Dépouillements

Motor and Tactile-Perceptual Skill Differences Between Individuals with High-Functioning Autism and Typically Developing Individuals Ages 5–21 / Sana M. N. ABU-DAHAB in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2241-2248 Titre : Motor and Tactile-Perceptual Skill Differences Between Individuals with High-Functioning Autism and Typically Developing Individuals Ages 5–21 Type de document : Texte imprimé et/ou numérique Auteurs : Sana M. N. ABU-DAHAB, Auteur ; Elizabeth R. SKIDMORE, Auteur ; Margo B. HOLM, Auteur ; Joan C. ROGERS, Auteur ; Nancy J. MINSHEW, Auteur Article en page(s) : p.2241-2248 Langues : Anglais (eng) Mots-clés : Autism  Motor skills  Coordination  Strength  Tactile-perceptual skills  Stereognosis Index. décimale : PER Périodiques Résumé : We examined motor and tactile-perceptual skills in individuals with high-functioning autism (IHFA) and matched typically developing individuals (TDI) ages 5–21 years. Grip strength, motor speed and coordination were impaired in IHFA compared to matched TDI, and the differences between groups varied with age. Although tactile-perceptual skills of IHFA were impaired compared to TDI on several measures, impairments were significant only for stereognosis. Motor and tactile-perceptual skills should be assessed in children with IHFA and intervention should begin early because these skills are essential to school performance. Impairments in coordination and stereognosis suggest a broad though selective under-development of the circuitry for higher order abilities regardless of domain that is important in the search for the underlying disturbances in neurological development. En ligne : http://dx.doi.org/10.1007/s10803-011-1439-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Motor and Tactile-Perceptual Skill Differences Between Individuals with High-Functioning Autism and Typically Developing Individuals Ages 5–21 [Texte imprimé et/ou numérique] / Sana M. N. ABU-DAHAB, Auteur ; Elizabeth R. SKIDMORE, Auteur ; Margo B. HOLM, Auteur ; Joan C. ROGERS, Auteur ; Nancy J. MINSHEW, Auteur . - p.2241-2248. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2241-2248 Mots-clés : Autism  Motor skills  Coordination  Strength  Tactile-perceptual skills  Stereognosis Index. décimale : PER Périodiques Résumé : We examined motor and tactile-perceptual skills in individuals with high-functioning autism (IHFA) and matched typically developing individuals (TDI) ages 5–21 years. Grip strength, motor speed and coordination were impaired in IHFA compared to matched TDI, and the differences between groups varied with age. Although tactile-perceptual skills of IHFA were impaired compared to TDI on several measures, impairments were significant only for stereognosis. Motor and tactile-perceptual skills should be assessed in children with IHFA and intervention should begin early because these skills are essential to school performance. Impairments in coordination and stereognosis suggest a broad though selective under-development of the circuitry for higher order abilities regardless of domain that is important in the search for the underlying disturbances in neurological development. En ligne : http://dx.doi.org/10.1007/s10803-011-1439-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Visualization and Analysis of Eye Movement Data from Children with Typical and Atypical Development / Terje FALCK-YTTER in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2249-2258 Titre : Visualization and Analysis of Eye Movement Data from Children with Typical and Atypical Development Type de document : Texte imprimé et/ou numérique Auteurs : Terje FALCK-YTTER, Auteur ; Claes HOFSTEN, Auteur ; Christopher GILLBERG, Auteur ; Elisabeth FERNELL, Auteur Article en page(s) : p.2249-2258 Langues : Anglais (eng) Mots-clés : Learning  Eye tracking  Scientific visualization  Bottom-up  Knowledge generation  Autism spectrum disorder  Diagnosis  Attention  Social dominance  Social hierarchies  Conflict  Goals Index. décimale : PER Périodiques Résumé : Looking at other children’s interactions provides rich learning opportunities for a small child. How children with autism look at other children is largely unknown. Using eye tracking, we studied gaze performance in children with autism and neurotypical comparison children while they were watching videos of semi-naturalistic social interactions between young children. Using a novel, bottom-up approach we identified event-related measures that distinguished between groups with high accuracy. The observed effects remained in a subset of the total sample matched on IQ, and were replicated across several different stimuli. The described method facilitates the detection of meaningful patterns in complex eye tracking data. Also, the approach significantly improves visualization, which will help investigators understand, illustrate, and generate new hypotheses. En ligne : http://dx.doi.org/10.1007/s10803-013-1776-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Visualization and Analysis of Eye Movement Data from Children with Typical and Atypical Development [Texte imprimé et/ou numérique] / Terje FALCK-YTTER, Auteur ; Claes HOFSTEN, Auteur ; Christopher GILLBERG, Auteur ; Elisabeth FERNELL, Auteur . - p.2249-2258. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2249-2258 Mots-clés : Learning  Eye tracking  Scientific visualization  Bottom-up  Knowledge generation  Autism spectrum disorder  Diagnosis  Attention  Social dominance  Social hierarchies  Conflict  Goals Index. décimale : PER Périodiques Résumé : Looking at other children’s interactions provides rich learning opportunities for a small child. How children with autism look at other children is largely unknown. Using eye tracking, we studied gaze performance in children with autism and neurotypical comparison children while they were watching videos of semi-naturalistic social interactions between young children. Using a novel, bottom-up approach we identified event-related measures that distinguished between groups with high accuracy. The observed effects remained in a subset of the total sample matched on IQ, and were replicated across several different stimuli. The described method facilitates the detection of meaningful patterns in complex eye tracking data. Also, the approach significantly improves visualization, which will help investigators understand, illustrate, and generate new hypotheses. En ligne : http://dx.doi.org/10.1007/s10803-013-1776-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Practice Makes Improvement: How Adults with Autism Out-Perform Others in a Naturalistic Visual Search Task / Cleotilde GONZALEZ in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2259-2268 Titre : Practice Makes Improvement: How Adults with Autism Out-Perform Others in a Naturalistic Visual Search Task Type de document : Texte imprimé et/ou numérique Auteurs : Cleotilde GONZALEZ, Auteur ; Jolie M. MARTIN, Auteur ; Nancy J. MINSHEW, Auteur ; Marlene BEHRMANN, Auteur Article en page(s) : p.2259-2268 Langues : Anglais (eng) Mots-clés : Autism  Visual search  Luggage screening Index. décimale : PER Périodiques Résumé : People with autism spectrum disorder (ASD) often exhibit superior performance in visual search compared to others. However, most studies demonstrating this advantage have employed simple, uncluttered images with fully visible targets. We compare the performance of high-functioning adults with ASD and matched controls on a naturalistic luggage screening task. Although the two groups were equally accurate in detecting targets, the ASD adults improve in their correct elimination of target-absent bags faster than controls. This feature of their behavior is extremely important for many real-world monitoring tasks that require sustained attention for long time periods. Further analyses suggest that this improvement is attributable neither to the motor speed nor to the level of intelligence of the adults with ASD. These findings may have possible implications for employment opportunities of adult individuals with ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1772-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Practice Makes Improvement: How Adults with Autism Out-Perform Others in a Naturalistic Visual Search Task [Texte imprimé et/ou numérique] / Cleotilde GONZALEZ, Auteur ; Jolie M. MARTIN, Auteur ; Nancy J. MINSHEW, Auteur ; Marlene BEHRMANN, Auteur . - p.2259-2268. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2259-2268 Mots-clés : Autism  Visual search  Luggage screening Index. décimale : PER Périodiques Résumé : People with autism spectrum disorder (ASD) often exhibit superior performance in visual search compared to others. However, most studies demonstrating this advantage have employed simple, uncluttered images with fully visible targets. We compare the performance of high-functioning adults with ASD and matched controls on a naturalistic luggage screening task. Although the two groups were equally accurate in detecting targets, the ASD adults improve in their correct elimination of target-absent bags faster than controls. This feature of their behavior is extremely important for many real-world monitoring tasks that require sustained attention for long time periods. Further analyses suggest that this improvement is attributable neither to the motor speed nor to the level of intelligence of the adults with ASD. These findings may have possible implications for employment opportunities of adult individuals with ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1772-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

The Modified Checklist for Autism in Toddlers: Reliability in a Diverse Rural American Sample / Angela SCARPA in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2269-2279 Titre : The Modified Checklist for Autism in Toddlers: Reliability in a Diverse Rural American Sample Type de document : Texte imprimé et/ou numérique Auteurs : Angela SCARPA, Auteur ; Nuri M. REYES, Auteur ; Michelle A. PATRIQUIN, Auteur ; Jill LORENZI, Auteur ; Tyler A. HASSENFELDT, Auteur ; Varsha J. DESAI, Auteur ; Kathryn W. KERKERING, Auteur Article en page(s) : p.2269-2279 Langues : Anglais (eng) Mots-clés : M-CHAT  Autism screening  Reliability  Diverse populations Index. décimale : PER Périodiques Résumé : This study investigated the psychometric properties of the modified checklist for autism in toddlers (M-CHAT) in a diverse rural American low-socioeconomic status (SES) sample. Four hundred and forty-seven English (n = 335) and Spanish (n = 112) speaking caregivers completed the M-CHAT during their toddler’s 18- or 24-month well visit in a Southwest Virginia pediatric clinic. The M-CHAT did not show acceptable internal consistency in groups with low maternal education or minority status. Caregivers reporting low maternal education and minority status were more likely to endorse items suggestive of autism. These results indicate that the M-CHAT may require modifications to be more internally consistent and accurate across ethnic and educational groups in rural areas with low levels of SES. Recommendations to increase the utility of the M-CHAT are discussed. En ligne : http://dx.doi.org/10.1007/s10803-013-1779-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] The Modified Checklist for Autism in Toddlers: Reliability in a Diverse Rural American Sample [Texte imprimé et/ou numérique] / Angela SCARPA, Auteur ; Nuri M. REYES, Auteur ; Michelle A. PATRIQUIN, Auteur ; Jill LORENZI, Auteur ; Tyler A. HASSENFELDT, Auteur ; Varsha J. DESAI, Auteur ; Kathryn W. KERKERING, Auteur . - p.2269-2279. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2269-2279 Mots-clés : M-CHAT  Autism screening  Reliability  Diverse populations Index. décimale : PER Périodiques Résumé : This study investigated the psychometric properties of the modified checklist for autism in toddlers (M-CHAT) in a diverse rural American low-socioeconomic status (SES) sample. Four hundred and forty-seven English (n = 335) and Spanish (n = 112) speaking caregivers completed the M-CHAT during their toddler’s 18- or 24-month well visit in a Southwest Virginia pediatric clinic. The M-CHAT did not show acceptable internal consistency in groups with low maternal education or minority status. Caregivers reporting low maternal education and minority status were more likely to endorse items suggestive of autism. These results indicate that the M-CHAT may require modifications to be more internally consistent and accurate across ethnic and educational groups in rural areas with low levels of SES. Recommendations to increase the utility of the M-CHAT are discussed. En ligne : http://dx.doi.org/10.1007/s10803-013-1779-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

How to Use the ADI-R for Classifying Autism Spectrum Disorders? Psychometric Properties of Criteria from the Literature in 1,204 Dutch Children / Annelies A. DE BILDT in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2280-2294 Titre : How to Use the ADI-R for Classifying Autism Spectrum Disorders? Psychometric Properties of Criteria from the Literature in 1,204 Dutch Children Type de document : Texte imprimé et/ou numérique Auteurs : Annelies A. DE BILDT, Auteur ; Iris J. OOSTERLING, Auteur ; Natasja D. J. LANG, Auteur ; Sanne KUIJPER, Auteur ; Vera DEKKER, Auteur ; Sjoerd SYTEMA, Auteur ; Anoek M. OERLEMANS, Auteur ; Daphne J. STEIJN, Auteur ; Janne C. VISSER, Auteur ; Nanda N. ROMMELSE, Auteur ; Ruud B. MINDERAA, Auteur ; Herman VAN ENGELAND, Auteur ; Rutger Jan VAN DER GAAG, Auteur ; Jan K. BUITELAAR, Auteur ; Maretha V. JONGE, Auteur Article en page(s) : p.2280-2294 Langues : Anglais (eng) Mots-clés : ADI-R  Autism  ASD  Diagnosis  Classification  Validity Index. décimale : PER Périodiques Résumé : The algorithm of the Autism Diagnostic Interview-Revised provides criteria for autism versus non-autism according to DSM-IV. Criteria for the broader autism spectrum disorders are needed. This study investigated the validity of seven sets of criteria from the literature, in 1,204 Dutch children (aged 3–18 years) with and without mental retardation. The original criteria (Rutter et al. in ADI-R Autism Diagnostic Interview Revised. Manual. Western Psychological Services, Los Angeles, 2003) well discriminated ASD from non-ASD in MR. All other criteria (IMGSAC in Am Soc Hum Genet 69:570–581 2001; Sung et al. in Am J Hum Genet 76: 68–81, 2005; Risi et al. in J Am Acad Child Adolesc Psychiatry 45: 1094–1103, 2006) were sensitive at the cost of specificity, bearing the risk of overinclusiveness. In the group without MR, clinicians should decide whether sensitivity or specificity is aimed for, to choose the appropriate criteria. Including the Autism Diagnostic Observation Schedule revised algorithms in the classification, the specificity increases, at the cost of sensitivity. This study adds to a more valid judgment on which criteria to use for specific objectives. En ligne : http://dx.doi.org/10.1007/s10803-013-1783-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] How to Use the ADI-R for Classifying Autism Spectrum Disorders? Psychometric Properties of Criteria from the Literature in 1,204 Dutch Children [Texte imprimé et/ou numérique] / Annelies A. DE BILDT, Auteur ; Iris J. OOSTERLING, Auteur ; Natasja D. J. LANG, Auteur ; Sanne KUIJPER, Auteur ; Vera DEKKER, Auteur ; Sjoerd SYTEMA, Auteur ; Anoek M. OERLEMANS, Auteur ; Daphne J. STEIJN, Auteur ; Janne C. VISSER, Auteur ; Nanda N. ROMMELSE, Auteur ; Ruud B. MINDERAA, Auteur ; Herman VAN ENGELAND, Auteur ; Rutger Jan VAN DER GAAG, Auteur ; Jan K. BUITELAAR, Auteur ; Maretha V. JONGE, Auteur . - p.2280-2294. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2280-2294 Mots-clés : ADI-R  Autism  ASD  Diagnosis  Classification  Validity Index. décimale : PER Périodiques Résumé : The algorithm of the Autism Diagnostic Interview-Revised provides criteria for autism versus non-autism according to DSM-IV. Criteria for the broader autism spectrum disorders are needed. This study investigated the validity of seven sets of criteria from the literature, in 1,204 Dutch children (aged 3–18 years) with and without mental retardation. The original criteria (Rutter et al. in ADI-R Autism Diagnostic Interview Revised. Manual. Western Psychological Services, Los Angeles, 2003) well discriminated ASD from non-ASD in MR. All other criteria (IMGSAC in Am Soc Hum Genet 69:570–581 2001; Sung et al. in Am J Hum Genet 76: 68–81, 2005; Risi et al. in J Am Acad Child Adolesc Psychiatry 45: 1094–1103, 2006) were sensitive at the cost of specificity, bearing the risk of overinclusiveness. In the group without MR, clinicians should decide whether sensitivity or specificity is aimed for, to choose the appropriate criteria. Including the Autism Diagnostic Observation Schedule revised algorithms in the classification, the specificity increases, at the cost of sensitivity. This study adds to a more valid judgment on which criteria to use for specific objectives. En ligne : http://dx.doi.org/10.1007/s10803-013-1783-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

A Survey of Out-of-Pocket Expenditures for Children with Autism Spectrum Disorder in Israel / Raanan RAZ in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2295-2302 Titre : A Survey of Out-of-Pocket Expenditures for Children with Autism Spectrum Disorder in Israel Type de document : Texte imprimé et/ou numérique Auteurs : Raanan RAZ, Auteur ; Liat LERNER-GEVA, Auteur ; Odelia LEON, Auteur ; Gabriel CHODICK, Auteur ; Lidia V. GABIS, Auteur Article en page(s) : p.2295-2302 Langues : Anglais (eng) Mots-clés : Pervasive developmental disorders  Autism spectrum disorders  Health services  Out-of-pocket costs Index. décimale : PER Périodiques Résumé : We describe a survey of children with ASD aged 4–10 years. The main dependent variables were out-of-pocket expenditures for health services and hours of therapy. Multivariable logistic regression models were used in order to find independent predictors for service utilization. Parents of 178 of the children (87 %) agreed to participate. The average annual out-of-pocket cost was 8,288,withamedianof4,473 and a range of $0-89,754. Higher severity of ASD and a parent with an academic degree were associated with higher expenditure. Having at least one older sibling, siblings without developmental disorders, regular education setting, lower parent education and low income were associated with lower expenditure. En ligne : http://dx.doi.org/10.1007/s10803-013-1782-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] A Survey of Out-of-Pocket Expenditures for Children with Autism Spectrum Disorder in Israel [Texte imprimé et/ou numérique] / Raanan RAZ, Auteur ; Liat LERNER-GEVA, Auteur ; Odelia LEON, Auteur ; Gabriel CHODICK, Auteur ; Lidia V. GABIS, Auteur . - p.2295-2302. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2295-2302 Mots-clés : Pervasive developmental disorders  Autism spectrum disorders  Health services  Out-of-pocket costs Index. décimale : PER Périodiques Résumé : We describe a survey of children with ASD aged 4–10 years. The main dependent variables were out-of-pocket expenditures for health services and hours of therapy. Multivariable logistic regression models were used in order to find independent predictors for service utilization. Parents of 178 of the children (87 %) agreed to participate. The average annual out-of-pocket cost was 8,288,withamedianof4,473 and a range of $0-89,754. Higher severity of ASD and a parent with an academic degree were associated with higher expenditure. Having at least one older sibling, siblings without developmental disorders, regular education setting, lower parent education and low income were associated with lower expenditure. En ligne : http://dx.doi.org/10.1007/s10803-013-1782-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Associations Between Language Development and Skin Conductance Responses to Faces and Eye Gaze in Children with Autism Spectrum Disorder / Steven D. STAGG in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2303-2311 Titre : Associations Between Language Development and Skin Conductance Responses to Faces and Eye Gaze in Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Steven D. STAGG, Auteur ; Robert DAVIS, Auteur ; Pamela HEATON, Auteur Article en page(s) : p.2303-2311 Langues : Anglais (eng) Mots-clés : Language delay  Galvanic skin response  Language onset  Autism spectrum disorder  Faces  Eye-gaze Index. décimale : PER Périodiques Résumé : Attention to social stimuli is associated with language development, and arousal is associated with the increased viewing of stimuli. We investigated whether skin conductance responses (SCRs) are associated with language development in autism spectrum disorder (ASD): a population that shows abnormalities in both attention to others and language development. A sample of 32 children with ASD (7–15 year; M = 9 year) was divided into two groups, based on language onset histories. A typically developing comparison group consisted of 18 age and IQ matched children. SCRs were taken as the participants viewed faces. SCRs differentiated the ASD group based on language onset and were associated with abnormal attention to gaze in infancy and subsequent language development. En ligne : http://dx.doi.org/10.1007/s10803-013-1780-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Associations Between Language Development and Skin Conductance Responses to Faces and Eye Gaze in Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Steven D. STAGG, Auteur ; Robert DAVIS, Auteur ; Pamela HEATON, Auteur . - p.2303-2311. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2303-2311 Mots-clés : Language delay  Galvanic skin response  Language onset  Autism spectrum disorder  Faces  Eye-gaze Index. décimale : PER Périodiques Résumé : Attention to social stimuli is associated with language development, and arousal is associated with the increased viewing of stimuli. We investigated whether skin conductance responses (SCRs) are associated with language development in autism spectrum disorder (ASD): a population that shows abnormalities in both attention to others and language development. A sample of 32 children with ASD (7–15 year; M = 9 year) was divided into two groups, based on language onset histories. A typically developing comparison group consisted of 18 age and IQ matched children. SCRs were taken as the participants viewed faces. SCRs differentiated the ASD group based on language onset and were associated with abnormal attention to gaze in infancy and subsequent language development. En ligne : http://dx.doi.org/10.1007/s10803-013-1780-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Impaired Timing and Frequency Discrimination in High-functioning Autism Spectrum Disorders / Anjali BHATARA in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2312-2328 Titre : Impaired Timing and Frequency Discrimination in High-functioning Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Anjali BHATARA, Auteur ; Talin BABIKIAN, Auteur ; Elizabeth LAUGESON, Auteur ; Raffi TACHDJIAN, Auteur ; Yvonne S. SININGER, Auteur Article en page(s) : p.2312-2328 Langues : Anglais (eng) Mots-clés : Auditory perception  Psychophysics  Hyper-sensitivity  Asperger syndrome  High-functioning autism Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorders (ASD) frequently demonstrate preserved or enhanced frequency perception but impaired timing perception. The present study investigated the processing of spectral and temporal information in 12 adolescents with ASD and 15 age-matched controls. Participants completed two psychoacoustic tasks: one determined frequency difference limens, and the other determined gap detection thresholds. Results showed impaired frequency discrimination at the highest standard frequency in the ASD group but no overall difference between groups. However, when groups were defined by auditory hyper-sensitivity, a group difference arose. For the gap detection task, the ASD group demonstrated elevated thresholds. This supports previous research demonstrating a deficit in ASD in temporal perception and suggests a connection between hyper-sensitivity and frequency discrimination abilities. En ligne : http://dx.doi.org/10.1007/s10803-013-1778-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Impaired Timing and Frequency Discrimination in High-functioning Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Anjali BHATARA, Auteur ; Talin BABIKIAN, Auteur ; Elizabeth LAUGESON, Auteur ; Raffi TACHDJIAN, Auteur ; Yvonne S. SININGER, Auteur . - p.2312-2328. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2312-2328 Mots-clés : Auditory perception  Psychophysics  Hyper-sensitivity  Asperger syndrome  High-functioning autism Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorders (ASD) frequently demonstrate preserved or enhanced frequency perception but impaired timing perception. The present study investigated the processing of spectral and temporal information in 12 adolescents with ASD and 15 age-matched controls. Participants completed two psychoacoustic tasks: one determined frequency difference limens, and the other determined gap detection thresholds. Results showed impaired frequency discrimination at the highest standard frequency in the ASD group but no overall difference between groups. However, when groups were defined by auditory hyper-sensitivity, a group difference arose. For the gap detection task, the ASD group demonstrated elevated thresholds. This supports previous research demonstrating a deficit in ASD in temporal perception and suggests a connection between hyper-sensitivity and frequency discrimination abilities. En ligne : http://dx.doi.org/10.1007/s10803-013-1778-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Global/Local Processing in Autism: Not a Disability, but a Disinclination / Kami KOLDEWYN in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2329-2340 Titre : Global/Local Processing in Autism: Not a Disability, but a Disinclination Type de document : Texte imprimé et/ou numérique Auteurs : Kami KOLDEWYN, Auteur ; Yuhong V. JIANG, Auteur ; Sarah WEIGELT, Auteur ; Nancy KANWISHER, Auteur Article en page(s) : p.2329-2340 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Global/local processing  Global attention  Cognitive development Index. décimale : PER Périodiques Résumé : It is widely suggested that ASD is characterized by atypical local/global processing, but the published findings are contradictory. In an effort to resolve this question, we tested a large group of children on both a free-choice task and an instructed task using hierarchical local–global stimuli. We find that although children with autism showed a reduced preference to report global properties of a stimulus when given a choice, their ability to process global properties when instructed to do so is unimpaired. These findings support prior claims that people with ASD show a disinclination, not a disability, in global processing, and highlight the broader question of whether other characteristics of autism may also reflect disinclinations rather than disabilities. En ligne : http://dx.doi.org/10.1007/s10803-013-1777-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Global/Local Processing in Autism: Not a Disability, but a Disinclination [Texte imprimé et/ou numérique] / Kami KOLDEWYN, Auteur ; Yuhong V. JIANG, Auteur ; Sarah WEIGELT, Auteur ; Nancy KANWISHER, Auteur . - p.2329-2340. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2329-2340 Mots-clés : Autism spectrum disorder  Global/local processing  Global attention  Cognitive development Index. décimale : PER Périodiques Résumé : It is widely suggested that ASD is characterized by atypical local/global processing, but the published findings are contradictory. In an effort to resolve this question, we tested a large group of children on both a free-choice task and an instructed task using hierarchical local–global stimuli. We find that although children with autism showed a reduced preference to report global properties of a stimulus when given a choice, their ability to process global properties when instructed to do so is unimpaired. These findings support prior claims that people with ASD show a disinclination, not a disability, in global processing, and highlight the broader question of whether other characteristics of autism may also reflect disinclinations rather than disabilities. En ligne : http://dx.doi.org/10.1007/s10803-013-1777-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Exploring the Manifestations of Anxiety in Children with Autism Spectrum Disorders / Victoria HALLETT in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2341-2352 Titre : Exploring the Manifestations of Anxiety in Children with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Victoria HALLETT, Auteur ; Luc LECAVALIER, Auteur ; Denis G. SUKHODOLSKY, Auteur ; Noreen CIPRIANO, Auteur ; Michael G. AMAN, Auteur ; James T. MCCRACKEN, Auteur ; Christopher J. MCDOUGLE, Auteur ; Elaine TIERNEY, Auteur ; Bryan H. KING, Auteur ; Eric HOLLANDER, Auteur ; Linmarie SIKICH, Auteur ; Joel D. BREGMAN, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Craig DONNELLY, Auteur ; Lily KATSOVICH, Auteur ; Kimberly DUKES, Auteur ; Benedetto VITIELLO, Auteur ; Kenneth D. GADOW, Auteur ; Lawrence SCAHILL, Auteur Article en page(s) : p.2341-2352 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Anxiety  Measurement  Clinical Trials Index. décimale : PER Périodiques Résumé : This study explores the manifestation and measurement of anxiety symptoms in 415 children with ASDs on a 20-item, parent-rated, DSM-IV referenced anxiety scale. In both high and low-functioning children (IQ above vs. below 70), commonly endorsed items assessed restlessness, tension and sleep difficulties. Items requiring verbal expression of worry by the child were rarely endorsed. Higher anxiety was associated with functional language, IQ above 70 and higher scores on several other behavioral measures. Four underlying factors emerged: Generalized Anxiety, Separation Anxiety, Social Anxiety and Over-arousal. Our findings extend our understanding of anxiety across IQ in ASD and provide guidance for improving anxiety outcome measurement. En ligne : http://dx.doi.org/10.1007/s10803-013-1775-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Exploring the Manifestations of Anxiety in Children with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Victoria HALLETT, Auteur ; Luc LECAVALIER, Auteur ; Denis G. SUKHODOLSKY, Auteur ; Noreen CIPRIANO, Auteur ; Michael G. AMAN, Auteur ; James T. MCCRACKEN, Auteur ; Christopher J. MCDOUGLE, Auteur ; Elaine TIERNEY, Auteur ; Bryan H. KING, Auteur ; Eric HOLLANDER, Auteur ; Linmarie SIKICH, Auteur ; Joel D. BREGMAN, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Craig DONNELLY, Auteur ; Lily KATSOVICH, Auteur ; Kimberly DUKES, Auteur ; Benedetto VITIELLO, Auteur ; Kenneth D. GADOW, Auteur ; Lawrence SCAHILL, Auteur . - p.2341-2352. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2341-2352 Mots-clés : Autism spectrum disorders  Anxiety  Measurement  Clinical Trials Index. décimale : PER Périodiques Résumé : This study explores the manifestation and measurement of anxiety symptoms in 415 children with ASDs on a 20-item, parent-rated, DSM-IV referenced anxiety scale. In both high and low-functioning children (IQ above vs. below 70), commonly endorsed items assessed restlessness, tension and sleep difficulties. Items requiring verbal expression of worry by the child were rarely endorsed. Higher anxiety was associated with functional language, IQ above 70 and higher scores on several other behavioral measures. Four underlying factors emerged: Generalized Anxiety, Separation Anxiety, Social Anxiety and Over-arousal. Our findings extend our understanding of anxiety across IQ in ASD and provide guidance for improving anxiety outcome measurement. En ligne : http://dx.doi.org/10.1007/s10803-013-1775-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Perceiving Goals and Actions in Individuals with Autism Spectrum Disorders / Tiziana ZALLA in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2353-2365 Titre : Perceiving Goals and Actions in Individuals with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Tiziana ZALLA, Auteur ; Nelly LABRUYERE, Auteur ; Nicolas GEORGIEFF, Auteur Article en page(s) : p.2353-2365 Langues : Anglais (eng) Mots-clés : Action parsing  Intention  Episodic memory  Biological motion Index. décimale : PER Périodiques Résumé : In the present study, we investigated the ability to parse familiar sequences of action into meaningful events in young individuals with autism spectrum disorders (ASDs), as compared to young individuals with typical development (TD) and young individuals with moderate mental retardation or learning disabilities (MLDs). While viewing two videotaped movies, participants were requested to detect the boundary transitions between component events at both fine and coarse levels of the action hierarchical structure. Overall, reduced accuracy for event detection was found in participants with ASDs, relative to participants with TD, at both levels of action segmentation. The performance was, however, equally diminished in participants with ASDs and MLDs under the course-grained segmentation suggesting that difficulties to detect fine-grained events in ASDs cannot be explained by a general intellectual dysfunction. Reduced accuracy for event detection was related to diminished event recall, memory for event sequence and Theory of Mind abilities. We hypothesized that difficulties with event detection result from a deficit disrupting the on-line processing of kinematic features and physical changes of dynamic human actions. An impairment at the earlier stages of the event encoding process might contribute to deficits in episodic memory and social functioning in individuals with ASDs. En ligne : http://dx.doi.org/10.1007/s10803-013-1784-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Perceiving Goals and Actions in Individuals with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Tiziana ZALLA, Auteur ; Nelly LABRUYERE, Auteur ; Nicolas GEORGIEFF, Auteur . - p.2353-2365. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2353-2365 Mots-clés : Action parsing  Intention  Episodic memory  Biological motion Index. décimale : PER Périodiques Résumé : In the present study, we investigated the ability to parse familiar sequences of action into meaningful events in young individuals with autism spectrum disorders (ASDs), as compared to young individuals with typical development (TD) and young individuals with moderate mental retardation or learning disabilities (MLDs). While viewing two videotaped movies, participants were requested to detect the boundary transitions between component events at both fine and coarse levels of the action hierarchical structure. Overall, reduced accuracy for event detection was found in participants with ASDs, relative to participants with TD, at both levels of action segmentation. The performance was, however, equally diminished in participants with ASDs and MLDs under the course-grained segmentation suggesting that difficulties to detect fine-grained events in ASDs cannot be explained by a general intellectual dysfunction. Reduced accuracy for event detection was related to diminished event recall, memory for event sequence and Theory of Mind abilities. We hypothesized that difficulties with event detection result from a deficit disrupting the on-line processing of kinematic features and physical changes of dynamic human actions. An impairment at the earlier stages of the event encoding process might contribute to deficits in episodic memory and social functioning in individuals with ASDs. En ligne : http://dx.doi.org/10.1007/s10803-013-1784-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Early Signs of Autism in Toddlers: A Follow-Up Study in the Danish National Birth Cohort / Sanne LEMCKE in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2366-2375 Titre : Early Signs of Autism in Toddlers: A Follow-Up Study in the Danish National Birth Cohort Type de document : Texte imprimé et/ou numérique Auteurs : Sanne LEMCKE, Auteur ; Svend JUUL, Auteur ; Erik T. PARNER, Auteur ; Marlene B. LAURITSEN, Auteur ; Poul THORSEN, Auteur Article en page(s) : p.2366-2375 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Intellectual disability  Early signs  Parents’ interview  Follow-up study  Birth cohort Index. décimale : PER Périodiques Résumé : To identify possible early signs of autism spectrum disorder (ASD) within the Danish National Birth Cohort, we studied prospectively collected interviews from 76,441 mothers about their children’s development and behaviour at 6 and 18 months. In Danish national registries, 720 children with ASD and 231 children with intellectual disability (ID) were identified. At 6 months, associations between early signs and ASD or ID were found only in few areas. At 18 months social, language, and motor skills were delayed, and suspicion of vision and hearing problems were increased for both groups. Signs distinguishing ASD from ID were unclear, and the positive predictive values regarding ASD were below 10 % for individual predictors and aggregated risk scores. En ligne : http://dx.doi.org/10.1007/s10803-013-1785-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Early Signs of Autism in Toddlers: A Follow-Up Study in the Danish National Birth Cohort [Texte imprimé et/ou numérique] / Sanne LEMCKE, Auteur ; Svend JUUL, Auteur ; Erik T. PARNER, Auteur ; Marlene B. LAURITSEN, Auteur ; Poul THORSEN, Auteur . - p.2366-2375. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2366-2375 Mots-clés : Autism spectrum disorder  Intellectual disability  Early signs  Parents’ interview  Follow-up study  Birth cohort Index. décimale : PER Périodiques Résumé : To identify possible early signs of autism spectrum disorder (ASD) within the Danish National Birth Cohort, we studied prospectively collected interviews from 76,441 mothers about their children’s development and behaviour at 6 and 18 months. In Danish national registries, 720 children with ASD and 231 children with intellectual disability (ID) were identified. At 6 months, associations between early signs and ASD or ID were found only in few areas. At 18 months social, language, and motor skills were delayed, and suspicion of vision and hearing problems were increased for both groups. Signs distinguishing ASD from ID were unclear, and the positive predictive values regarding ASD were below 10 % for individual predictors and aggregated risk scores. En ligne : http://dx.doi.org/10.1007/s10803-013-1785-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Thinking About a Reader’s Mind: Fostering Communicative Clarity in the Compositions of Youth with Autism Spectrum Disorders / Michael GROSSMAN in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2376-2392 Titre : Thinking About a Reader’s Mind: Fostering Communicative Clarity in the Compositions of Youth with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Michael GROSSMAN, Auteur ; Joan PESKIN, Auteur ; Valerie SAN JUAN, Auteur Article en page(s) : p.2376-2392 Langues : Anglais (eng) Mots-clés : Autism  Asperger syndrome  Referential communication  Writing  Theory of mind  Intervention Index. décimale : PER Périodiques Résumé : A critical component of effective communication is the ability to consider the knowledge state of one’s audience, yet individuals with autism spectrum disorders (ASD) have difficulty representing the mental states of others. In the present study, youth with high-functioning ASD were trained to consider their reader’s knowledge states in their compositions using a novel computer-based task. After two training trials, participants who received visual feedback from a confederate demonstrated significantly greater communicative clarity on the training measure compared to a control group. The improvements from training transferred to similar and very different tasks, and were maintained approximately 6 weeks post-intervention. These results provide support for the sustained efficacy of a rapid and motivating communication intervention for youth with high-functioning ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1786-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Thinking About a Reader’s Mind: Fostering Communicative Clarity in the Compositions of Youth with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Michael GROSSMAN, Auteur ; Joan PESKIN, Auteur ; Valerie SAN JUAN, Auteur . - p.2376-2392. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2376-2392 Mots-clés : Autism  Asperger syndrome  Referential communication  Writing  Theory of mind  Intervention Index. décimale : PER Périodiques Résumé : A critical component of effective communication is the ability to consider the knowledge state of one’s audience, yet individuals with autism spectrum disorders (ASD) have difficulty representing the mental states of others. In the present study, youth with high-functioning ASD were trained to consider their reader’s knowledge states in their compositions using a novel computer-based task. After two training trials, participants who received visual feedback from a confederate demonstrated significantly greater communicative clarity on the training measure compared to a control group. The improvements from training transferred to similar and very different tasks, and were maintained approximately 6 weeks post-intervention. These results provide support for the sustained efficacy of a rapid and motivating communication intervention for youth with high-functioning ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1786-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Spatial and Identity Cues Differentially Affect Implicit Contextual Cueing in Adolescents and Adults with Autism Spectrum Disorder / Brittany G. TRAVERS in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2393-2404 Titre : Spatial and Identity Cues Differentially Affect Implicit Contextual Cueing in Adolescents and Adults with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Brittany G. TRAVERS, Auteur ; Patrick S. POWELL, Auteur ; Joanna L. MUSSEY, Auteur ; Laura G. KLINGER, Auteur ; Megan E. CRISLER, Auteur ; Mark R. KLINGER, Auteur Article en page(s) : p.2393-2404 Langues : Anglais (eng) Mots-clés : Implicit learning  Contextual cueing  Attention  Learning  Autism Index. décimale : PER Périodiques Résumé : The present studies examined implicit contextual cueing in adolescents and adults with Autism Spectrum Disorder (ASD). In Study 1, 16 individuals with ASD and 20 matched individuals with typical development completed a contextual cueing task using stimulus-identity cues. In Study 2, 12 individuals with ASD and 16 individuals with typical development completed a revised version of the contextual cueing task, using both stimulus-identity cues and global spatial-configuration cues. The results suggest that when only stimulus-identity cues were provided, individuals with ASD had difficulty with implicit contextual cueing (Study 1). However, when both stimulus-identity and spatial-configuration contextual cues were provided, individuals with ASD demonstrated successful contextual cueing (Study 2). Nuances in implicit learning and clinical implications are discussed. En ligne : http://dx.doi.org/10.1007/s10803-013-1787-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Spatial and Identity Cues Differentially Affect Implicit Contextual Cueing in Adolescents and Adults with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Brittany G. TRAVERS, Auteur ; Patrick S. POWELL, Auteur ; Joanna L. MUSSEY, Auteur ; Laura G. KLINGER, Auteur ; Megan E. CRISLER, Auteur ; Mark R. KLINGER, Auteur . - p.2393-2404. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2393-2404 Mots-clés : Implicit learning  Contextual cueing  Attention  Learning  Autism Index. décimale : PER Périodiques Résumé : The present studies examined implicit contextual cueing in adolescents and adults with Autism Spectrum Disorder (ASD). In Study 1, 16 individuals with ASD and 20 matched individuals with typical development completed a contextual cueing task using stimulus-identity cues. In Study 2, 12 individuals with ASD and 16 individuals with typical development completed a revised version of the contextual cueing task, using both stimulus-identity cues and global spatial-configuration cues. The results suggest that when only stimulus-identity cues were provided, individuals with ASD had difficulty with implicit contextual cueing (Study 1). However, when both stimulus-identity and spatial-configuration contextual cues were provided, individuals with ASD demonstrated successful contextual cueing (Study 2). Nuances in implicit learning and clinical implications are discussed. En ligne : http://dx.doi.org/10.1007/s10803-013-1787-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Cortisol Responsivity Differences in Children with Autism Spectrum Disorders During Free and Cooperative Play / Clayton W. SCHUPP in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2405-2417 Titre : Cortisol Responsivity Differences in Children with Autism Spectrum Disorders During Free and Cooperative Play Type de document : Texte imprimé et/ou numérique Auteurs : Clayton W. SCHUPP, Auteur ; David SIMON, Auteur ; Blythe A. CORBETT, Auteur Article en page(s) : p.2405-2417 Langues : Anglais (eng) Mots-clés : Autism  Cortisol  Play  Social  Stress  Responder Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) demonstrate significant heterogeneity in their profiles of social interaction and stress responsivity. We evaluated behavior and stress response in 52 male children ages 8–12 in a naturalistic playground interaction paradigm involving a child with ASD, a typically developing peer, and a same-age confederate. Younger children in the ASD group engaged in 5.8 times more approach behavior and showed a lower cortisol response than their older peers. Those that verbally initiated with their peers also showed a higher cortisol response. Older children with ASD exhibited the highest stress responsivity, while younger children with ASD showed more willingness to approach others without apparent stress. Intervening early and often may contribute to improvements in social engagement in youth with ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1790-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Cortisol Responsivity Differences in Children with Autism Spectrum Disorders During Free and Cooperative Play [Texte imprimé et/ou numérique] / Clayton W. SCHUPP, Auteur ; David SIMON, Auteur ; Blythe A. CORBETT, Auteur . - p.2405-2417. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2405-2417 Mots-clés : Autism  Cortisol  Play  Social  Stress  Responder Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) demonstrate significant heterogeneity in their profiles of social interaction and stress responsivity. We evaluated behavior and stress response in 52 male children ages 8–12 in a naturalistic playground interaction paradigm involving a child with ASD, a typically developing peer, and a same-age confederate. Younger children in the ASD group engaged in 5.8 times more approach behavior and showed a lower cortisol response than their older peers. Those that verbally initiated with their peers also showed a higher cortisol response. Older children with ASD exhibited the highest stress responsivity, while younger children with ASD showed more willingness to approach others without apparent stress. Intervening early and often may contribute to improvements in social engagement in youth with ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1790-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

The Broader Autism Phenotype and Friendships in Non-clinical Dyads / Allison L. WAINER in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2418-2425 Titre : The Broader Autism Phenotype and Friendships in Non-clinical Dyads Type de document : Texte imprimé et/ou numérique Auteurs : Allison L. WAINER, Auteur ; Nicole BLOCK, Auteur ; M. Brent DONNELLAN, Auteur ; Brooke R. INGERSOLL, Auteur Article en page(s) : p.2418-2425 Langues : Anglais (eng) Mots-clés : Broader autism phenotype  Friendships  Actor-partner interdependence model Index. décimale : PER Périodiques Résumé : The broader autism phenotype (BAP) is a set of subclinical traits qualitatively similar to those observed in autism spectrum disorders. The current study sought to elucidate the association between self- and informant-reports of the BAP and friendships, in a non-clinical sample of college student dyads. Self-informant agreement of the BAP and friendship similarity was evaluated, and the Actor-Partner Interdependence Model was used to test how both friends’ BAP characteristics jointly and uniquely contribute to the experiences of friendships. Results suggest self-informant agreement about the BAP, friendship closeness, quality, and conflict. Actor effects were observed for the BAP and friendship values, quality, conflict, and loneliness. Findings suggest that the BAP relates in meaningful ways to self-perceptions of friendship variables in the general population. En ligne : http://dx.doi.org/10.1007/s10803-013-1789-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] The Broader Autism Phenotype and Friendships in Non-clinical Dyads [Texte imprimé et/ou numérique] / Allison L. WAINER, Auteur ; Nicole BLOCK, Auteur ; M. Brent DONNELLAN, Auteur ; Brooke R. INGERSOLL, Auteur . - p.2418-2425. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2418-2425 Mots-clés : Broader autism phenotype  Friendships  Actor-partner interdependence model Index. décimale : PER Périodiques Résumé : The broader autism phenotype (BAP) is a set of subclinical traits qualitatively similar to those observed in autism spectrum disorders. The current study sought to elucidate the association between self- and informant-reports of the BAP and friendships, in a non-clinical sample of college student dyads. Self-informant agreement of the BAP and friendship similarity was evaluated, and the Actor-Partner Interdependence Model was used to test how both friends’ BAP characteristics jointly and uniquely contribute to the experiences of friendships. Results suggest self-informant agreement about the BAP, friendship closeness, quality, and conflict. Actor effects were observed for the BAP and friendship values, quality, conflict, and loneliness. Findings suggest that the BAP relates in meaningful ways to self-perceptions of friendship variables in the general population. En ligne : http://dx.doi.org/10.1007/s10803-013-1789-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Trajectories of Diurnal Cortisol in Mothers of Children with Autism and Other Developmental Disabilities: Relations to Health and Mental Health / Elisabeth M. DYKENS in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2426-2434 Titre : Trajectories of Diurnal Cortisol in Mothers of Children with Autism and Other Developmental Disabilities: Relations to Health and Mental Health Type de document : Texte imprimé et/ou numérique Auteurs : Elisabeth M. DYKENS, Auteur ; Warren LAMBERT, Auteur Article en page(s) : p.2426-2434 Langues : Anglais (eng) Mots-clés : Diurnal cortisol  Mothers of children with disabilities  Health  Mental health Index. décimale : PER Périodiques Résumé : This study used a stress biomarker, diurnal cortisol, to identify how elevated stress in mothers of children and adults with autism and other disabilities relates to their health and mental health. Based on semi-parametric, group-based trajectory analysis of 91 mothers, two distinctive cortisol trajectories emerged: blunted (63 %) or steep (37 %). Mothers in the blunted (vs. steep) trajectory had higher stress levels, lower health ratings, and 89 % of mothers of children with autism, and 53 % with other disabilities, belonged to this trajectory. Atypical cortisol awakening responses and evening rises were differentially associated with anxiety, depression, health problems and employment status. Stress-reducing interventions are needed for parents of children with autism and other disabilities that include biomarkers as indices of risk or treatment outcome. En ligne : http://dx.doi.org/10.1007/s10803-013-1791-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Trajectories of Diurnal Cortisol in Mothers of Children with Autism and Other Developmental Disabilities: Relations to Health and Mental Health [Texte imprimé et/ou numérique] / Elisabeth M. DYKENS, Auteur ; Warren LAMBERT, Auteur . - p.2426-2434. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2426-2434 Mots-clés : Diurnal cortisol  Mothers of children with disabilities  Health  Mental health Index. décimale : PER Périodiques Résumé : This study used a stress biomarker, diurnal cortisol, to identify how elevated stress in mothers of children and adults with autism and other disabilities relates to their health and mental health. Based on semi-parametric, group-based trajectory analysis of 91 mothers, two distinctive cortisol trajectories emerged: blunted (63 %) or steep (37 %). Mothers in the blunted (vs. steep) trajectory had higher stress levels, lower health ratings, and 89 % of mothers of children with autism, and 53 % with other disabilities, belonged to this trajectory. Atypical cortisol awakening responses and evening rises were differentially associated with anxiety, depression, health problems and employment status. Stress-reducing interventions are needed for parents of children with autism and other disabilities that include biomarkers as indices of risk or treatment outcome. En ligne : http://dx.doi.org/10.1007/s10803-013-1791-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Systematic Review and Meta-analysis of Pharmacological Treatment of the Symptoms of Attention-Deficit/Hyperactivity Disorder in Children with Pervasive Developmental Disorders / Brian REICHOW in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2435-2441 Titre : Systematic Review and Meta-analysis of Pharmacological Treatment of the Symptoms of Attention-Deficit/Hyperactivity Disorder in Children with Pervasive Developmental Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Brian REICHOW, Auteur ; Fred R. VOLKMAR, Auteur ; Michael H. BLOCH, Auteur Article en page(s) : p.2435-2441 Langues : Anglais (eng) Mots-clés : Autism  Pervasive developmental disorder  Attention deficit/hyperactivity disorder  Methylphenidate  Meta-analysis  Atomoxetine  Clonidine  ADHD  ASD  Autism spectrum disorder  PDD  PDD-NOS Index. décimale : PER Périodiques Résumé : Many children with pervasive developmental disorders (PDD) exhibit behaviors and symptoms of attention-deficit/hyperactivity disorder (ADHD). We sought to determine the relative efficacy of medications for treating ADHD symptoms in children with PDD by identifying all double-blind, randomized, placebo-controlled trials examining the efficacy of medications for treating ADHD symptoms in children with PDD. We located seven trials involving 225 children. A random effects meta-analysis of four methylphenidate trials showed methylphenidate to be effective for treating ADHD symptoms in children with PDD (ES = .67). Several adverse events were greater for children were taking methylphenidate compared to placebo. An individual trial of clonidine and two trials of atomoxetine suggest these agents may also be effective in treating ADHD symptoms in children with PDD. En ligne : http://dx.doi.org/10.1007/s10803-013-1793-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Systematic Review and Meta-analysis of Pharmacological Treatment of the Symptoms of Attention-Deficit/Hyperactivity Disorder in Children with Pervasive Developmental Disorders [Texte imprimé et/ou numérique] / Brian REICHOW, Auteur ; Fred R. VOLKMAR, Auteur ; Michael H. BLOCH, Auteur . - p.2435-2441. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2435-2441 Mots-clés : Autism  Pervasive developmental disorder  Attention deficit/hyperactivity disorder  Methylphenidate  Meta-analysis  Atomoxetine  Clonidine  ADHD  ASD  Autism spectrum disorder  PDD  PDD-NOS Index. décimale : PER Périodiques Résumé : Many children with pervasive developmental disorders (PDD) exhibit behaviors and symptoms of attention-deficit/hyperactivity disorder (ADHD). We sought to determine the relative efficacy of medications for treating ADHD symptoms in children with PDD by identifying all double-blind, randomized, placebo-controlled trials examining the efficacy of medications for treating ADHD symptoms in children with PDD. We located seven trials involving 225 children. A random effects meta-analysis of four methylphenidate trials showed methylphenidate to be effective for treating ADHD symptoms in children with PDD (ES = .67). Several adverse events were greater for children were taking methylphenidate compared to placebo. An individual trial of clonidine and two trials of atomoxetine suggest these agents may also be effective in treating ADHD symptoms in children with PDD. En ligne : http://dx.doi.org/10.1007/s10803-013-1793-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Psychopathology in Children and Adolescents with ASD Without Mental Retardation / Marta CAAMANO in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2442-2449 Titre : Psychopathology in Children and Adolescents with ASD Without Mental Retardation Type de document : Texte imprimé et/ou numérique Auteurs : Marta CAAMANO, Auteur ; Leticia BOADA, Auteur ; Jessica MERCHAN-NARANJO, Auteur ; Carmen MORENO, Auteur ; Cloe LLORENTE, Auteur ; Dolores MORENO, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur Article en page(s) : p.2442-2449 Langues : Anglais (eng) Mots-clés : Asperger syndrome  Psychopathology  Comorbidity  Adolescent  Developmental disorders Index. décimale : PER Périodiques Résumé : This study analyzes subclinical psychopathology in children and adolescents with autism spectrum disorders (ASD) without mental retardation with no comorbid disorder, assessed by an extensive general psychopathology interview. The K-SADS-PL was administered to a group of 25 patients with ASD (mean age = 12.80 ± 2.86 years) and 25 healthy controls (mean age 12.52 ± 2.86 years). Significant differences were found between patients with ASD and controls for the domains of: depressive disorder, anxiety separation disorder, agoraphobia and specific phobias, obsessive compulsive disorder (OCD), and attention deficit hyperactivity disorder (ADHD). In patients without a comorbid disorder, we found a profile of subclinical disturbances that suggest high risk for comorbid psychiatric conditions derived from the presence of subthreshold symptomatology. En ligne : http://dx.doi.org/10.1007/s10803-013-1792-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Psychopathology in Children and Adolescents with ASD Without Mental Retardation [Texte imprimé et/ou numérique] / Marta CAAMANO, Auteur ; Leticia BOADA, Auteur ; Jessica MERCHAN-NARANJO, Auteur ; Carmen MORENO, Auteur ; Cloe LLORENTE, Auteur ; Dolores MORENO, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur . - p.2442-2449. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2442-2449 Mots-clés : Asperger syndrome  Psychopathology  Comorbidity  Adolescent  Developmental disorders Index. décimale : PER Périodiques Résumé : This study analyzes subclinical psychopathology in children and adolescents with autism spectrum disorders (ASD) without mental retardation with no comorbid disorder, assessed by an extensive general psychopathology interview. The K-SADS-PL was administered to a group of 25 patients with ASD (mean age = 12.80 ± 2.86 years) and 25 healthy controls (mean age 12.52 ± 2.86 years). Significant differences were found between patients with ASD and controls for the domains of: depressive disorder, anxiety separation disorder, agoraphobia and specific phobias, obsessive compulsive disorder (OCD), and attention deficit hyperactivity disorder (ADHD). In patients without a comorbid disorder, we found a profile of subclinical disturbances that suggest high risk for comorbid psychiatric conditions derived from the presence of subthreshold symptomatology. En ligne : http://dx.doi.org/10.1007/s10803-013-1792-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

The Phenomenology and Clinical Correlates of Suicidal Thoughts and Behaviors in Youth with Autism Spectrum Disorders / Eric A. STORCH in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2450-2459 Titre : The Phenomenology and Clinical Correlates of Suicidal Thoughts and Behaviors in Youth with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Eric A. STORCH, Auteur ; Michael L. SULKOWSKI, Auteur ; Josh NADEAU, Auteur ; Adam B. LEWIN, Auteur ; Elysse B. ARNOLD, Auteur ; P. Jane MUTCH, Auteur ; Anna M. JONES, Auteur ; Tanya K. MURPHY, Auteur Article en page(s) : p.2450-2459 Langues : Anglais (eng) Mots-clés : Suicide  Autism spectrum disorders  Pervasive developmental disorder  Asperger’s disorder  Depression Index. décimale : PER Périodiques Résumé : This study investigated the phenomenology and clinical correlates of suicidal thoughts and behaviors in youth with ASD (N = 102; range 7–16 years). The presence of suicidal thoughts and behavior was assessed through the Anxiety Disorders Interview Schedule-Child and Parent Versions. Children and parents completed measures of anxiety severity, functional impairment, and behavioral and emotional problems. Approximately 11 % of youth displayed suicidal thoughts and behaviors. Children with autism were more likely to have suicidal thoughts and behaviors whereas children with Asperger’s disorder were less likely. Suicidal thoughts and behaviors were associated with the presence of depression and post-traumatic stress disorder. Overall, results suggest that suicidal thoughts and behaviors are common in youth with ASD, and may be related to depression and trauma. En ligne : http://dx.doi.org/10.1007/s10803-013-1795-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] The Phenomenology and Clinical Correlates of Suicidal Thoughts and Behaviors in Youth with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Eric A. STORCH, Auteur ; Michael L. SULKOWSKI, Auteur ; Josh NADEAU, Auteur ; Adam B. LEWIN, Auteur ; Elysse B. ARNOLD, Auteur ; P. Jane MUTCH, Auteur ; Anna M. JONES, Auteur ; Tanya K. MURPHY, Auteur . - p.2450-2459. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2450-2459 Mots-clés : Suicide  Autism spectrum disorders  Pervasive developmental disorder  Asperger’s disorder  Depression Index. décimale : PER Périodiques Résumé : This study investigated the phenomenology and clinical correlates of suicidal thoughts and behaviors in youth with ASD (N = 102; range 7–16 years). The presence of suicidal thoughts and behavior was assessed through the Anxiety Disorders Interview Schedule-Child and Parent Versions. Children and parents completed measures of anxiety severity, functional impairment, and behavioral and emotional problems. Approximately 11 % of youth displayed suicidal thoughts and behaviors. Children with autism were more likely to have suicidal thoughts and behaviors whereas children with Asperger’s disorder were less likely. Suicidal thoughts and behaviors were associated with the presence of depression and post-traumatic stress disorder. Overall, results suggest that suicidal thoughts and behaviors are common in youth with ASD, and may be related to depression and trauma. En ligne : http://dx.doi.org/10.1007/s10803-013-1795-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Utility of the Psychoeducational Profile-3 for Assessing Cognitive and Language Skills of Children with Autism Spectrum Disorders / Mandy L. FULTON in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2460-2471 Titre : Utility of the Psychoeducational Profile-3 for Assessing Cognitive and Language Skills of Children with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Mandy L. FULTON, Auteur ; Barbara D’ENTREMONT, Auteur Article en page(s) : p.2460-2471 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Psychoeducational Profile-3  Psychometric properties  Diagnostic symptomatology Index. décimale : PER Périodiques Résumé : The Psychoeducational Profile-3’s (PEP-3) ability to estimate cognitive and language skills of 136 children (20–75 months) with autism spectrum disorders (ASDs) across a range of functioning, and the association between the PEP-3 and ASD symptomatology was examined using retrospective data. PEP-3 cognitive and language measures were positively correlated with similar measures on the Child Development Inventory, the Merrill-Palmer Revised, and the Vineland Adaptive Behaviour Scale-2. The PEP-3 sometimes provided higher or lower estimates than other measures. Significant differences were found between diagnostic groups on PEP-3 cognitive and language measures. PEP-3 cognitive scores correlated positively with scores on the Autism Diagnostic Observation Schedule. Findings support the use of the PEP-3 to measure cognition and language in children with ASDs. En ligne : http://dx.doi.org/10.1007/s10803-013-1794-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Utility of the Psychoeducational Profile-3 for Assessing Cognitive and Language Skills of Children with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Mandy L. FULTON, Auteur ; Barbara D’ENTREMONT, Auteur . - p.2460-2471. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2460-2471 Mots-clés : Autism spectrum disorders  Psychoeducational Profile-3  Psychometric properties  Diagnostic symptomatology Index. décimale : PER Périodiques Résumé : The Psychoeducational Profile-3’s (PEP-3) ability to estimate cognitive and language skills of 136 children (20–75 months) with autism spectrum disorders (ASDs) across a range of functioning, and the association between the PEP-3 and ASD symptomatology was examined using retrospective data. PEP-3 cognitive and language measures were positively correlated with similar measures on the Child Development Inventory, the Merrill-Palmer Revised, and the Vineland Adaptive Behaviour Scale-2. The PEP-3 sometimes provided higher or lower estimates than other measures. Significant differences were found between diagnostic groups on PEP-3 cognitive and language measures. PEP-3 cognitive scores correlated positively with scores on the Autism Diagnostic Observation Schedule. Findings support the use of the PEP-3 to measure cognition and language in children with ASDs. En ligne : http://dx.doi.org/10.1007/s10803-013-1794-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

JobTIPS: A Transition to Employment Program for Individuals with Autism Spectrum Disorders / Dorothy C. STRICKLAND in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2472-2483 Titre : JobTIPS: A Transition to Employment Program for Individuals with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Dorothy C. STRICKLAND, Auteur ; Claire D. COLES, Auteur ; Louise B. SOUTHERN, Auteur Article en page(s) : p.2472-2483 Langues : Anglais (eng) Mots-clés : Autism  Interviewing  JobTIPS  Employment  Theory of Mind Index. décimale : PER Périodiques Résumé : This study evaluated the effectiveness of an internet accessed training program that included Theory of Mind-based guidance, video models, visual supports, and virtual reality practice sessions in teaching appropriate job interview skills to individuals with high functioning Autism Spectrum Disorders. In a randomized study, twenty-two youth, ages 16–19, were evaluated during two employment interviews. Half received a training intervention following the initial interview and the half who served as a contrast group did not. Their performance pre and post intervention was assessed by four independent raters using a scale that included evaluation of both Content and Delivery. Results suggest that youth who completed the JobTIPS employment program demonstrated significantly more effective verbal content skills than those who did not. En ligne : http://dx.doi.org/10.1007/s10803-013-1800-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] JobTIPS: A Transition to Employment Program for Individuals with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Dorothy C. STRICKLAND, Auteur ; Claire D. COLES, Auteur ; Louise B. SOUTHERN, Auteur . - p.2472-2483. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2472-2483 Mots-clés : Autism  Interviewing  JobTIPS  Employment  Theory of Mind Index. décimale : PER Périodiques Résumé : This study evaluated the effectiveness of an internet accessed training program that included Theory of Mind-based guidance, video models, visual supports, and virtual reality practice sessions in teaching appropriate job interview skills to individuals with high functioning Autism Spectrum Disorders. In a randomized study, twenty-two youth, ages 16–19, were evaluated during two employment interviews. Half received a training intervention following the initial interview and the half who served as a contrast group did not. Their performance pre and post intervention was assessed by four independent raters using a scale that included evaluation of both Content and Delivery. Results suggest that youth who completed the JobTIPS employment program demonstrated significantly more effective verbal content skills than those who did not. En ligne : http://dx.doi.org/10.1007/s10803-013-1800-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Brief Report: Regression Timing and Associated Features in MECP2 Duplication Syndrome / S. U. PETERS in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2484-2490 Titre : Brief Report: Regression Timing and Associated Features in MECP2 Duplication Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : S. U. PETERS, Auteur ; Rachel J. HUNDLEY, Auteur ; A. K. WILSON, Auteur ; Claudia M. B. CARVALHO, Auteur ; James R. LUPSKI, Auteur ; M. B. RAMOCKI, Auteur Article en page(s) : p.2484-2490 Langues : Anglais (eng) Mots-clés : Regression  MECP2  Seizures Index. décimale : PER Périodiques Résumé : The aim of this study was to determine the frequency, timing, and associated features of developmental regression in MECP2 duplication syndrome. We also examined whether duplication size was associated with regression. Comprehensive psychological evaluations were used to assess 17 boys with MECP2 duplication syndrome. Information about regression was gathered via parent report. Eight of 17 boys exhibited regression in language skills, while seven of 17 exhibited regression in other skill areas. Regression in “other skill” areas coincided with seizure onset and with a prior autism diagnosis in six of seven participants. Regression was not associated with duplication size. Questions remain as to why some boys regress, and future work is necessary to understand the underlying mechanism(s) that causes regression. En ligne : http://dx.doi.org/10.1007/s10803-013-1796-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Brief Report: Regression Timing and Associated Features in MECP2 Duplication Syndrome [Texte imprimé et/ou numérique] / S. U. PETERS, Auteur ; Rachel J. HUNDLEY, Auteur ; A. K. WILSON, Auteur ; Claudia M. B. CARVALHO, Auteur ; James R. LUPSKI, Auteur ; M. B. RAMOCKI, Auteur . - p.2484-2490. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2484-2490 Mots-clés : Regression  MECP2  Seizures Index. décimale : PER Périodiques Résumé : The aim of this study was to determine the frequency, timing, and associated features of developmental regression in MECP2 duplication syndrome. We also examined whether duplication size was associated with regression. Comprehensive psychological evaluations were used to assess 17 boys with MECP2 duplication syndrome. Information about regression was gathered via parent report. Eight of 17 boys exhibited regression in language skills, while seven of 17 exhibited regression in other skill areas. Regression in “other skill” areas coincided with seizure onset and with a prior autism diagnosis in six of seven participants. Regression was not associated with duplication size. Questions remain as to why some boys regress, and future work is necessary to understand the underlying mechanism(s) that causes regression. En ligne : http://dx.doi.org/10.1007/s10803-013-1796-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215