Cerebellum, Language, and Cognition in Autism and Specific Language Impairment / Steven M. HODGE in Journal of Autism and Developmental Disorders, 40-3 (March 2010)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 40-3 (March 2010) . - p.300-316 Titre : Cerebellum, Language, and Cognition in Autism and Specific Language Impairment Type de document : Texte imprimé et/ou numérique Auteurs : Steven M. HODGE, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Jean A. FRAZIER, Auteur ; James HOWARD, Auteur ; David N. KENNEDY, Auteur ; Nikos MAKRIS, Auteur ; Verne S. Jr CAVINESS, Auteur ; Lauren M. MCGRATH, Auteur ; Shelly D. STEELE, Auteur ; Gordon J. HARRIS, Auteur Année de publication : 2010 Article en page(s) : p.300-316 Langues : Anglais (eng) Mots-clés : Autism Specific-language-impairment Cerebellum Broca’s-area Asymmetry Index. décimale : PER Périodiques Résumé : We performed cerebellum segmentation and parcellation on magnetic resonance images from right-handed boys, aged 6–13 years, including 22 boys with autism [16 with language impairment (ALI)], 9 boys with Specific Language Impairment (SLI), and 11 normal controls. Language-impaired groups had reversed asymmetry relative to unimpaired groups in posterior-lateral cerebellar lobule VIIIA (right side larger in unimpaired groups, left side larger in ALI and SLI), contralateral to previous findings in inferior frontal cortex language areas. Lobule VIIA Crus I was smaller in SLI than in ALI. Vermis volume, particularly anterior I–V, was decreased in language-impaired groups. Language performance test scores correlated with lobule VIIIA asymmetry and with anterior vermis volume. These findings suggest ALI and SLI subjects show abnormalities in neurodevelopment of fronto-corticocerebellar circuits that manage motor control and the processing of language, cognition, working memory, and attention. En ligne : http://dx.doi.org/10.1007/s10803-009-0872-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=966 [article] Cerebellum, Language, and Cognition in Autism and Specific Language Impairment [Texte imprimé et/ou numérique] / Steven M. HODGE, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Jean A. FRAZIER, Auteur ; James HOWARD, Auteur ; David N. KENNEDY, Auteur ; Nikos MAKRIS, Auteur ; Verne S. Jr CAVINESS, Auteur ; Lauren M. MCGRATH, Auteur ; Shelly D. STEELE, Auteur ; Gordon J. HARRIS, Auteur . - 2010 . - p.300-316. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 40-3 (March 2010) . - p.300-316 Mots-clés : Autism Specific-language-impairment Cerebellum Broca’s-area Asymmetry Index. décimale : PER Périodiques Résumé : We performed cerebellum segmentation and parcellation on magnetic resonance images from right-handed boys, aged 6–13 years, including 22 boys with autism [16 with language impairment (ALI)], 9 boys with Specific Language Impairment (SLI), and 11 normal controls. Language-impaired groups had reversed asymmetry relative to unimpaired groups in posterior-lateral cerebellar lobule VIIIA (right side larger in unimpaired groups, left side larger in ALI and SLI), contralateral to previous findings in inferior frontal cortex language areas. Lobule VIIA Crus I was smaller in SLI than in ALI. Vermis volume, particularly anterior I–V, was decreased in language-impaired groups. Language performance test scores correlated with lobule VIIIA asymmetry and with anterior vermis volume. These findings suggest ALI and SLI subjects show abnormalities in neurodevelopment of fronto-corticocerebellar circuits that manage motor control and the processing of language, cognition, working memory, and attention. En ligne : http://dx.doi.org/10.1007/s10803-009-0872-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=966

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