[article]
Titre : |
Brief Report: Approaches to 31P-MRS in Awake, Non-Sedated Children with and without Autism Spectrum Disorder |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
Laura C. ERICKSON, Auteur ; Ashley A. SCOTT VAN ZEELAND, Auteur ; Gavin HAMILTON, Auteur ; Alan J. LINCOLN, Auteur ; Beatrice A. GOLOMB, Auteur |
Année de publication : |
2012 |
Article en page(s) : |
p.1120-1126 |
Langues : |
Anglais (eng) |
Mots-clés : |
Autism ASD Magnetic resonance Energetics Muscle Brain Awake |
Index. décimale : |
PER Périodiques |
Résumé : |
We piloted a suite of approaches aimed to facilitate a successful series of up to four brain and muscle 31Phosphorus-Magnetic Resonance Spectroscopy (31P-MRS) scans performed in one session in 12 awake, non-sedated subjects (ages 6–18), 6 with autism spectrum disorders (ASD) and 6 controls. We targeted advanced preparation, parental input, physical comfort, short scan protocols, allocation of extra time, and subject emotional support. 100% of subjects completed at least one brain scan and one leg muscle scan: 42 of 46 attempted scans were completed (91%), with failures dominated by exercise muscle scans (completed in 6/6 controls but 3/6 cases). One completed scan lacked usable data unrelated to subject/scan procedure (orthodonture affected a frontal brain scan). As a group, these methods provide a foundation for conduct and enhancement of future MR studies in pediatric subjects with ASD. |
En ligne : |
http://dx.doi.org/10.1007/s10803-011-1359-x |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=156 |
in Journal of Autism and Developmental Disorders > 42-6 (June 2012) . - p.1120-1126
[article] Brief Report: Approaches to 31P-MRS in Awake, Non-Sedated Children with and without Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Laura C. ERICKSON, Auteur ; Ashley A. SCOTT VAN ZEELAND, Auteur ; Gavin HAMILTON, Auteur ; Alan J. LINCOLN, Auteur ; Beatrice A. GOLOMB, Auteur . - 2012 . - p.1120-1126. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 42-6 (June 2012) . - p.1120-1126
Mots-clés : |
Autism ASD Magnetic resonance Energetics Muscle Brain Awake |
Index. décimale : |
PER Périodiques |
Résumé : |
We piloted a suite of approaches aimed to facilitate a successful series of up to four brain and muscle 31Phosphorus-Magnetic Resonance Spectroscopy (31P-MRS) scans performed in one session in 12 awake, non-sedated subjects (ages 6–18), 6 with autism spectrum disorders (ASD) and 6 controls. We targeted advanced preparation, parental input, physical comfort, short scan protocols, allocation of extra time, and subject emotional support. 100% of subjects completed at least one brain scan and one leg muscle scan: 42 of 46 attempted scans were completed (91%), with failures dominated by exercise muscle scans (completed in 6/6 controls but 3/6 cases). One completed scan lacked usable data unrelated to subject/scan procedure (orthodonture affected a frontal brain scan). As a group, these methods provide a foundation for conduct and enhancement of future MR studies in pediatric subjects with ASD. |
En ligne : |
http://dx.doi.org/10.1007/s10803-011-1359-x |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=156 |
|  |