Gene × Environment effects of serotonin transporter, dopamine receptor D4, and monoamine oxidase A genes with contextual and parenting risk factors on symptoms of oppositional defiant disorder, anxiety, and depression in a community sample of 4-year-old children / John V. LAVIGNE in Development and Psychopathology, 25-2 (May 2013)  

Public ISBD [article]  inDevelopment and Psychopathology > 25-2 (May 2013) . - p.555-575 Titre : Gene × Environment effects of serotonin transporter, dopamine receptor D4, and monoamine oxidase A genes with contextual and parenting risk factors on symptoms of oppositional defiant disorder, anxiety, and depression in a community sample of 4-year-old children Type de document : Texte imprimé et/ou numérique Auteurs : John V. LAVIGNE, Auteur ; Laura B. K. HERZING, Auteur ; Edwin H. Jr COOK, Auteur ; Susan A. LEBAILLY, Auteur ; Karen R. GOUZE, Auteur ; Joyce HOPKINS, Auteur ; Fred B. BRYANT, Auteur Article en page(s) : p.555-575 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Genetic factors can play a key role in the multiple level of analyses approach to understanding the development of child psychopathology. The present study examined gene–environment correlations and Gene × Environment interactions for polymorphisms of three target genes, the serotonin transporter gene, the D4 dopamine receptor gene, and the monoamine oxidase A gene in relation to symptoms of anxiety, depression, and oppositional behavior. Saliva samples were collected from 175 non-Hispanic White, 4-year-old children. Psychosocial risk factors included socioeconomic status, life stress, caretaker depression, parental support, hostility, and scaffolding skills. In comparison with the short forms (s/s, s/l) of the serotonin transporter linked polymorphic repeat, the long form (l/l) was associated with greater increases in symptoms of oppositional defiant disorder in interaction with family stress and with greater increases in symptoms of child depression and anxiety in interaction with caretaker depression, family conflict, and socioeconomic status. In boys, low-activity monoamine oxidase A gene was associated with increases in child anxiety and depression in interaction with caretaker depression, hostility, family conflict, and family stress. The results highlight the important of gene–environment interplay in the development of symptoms of child psychopathology in young children. En ligne : http://dx.doi.org/10.1017/S0954579412001241 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=199 [article] Gene × Environment effects of serotonin transporter, dopamine receptor D4, and monoamine oxidase A genes with contextual and parenting risk factors on symptoms of oppositional defiant disorder, anxiety, and depression in a community sample of 4-year-old children [Texte imprimé et/ou numérique] / John V. LAVIGNE, Auteur ; Laura B. K. HERZING, Auteur ; Edwin H. Jr COOK, Auteur ; Susan A. LEBAILLY, Auteur ; Karen R. GOUZE, Auteur ; Joyce HOPKINS, Auteur ; Fred B. BRYANT, Auteur . - p.555-575. Langues : Anglais (eng) in Development and Psychopathology > 25-2 (May 2013) . - p.555-575 Index. décimale : PER Périodiques Résumé : Genetic factors can play a key role in the multiple level of analyses approach to understanding the development of child psychopathology. The present study examined gene–environment correlations and Gene × Environment interactions for polymorphisms of three target genes, the serotonin transporter gene, the D4 dopamine receptor gene, and the monoamine oxidase A gene in relation to symptoms of anxiety, depression, and oppositional behavior. Saliva samples were collected from 175 non-Hispanic White, 4-year-old children. Psychosocial risk factors included socioeconomic status, life stress, caretaker depression, parental support, hostility, and scaffolding skills. In comparison with the short forms (s/s, s/l) of the serotonin transporter linked polymorphic repeat, the long form (l/l) was associated with greater increases in symptoms of oppositional defiant disorder in interaction with family stress and with greater increases in symptoms of child depression and anxiety in interaction with caretaker depression, family conflict, and socioeconomic status. In boys, low-activity monoamine oxidase A gene was associated with increases in child anxiety and depression in interaction with caretaker depression, hostility, family conflict, and family stress. The results highlight the important of gene–environment interplay in the development of symptoms of child psychopathology in young children. En ligne : http://dx.doi.org/10.1017/S0954579412001241 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=199

A multidomain cascade model of early childhood risk factors associated with oppositional defiant disorder symptoms in a community sample of 6-year-olds / John V. LAVIGNE in Development and Psychopathology, 28-4 pt2 (November 2016)  

Public ISBD [article]  inDevelopment and Psychopathology > 28-4 pt2 (November 2016) . - p.1547-1562 Titre : A multidomain cascade model of early childhood risk factors associated with oppositional defiant disorder symptoms in a community sample of 6-year-olds Type de document : Texte imprimé et/ou numérique Auteurs : John V. LAVIGNE, Auteur ; Karen R. GOUZE, Auteur ; Joyce HOPKINS, Auteur ; Fred B. BRYANT, Auteur Article en page(s) : p.1547-1562 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The present study examined a cascade model of age 4 and 5 contextual, parent, parenting, and child factors on symptoms of oppositional defiant disorder (ODD) at age 6 in a diverse community sample of 796 children. Contextual factors include socioeconomic status, family stress, and conflict; parent factors included parental depression; parenting factors included parental hostility, support, and scaffolding skills; child factors included child effortful control (EC), negative affect (NA), and sensory regulation. Direct effects of age 5 conflict, hostility, scaffolding, EC, and NA were found. Significant indirect, cascading effects on age 6 ODD symptom levels were noted for age 4 socioeconomic status via age 5 conflict and scaffolding skills; age 4 parental depression via age 5 child NA; age 4 parental hostility and support via age 5 EC; age 4 support via age 5 EC; and age 4 attachment via age 5 EC. Parenting contributed to EC, and the age 5 EC effects on subsequent ODD symptom levels were distinct from age 5 parental contributions. Scaffolding and ODD symptoms may have a reciprocal relationship. These results highlight the importance of using a multidomain model to examine factors associated with ODD symptoms early in the child's grammar school years. En ligne : http://dx.doi.org/10.1017/s0954579415001194 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294 [article] A multidomain cascade model of early childhood risk factors associated with oppositional defiant disorder symptoms in a community sample of 6-year-olds [Texte imprimé et/ou numérique] / John V. LAVIGNE, Auteur ; Karen R. GOUZE, Auteur ; Joyce HOPKINS, Auteur ; Fred B. BRYANT, Auteur . - p.1547-1562. Langues : Anglais (eng) in Development and Psychopathology > 28-4 pt2 (November 2016) . - p.1547-1562 Index. décimale : PER Périodiques Résumé : The present study examined a cascade model of age 4 and 5 contextual, parent, parenting, and child factors on symptoms of oppositional defiant disorder (ODD) at age 6 in a diverse community sample of 796 children. Contextual factors include socioeconomic status, family stress, and conflict; parent factors included parental depression; parenting factors included parental hostility, support, and scaffolding skills; child factors included child effortful control (EC), negative affect (NA), and sensory regulation. Direct effects of age 5 conflict, hostility, scaffolding, EC, and NA were found. Significant indirect, cascading effects on age 6 ODD symptom levels were noted for age 4 socioeconomic status via age 5 conflict and scaffolding skills; age 4 parental depression via age 5 child NA; age 4 parental hostility and support via age 5 EC; age 4 support via age 5 EC; and age 4 attachment via age 5 EC. Parenting contributed to EC, and the age 5 EC effects on subsequent ODD symptom levels were distinct from age 5 parental contributions. Scaffolding and ODD symptoms may have a reciprocal relationship. These results highlight the importance of using a multidomain model to examine factors associated with ODD symptoms early in the child's grammar school years. En ligne : http://dx.doi.org/10.1017/s0954579415001194 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294

The Prevalence of ADHD, ODD, Depression, and Anxiety in a Community Sample of 4-Year-Olds / John V. LAVIGNE in Journal of Clinical Child & Adolescent Psychology, 38-3 (May 2009)  

Public ISBD [article]  inJournal of Clinical Child & Adolescent Psychology > 38-3 (May 2009) . - p.315-328 Titre : The Prevalence of ADHD, ODD, Depression, and Anxiety in a Community Sample of 4-Year-Olds Type de document : Texte imprimé et/ou numérique Auteurs : John V. LAVIGNE, Auteur ; Susan A. LEBAILLY, Auteur ; Joyce HOPKINS, Auteur ; Karen R. GOUZE, Auteur ; Helen J. BINNS, Auteur Année de publication : 2009 Article en page(s) : p.315-328 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Few studies have examined the epidemiology of preschoolers' psychopathology. This study included 796 4-year-old children recruited from schools and pediatric practices in a diverse, urban area. Psychiatric disorder was assessed by a structured interview adapted for preschool children and by questionnaire. The most common disorders were oppositional defiant disorder (ODD) and attention deficit hyperactivity disorder (ADHD). Generalized anxiety disorder (GAD) and depressive disorders were reported in less than 1% of the sample. Race/ethnicity differences were not significant. Gender differences showed ADHD-inattentive type more common among boys, with no gender differences for GAD, major depressive disorder, dysthymia, separation anxiety disorder, or ODD at any level of impairment. The overall comorbidity rate was 6.4%. Approximately 3% of individuals receiving a diagnosis had received mental health services. En ligne : http://dx.doi.org/10.1080/15374410902851382 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=756 [article] The Prevalence of ADHD, ODD, Depression, and Anxiety in a Community Sample of 4-Year-Olds [Texte imprimé et/ou numérique] / John V. LAVIGNE, Auteur ; Susan A. LEBAILLY, Auteur ; Joyce HOPKINS, Auteur ; Karen R. GOUZE, Auteur ; Helen J. BINNS, Auteur . - 2009 . - p.315-328. Langues : Anglais (eng) in Journal of Clinical Child & Adolescent Psychology > 38-3 (May 2009) . - p.315-328 Index. décimale : PER Périodiques Résumé : Few studies have examined the epidemiology of preschoolers' psychopathology. This study included 796 4-year-old children recruited from schools and pediatric practices in a diverse, urban area. Psychiatric disorder was assessed by a structured interview adapted for preschool children and by questionnaire. The most common disorders were oppositional defiant disorder (ODD) and attention deficit hyperactivity disorder (ADHD). Generalized anxiety disorder (GAD) and depressive disorders were reported in less than 1% of the sample. Race/ethnicity differences were not significant. Gender differences showed ADHD-inattentive type more common among boys, with no gender differences for GAD, major depressive disorder, dysthymia, separation anxiety disorder, or ODD at any level of impairment. The overall comorbidity rate was 6.4%. Approximately 3% of individuals receiving a diagnosis had received mental health services. En ligne : http://dx.doi.org/10.1080/15374410902851382 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=756

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