Dépouillements

Facing the challenge of teaching emotions to individuals with low- and high-functioning autism using a new Serious game: a pilot study / Sylvie SERRET in Molecular Autism, (July 2014)  

Public ISBD [article]  inMolecular Autism > (July 2014) . - p.1-17 Titre : Facing the challenge of teaching emotions to individuals with low- and high-functioning autism using a new Serious game: a pilot study Type de document : Texte imprimé et/ou numérique Auteurs : Sylvie SERRET, Auteur ; Stéphanie HUN, Auteur ; Galina IAKIMOVA, Auteur ; José LOZADA, Auteur ; Margarita ANASTASSOVA, Auteur ; Andreia SANTOS, Auteur ; Stephanie VESPERINI, Auteur ; Florence ASKENAZY, Auteur Article en page(s) : p.1-17 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : It is widely accepted that emotion processing difficulties are involved in Autism Spectrum Conditions (ASC). An increasing number of studies have focused on the development of training programs and have shown promising results. However, most of these programs are appropriate for individuals with high-functioning ASC (HFA) but exclude individuals with low-functioning ASC (LFA). We have developed a computer-based game called JeStiMulE based on logical skills to teach emotions to individuals with ASC, independently of their age, intellectual, verbal and academic level. En ligne : http://dx.doi.org/10.1186/2040-2392-5-37 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276 [article] Facing the challenge of teaching emotions to individuals with low- and high-functioning autism using a new Serious game: a pilot study [Texte imprimé et/ou numérique] / Sylvie SERRET, Auteur ; Stéphanie HUN, Auteur ; Galina IAKIMOVA, Auteur ; José LOZADA, Auteur ; Margarita ANASTASSOVA, Auteur ; Andreia SANTOS, Auteur ; Stephanie VESPERINI, Auteur ; Florence ASKENAZY, Auteur . - p.1-17. Langues : Anglais (eng) in Molecular Autism > (July 2014) . - p.1-17 Index. décimale : PER Périodiques Résumé : It is widely accepted that emotion processing difficulties are involved in Autism Spectrum Conditions (ASC). An increasing number of studies have focused on the development of training programs and have shown promising results. However, most of these programs are appropriate for individuals with high-functioning ASC (HFA) but exclude individuals with low-functioning ASC (LFA). We have developed a computer-based game called JeStiMulE based on logical skills to teach emotions to individuals with ASC, independently of their age, intellectual, verbal and academic level. En ligne : http://dx.doi.org/10.1186/2040-2392-5-37 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276

Integrative proteomic analysis of the NMDA NR1 knockdown mouse model reveals effects on central and peripheral pathways associated with schizophrenia and autism spectrum disorders / Hendrik WESSELING in Molecular Autism, (July 2014)  

Public ISBD [article]  inMolecular Autism > (July 2014) . - p.1-17 Titre : Integrative proteomic analysis of the NMDA NR1 knockdown mouse model reveals effects on central and peripheral pathways associated with schizophrenia and autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Hendrik WESSELING, Auteur ; Paul C. GUEST, Auteur ; Chi-Ming LEE, Auteur ; Erik HF WONG, Auteur ; Hassan RAHMOUNE, Auteur ; Sabine BAHN, Auteur Article en page(s) : p.1-17 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Over the last decade, the transgenic N-methyl-D-aspartate receptor (NMDAR) NR1-knockdown mouse (NR1neo?/?) has been investigated as a glutamate hypofunction model for schizophrenia. Recent research has now revealed that the model also recapitulates cognitive and negative symptoms in the continuum of other psychiatric diseases, particularly autism spectrum disorders (ASD). As previous studies have mostly focussed on behavioural readouts, a molecular characterisation of this model will help to identify novel biomarkers or potential drug targets. En ligne : http://dx.doi.org/10.1186/2040-2392-5-38 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276 [article] Integrative proteomic analysis of the NMDA NR1 knockdown mouse model reveals effects on central and peripheral pathways associated with schizophrenia and autism spectrum disorders [Texte imprimé et/ou numérique] / Hendrik WESSELING, Auteur ; Paul C. GUEST, Auteur ; Chi-Ming LEE, Auteur ; Erik HF WONG, Auteur ; Hassan RAHMOUNE, Auteur ; Sabine BAHN, Auteur . - p.1-17. Langues : Anglais (eng) in Molecular Autism > (July 2014) . - p.1-17 Index. décimale : PER Périodiques Résumé : Over the last decade, the transgenic N-methyl-D-aspartate receptor (NMDAR) NR1-knockdown mouse (NR1neo?/?) has been investigated as a glutamate hypofunction model for schizophrenia. Recent research has now revealed that the model also recapitulates cognitive and negative symptoms in the continuum of other psychiatric diseases, particularly autism spectrum disorders (ASD). As previous studies have mostly focussed on behavioural readouts, a molecular characterisation of this model will help to identify novel biomarkers or potential drug targets. En ligne : http://dx.doi.org/10.1186/2040-2392-5-38 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276

Functional autonomic nervous system profile in children with autism spectrum disorder / Azadeh KUSHKI in Molecular Autism, (July 2014)  

Public ISBD [article]  inMolecular Autism > (July 2014) . - p.1-10 Titre : Functional autonomic nervous system profile in children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Azadeh KUSHKI, Auteur ; Jessica BRIAN, Auteur ; Annie DUPUIS, Auteur ; Evdokia ANAGNOSTOU, Auteur Article en page(s) : p.1-10 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autonomic dysregulation has been recently reported as a feature of autism spectrum disorder (ASD). However, the nature of autonomic atypicalities in ASD remain largely unknown. The goal of this study was to characterize the cardiac autonomic profile of children with ASD across four domains affected in ASD (anxiety, attention, response inhibition, and social cognition), and suggested to be affected by autonomic dysregulation. En ligne : http://dx.doi.org/10.1186/2040-2392-5-39 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276 [article] Functional autonomic nervous system profile in children with autism spectrum disorder [Texte imprimé et/ou numérique] / Azadeh KUSHKI, Auteur ; Jessica BRIAN, Auteur ; Annie DUPUIS, Auteur ; Evdokia ANAGNOSTOU, Auteur . - p.1-10. Langues : Anglais (eng) in Molecular Autism > (July 2014) . - p.1-10 Index. décimale : PER Périodiques Résumé : Autonomic dysregulation has been recently reported as a feature of autism spectrum disorder (ASD). However, the nature of autonomic atypicalities in ASD remain largely unknown. The goal of this study was to characterize the cardiac autonomic profile of children with ASD across four domains affected in ASD (anxiety, attention, response inhibition, and social cognition), and suggested to be affected by autonomic dysregulation. En ligne : http://dx.doi.org/10.1186/2040-2392-5-39 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276

Serum microRNA profiles in children with autism / Mahesh MUNDALIL VASU in Molecular Autism, (July 2014)  

Public ISBD [article]  inMolecular Autism > (July 2014) . - p.1-9 Titre : Serum microRNA profiles in children with autism Type de document : Texte imprimé et/ou numérique Auteurs : Mahesh MUNDALIL VASU, Auteur ; Ayyappan ANITHA, Auteur ; Ismail THANSEEM, Auteur ; Katsuaki SUZUKI, Auteur ; Kohei YAMADA, Auteur ; Taro TAKAHASHI, Auteur ; Tomoyasu WAKUDA, Auteur ; Keiko IWATA, Auteur ; Masatsugu TSUJII, Auteur ; Toshirou SUGIYAMA, Auteur ; Norio MORI, Auteur Article en page(s) : p.1-9 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : As regulators of gene expression, microRNAs (miRNAs) play a key role in the transcriptional networks of the developing human brain. Circulating miRNAs in the serum and plasma are remarkably stable and are suggested to have promise as noninvasive biomarkers for neurological and neurodevelopmental disorders. We examined the serum expression profiles of neurologically relevant miRNAs in autism spectrum disorder (ASD), a complex neurodevelopmental disorder characterized by multiple deficits in communication, social interaction and behavior. En ligne : http://dx.doi.org/10.1186/2040-2392-5-40 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276 [article] Serum microRNA profiles in children with autism [Texte imprimé et/ou numérique] / Mahesh MUNDALIL VASU, Auteur ; Ayyappan ANITHA, Auteur ; Ismail THANSEEM, Auteur ; Katsuaki SUZUKI, Auteur ; Kohei YAMADA, Auteur ; Taro TAKAHASHI, Auteur ; Tomoyasu WAKUDA, Auteur ; Keiko IWATA, Auteur ; Masatsugu TSUJII, Auteur ; Toshirou SUGIYAMA, Auteur ; Norio MORI, Auteur . - p.1-9. Langues : Anglais (eng) in Molecular Autism > (July 2014) . - p.1-9 Index. décimale : PER Périodiques Résumé : As regulators of gene expression, microRNAs (miRNAs) play a key role in the transcriptional networks of the developing human brain. Circulating miRNAs in the serum and plasma are remarkably stable and are suggested to have promise as noninvasive biomarkers for neurological and neurodevelopmental disorders. We examined the serum expression profiles of neurologically relevant miRNAs in autism spectrum disorder (ASD), a complex neurodevelopmental disorder characterized by multiple deficits in communication, social interaction and behavior. En ligne : http://dx.doi.org/10.1186/2040-2392-5-40 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276

Proteomic analysis of post mortem brain tissue from autism patients: evidence for opposite changes in prefrontal cortex and cerebellum in synaptic connectivity-related proteins / Jantine A.C. BROEK in Molecular Autism, (July 2014)  

Public ISBD [article]  inMolecular Autism > (July 2014) . - p.1-8 Titre : Proteomic analysis of post mortem brain tissue from autism patients: evidence for opposite changes in prefrontal cortex and cerebellum in synaptic connectivity-related proteins Type de document : Texte imprimé et/ou numérique Auteurs : Jantine A.C. BROEK, Auteur ; Paul C. GUEST, Auteur ; Hassan RAHMOUNE, Auteur ; Sabine BAHN, Auteur Article en page(s) : p.1-8 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism is a neurodevelopmental disorder characterized by impaired language, communication and social skills. Although genetic studies have been carried out in this field, none of the genes identified have led to an explanation of the underlying causes. Here, we have investigated molecular alterations by proteomic profiling of post mortem brain samples from autism patients and controls. The analysis focussed on prefrontal cortex and cerebellum as previous studies have found that these two brain regions are structurally and functionally connected, and they have been implicated in autism. En ligne : http://dx.doi.org/10.1186/2040-2392-5-41 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276 [article] Proteomic analysis of post mortem brain tissue from autism patients: evidence for opposite changes in prefrontal cortex and cerebellum in synaptic connectivity-related proteins [Texte imprimé et/ou numérique] / Jantine A.C. BROEK, Auteur ; Paul C. GUEST, Auteur ; Hassan RAHMOUNE, Auteur ; Sabine BAHN, Auteur . - p.1-8. Langues : Anglais (eng) in Molecular Autism > (July 2014) . - p.1-8 Index. décimale : PER Périodiques Résumé : Autism is a neurodevelopmental disorder characterized by impaired language, communication and social skills. Although genetic studies have been carried out in this field, none of the genes identified have led to an explanation of the underlying causes. Here, we have investigated molecular alterations by proteomic profiling of post mortem brain samples from autism patients and controls. The analysis focussed on prefrontal cortex and cerebellum as previous studies have found that these two brain regions are structurally and functionally connected, and they have been implicated in autism. En ligne : http://dx.doi.org/10.1186/2040-2392-5-41 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276