Danish National Birth Cohort [Texte imprimé et/ou numérique] / Sanne LEMCKE, Auteur ; Svend JUUL, Auteur ; Erik T. PARNER, Auteur ; Marlene B. LAURITSEN, Auteur ; Poul THORSEN, Auteur . - p.2366-2375.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2366-2375
Mots-clés : Autism spectrum disorder Intellectual disability Early signs Parents’ interview Follow-up study Birth cohort Index. décimale : PER Périodiques Résumé : To identify possible early signs of autism spectrum disorder (ASD) within the Danish National Birth Cohort, we studied prospectively collected interviews from 76,441 mothers about their children’s development and behaviour at 6 and 18 months. In Danish national registries, 720 children with ASD and 231 children with intellectual disability (ID) were identified. At 6 months, associations between early signs and ASD or ID were found only in few areas. At 18 months social, language, and motor skills were delayed, and suspicion of vision and hearing problems were increased for both groups. Signs distinguishing ASD from ID were unclear, and the positive predictive values regarding ASD were below 10 % for individual predictors and aggregated risk scores. En ligne : http://dx.doi.org/10.1007/s10803-013-1785-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 A 13-year follow-up of Finnish patients with Salla disease / L. E. PAAVOLA in Journal of Neurodevelopmental Disorders, 7-1 (December 2015)
[article]
Titre : A 13-year follow-up of Finnish patients with Salla disease Type de document : Texte imprimé et/ou numérique Auteurs : L. E. PAAVOLA, Auteur ; A. M. REMES, Auteur ; M. J. HARILA, Auteur ; T. T. VARHO, Auteur ; T. T. KORHONEN, Auteur ; K. MAJAMAA, Auteur Article en page(s) : p.20 Langues : Anglais (eng) Mots-clés : Dysmyelination Follow-up study Free sialic acid storage Neurocognitive development Rare diseases Index. décimale : PER Périodiques Résumé : BACKGROUND: Salla disease (SD) is a rare lysosomal storage disorder leading to severe intellectual disability. SD belongs to the Finnish disease heritage, and it is caused by mutations in the SLC17A5 gene. The aim of the study was to investigate the course of neurocognitive features of SD patients in a long-term follow-up. METHODS: Neuropsychological and neurological investigations were carried out on 24 SD patients, aged 16-65 years, 13 years after a similar examination. RESULTS: The survival analysis showed excess mortality among patients with SD after the age of 30 years. The course of the disease was progressive, but follow-up of SD patients revealed that motor skills improved till the age of 20 years, while mental abilities improved in most patients till 40 years of age. Verbal comprehension skills did not diminish during the follow-up, but productive speech deteriorated because of dyspraxia and dysarthria. Motor deficits were marked. Ataxia was prominent in childhood, but it was replaced by athetotic movements during the teens. Spasticity became more obvious with age especially in severely disabled SD patients. CONCLUSIONS: Younger SD patients performed better in almost every task measuring mental abilities that then seem to remain fairly constant till early sixties. Thus, the results indicate better prognosis in cognitive skills than earlier assumed. There is an apparent decline in motor skills after the age of 20 years. The early neurocognitive development predicts the later course of motor and cognitive development. En ligne : http://dx.doi.org/10.1186/s11689-015-9116-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=347
in Journal of Neurodevelopmental Disorders > 7-1 (December 2015) . - p.20[article] A 13-year follow-up of Finnish patients with Salla disease [Texte imprimé et/ou numérique] / L. E. PAAVOLA, Auteur ; A. M. REMES, Auteur ; M. J. HARILA, Auteur ; T. T. VARHO, Auteur ; T. T. KORHONEN, Auteur ; K. MAJAMAA, Auteur . - p.20.
Langues : Anglais (eng)
in Journal of Neurodevelopmental Disorders > 7-1 (December 2015) . - p.20
Mots-clés : Dysmyelination Follow-up study Free sialic acid storage Neurocognitive development Rare diseases Index. décimale : PER Périodiques Résumé : BACKGROUND: Salla disease (SD) is a rare lysosomal storage disorder leading to severe intellectual disability. SD belongs to the Finnish disease heritage, and it is caused by mutations in the SLC17A5 gene. The aim of the study was to investigate the course of neurocognitive features of SD patients in a long-term follow-up. METHODS: Neuropsychological and neurological investigations were carried out on 24 SD patients, aged 16-65 years, 13 years after a similar examination. RESULTS: The survival analysis showed excess mortality among patients with SD after the age of 30 years. The course of the disease was progressive, but follow-up of SD patients revealed that motor skills improved till the age of 20 years, while mental abilities improved in most patients till 40 years of age. Verbal comprehension skills did not diminish during the follow-up, but productive speech deteriorated because of dyspraxia and dysarthria. Motor deficits were marked. Ataxia was prominent in childhood, but it was replaced by athetotic movements during the teens. Spasticity became more obvious with age especially in severely disabled SD patients. CONCLUSIONS: Younger SD patients performed better in almost every task measuring mental abilities that then seem to remain fairly constant till early sixties. Thus, the results indicate better prognosis in cognitive skills than earlier assumed. There is an apparent decline in motor skills after the age of 20 years. The early neurocognitive development predicts the later course of motor and cognitive development. En ligne : http://dx.doi.org/10.1186/s11689-015-9116-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=347 Childhood Facial Recognition Predicts Adolescent Symptom Severity in Autism Spectrum Disorder / Mart L. J. M. EUSSEN in Autism Research, 8-3 (June 2015)
[article]
Titre : Childhood Facial Recognition Predicts Adolescent Symptom Severity in Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Mart L. J. M. EUSSEN, Auteur ; Anneke LOUWERSE, Auteur ; Catherine M. HERBA, Auteur ; Arthur R. VAN GOOL, Auteur ; Fop VERHEIJ, Auteur ; Frank C. VERHULST, Auteur ; Kirstin GREAVES-LORD, Auteur Article en page(s) : p.261-271 Langues : Anglais (eng) Mots-clés : social cognition face perception neuropsychology follow-up study Index. décimale : PER Périodiques Résumé : Limited accuracy and speed in facial recognition (FR) and in the identification of facial emotions (IFE) have been shown in autism spectrum disorders (ASD). This study aimed at evaluating the predictive value of atypicalities in FR and IFE for future symptom severity in children with ASD. Therefore we performed a seven-year follow-up study in 87 children with ASD. FR and IFE were assessed in childhood (T1: age 6–12) using the Amsterdam Neuropsychological Tasks (ANT). Symptom severity was assessed using the Autism Diagnostic Observation Schedule (ADOS) in childhood and again seven years later during adolescence (T2: age 12–19). Multiple regression analyses were performed to investigate whether FR and IFE in childhood predicted ASD symptom severity in adolescence, while controlling for ASD symptom severity in childhood. We found that more accurate FR significantly predicted lower adolescent ASD symptom severity scores (?R2 = .09), even when controlling for childhood ASD symptom severity. IFE was not a significant predictor of ASD symptom severity in adolescence. From these results it can be concluded, that in children with ASD the accuracy of FR in childhood is a relevant predictor of ASD symptom severity in adolescence. Test results on FR in children with ASD may have prognostic value regarding later symptom severity. En ligne : http://dx.doi.org/10.1002/aur.1443 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=261
in Autism Research > 8-3 (June 2015) . - p.261-271[article] Childhood Facial Recognition Predicts Adolescent Symptom Severity in Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Mart L. J. M. EUSSEN, Auteur ; Anneke LOUWERSE, Auteur ; Catherine M. HERBA, Auteur ; Arthur R. VAN GOOL, Auteur ; Fop VERHEIJ, Auteur ; Frank C. VERHULST, Auteur ; Kirstin GREAVES-LORD, Auteur . - p.261-271.
Langues : Anglais (eng)
in Autism Research > 8-3 (June 2015) . - p.261-271
Mots-clés : social cognition face perception neuropsychology follow-up study Index. décimale : PER Périodiques Résumé : Limited accuracy and speed in facial recognition (FR) and in the identification of facial emotions (IFE) have been shown in autism spectrum disorders (ASD). This study aimed at evaluating the predictive value of atypicalities in FR and IFE for future symptom severity in children with ASD. Therefore we performed a seven-year follow-up study in 87 children with ASD. FR and IFE were assessed in childhood (T1: age 6–12) using the Amsterdam Neuropsychological Tasks (ANT). Symptom severity was assessed using the Autism Diagnostic Observation Schedule (ADOS) in childhood and again seven years later during adolescence (T2: age 12–19). Multiple regression analyses were performed to investigate whether FR and IFE in childhood predicted ASD symptom severity in adolescence, while controlling for ASD symptom severity in childhood. We found that more accurate FR significantly predicted lower adolescent ASD symptom severity scores (?R2 = .09), even when controlling for childhood ASD symptom severity. IFE was not a significant predictor of ASD symptom severity in adolescence. From these results it can be concluded, that in children with ASD the accuracy of FR in childhood is a relevant predictor of ASD symptom severity in adolescence. Test results on FR in children with ASD may have prognostic value regarding later symptom severity. En ligne : http://dx.doi.org/10.1002/aur.1443 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=261 Mental health correlates and potential childhood predictors for the wish to be of the opposite sex in young autistic adults / J. C. CHANG in Autism, 26-1 (January 2022)
[article]
Titre : Mental health correlates and potential childhood predictors for the wish to be of the opposite sex in young autistic adults Type de document : Texte imprimé et/ou numérique Auteurs : J. C. CHANG, Auteur ; Meng-Chuan LAI, Auteur ; Y. M. TAI, Auteur ; S. S. GAU, Auteur Article en page(s) : p.146-159 Langues : Anglais (eng) Mots-clés : autism follow-up study gender dysphoria mental health Index. décimale : PER Périodiques Résumé : Autistic people/people with autism spectrum disorder are more likely to experience gender dysphoria. However, the possible longitudinal predictors and underlying mechanisms of this co-occurrence are unclear. To fill this knowledge gap, we assessed 88 people with autism spectrum disorder and 42 typically developing individuals at their average ages of 13.0 (baseline, childhood/adolescence) and 20.2?years old (follow-up, adulthood). At follow-up, their endorsement on the item "I wish I was the opposite sex" was used to evaluate gender dysphoric symptoms. We compared mental health symptoms between adults with and without this item endorsement at the follow-up assessment. We explored parent-reported family and autism characteristics-related predictors in childhood/adolescence to this item endorsement in adulthood. We found that more autistic adults reported the wish to be of the opposite sex than did typically developing individuals. Autistic adults who endorsed this item experienced more mental health challenges, more school bullying and cyberbullying, more suicidal ideation, and worse quality of life. Moreover, parent-reported lower family support and more stereotyped/repetitive behaviors during childhood/adolescence predicted the self-reported wish to be of the opposite sex in adulthood in autistic individuals. More attention and support should be provided to autistic people regarding gender development and related mental health and quality of life impact, especially during the transition period to young adulthood. En ligne : http://dx.doi.org/10.1177/13623613211024098 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451
in Autism > 26-1 (January 2022) . - p.146-159[article] Mental health correlates and potential childhood predictors for the wish to be of the opposite sex in young autistic adults [Texte imprimé et/ou numérique] / J. C. CHANG, Auteur ; Meng-Chuan LAI, Auteur ; Y. M. TAI, Auteur ; S. S. GAU, Auteur . - p.146-159.
Langues : Anglais (eng)
in Autism > 26-1 (January 2022) . - p.146-159
Mots-clés : autism follow-up study gender dysphoria mental health Index. décimale : PER Périodiques Résumé : Autistic people/people with autism spectrum disorder are more likely to experience gender dysphoria. However, the possible longitudinal predictors and underlying mechanisms of this co-occurrence are unclear. To fill this knowledge gap, we assessed 88 people with autism spectrum disorder and 42 typically developing individuals at their average ages of 13.0 (baseline, childhood/adolescence) and 20.2?years old (follow-up, adulthood). At follow-up, their endorsement on the item "I wish I was the opposite sex" was used to evaluate gender dysphoric symptoms. We compared mental health symptoms between adults with and without this item endorsement at the follow-up assessment. We explored parent-reported family and autism characteristics-related predictors in childhood/adolescence to this item endorsement in adulthood. We found that more autistic adults reported the wish to be of the opposite sex than did typically developing individuals. Autistic adults who endorsed this item experienced more mental health challenges, more school bullying and cyberbullying, more suicidal ideation, and worse quality of life. Moreover, parent-reported lower family support and more stereotyped/repetitive behaviors during childhood/adolescence predicted the self-reported wish to be of the opposite sex in adulthood in autistic individuals. More attention and support should be provided to autistic people regarding gender development and related mental health and quality of life impact, especially during the transition period to young adulthood. En ligne : http://dx.doi.org/10.1177/13623613211024098 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451