Brief Report: Mediation of Treatment Effect in a Communication Intervention for Pre-School Children with Autism / Catherine ALDRED in Journal of Autism and Developmental Disorders, 42-3 (March 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-3 (March 2012) . - p.447-454 Titre : Brief Report: Mediation of Treatment Effect in a Communication Intervention for Pre-School Children with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Catherine ALDRED, Auteur ; Jonathan GREEN, Auteur ; Richard EMSLEY, Auteur ; Helen MCCONACHIE, Auteur Année de publication : 2012 Article en page(s) : p.447-454 Langues : Anglais (eng) Mots-clés : Pre-school child  Intervention trial  Parental synchrony  Mediation Index. décimale : PER Périodiques Résumé : Tests of mediation in treatment trials can illuminate processes of change and suggest causal influences in development. We conducted a mediation analysis of a previously published randomised controlled trial of parent-mediated communication-focused treatment for autism against ordinary care, with 28 children aged 2–5 years (Aldred et al. in J Child Psychol Psychiatr 45:1–11, 2004). The hypothesised mediating process, targeted by the intervention, was an increase in parental synchronous response within parent–child interaction. The results showed partial mediation, with change in synchrony accounting for 34% of the positive intervention effect on autism symptomatology (Autism Diagnostic Observation Schedule communication and social domain algorithm); the result was confirmed by bootstrap estimation. Improved parental synchronous response to child communication can alter short-term autism symptom outcome with targeted therapy. En ligne : http://dx.doi.org/10.1007/s10803-011-1248-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=152 [article] Brief Report: Mediation of Treatment Effect in a Communication Intervention for Pre-School Children with Autism [Texte imprimé et/ou numérique] / Catherine ALDRED, Auteur ; Jonathan GREEN, Auteur ; Richard EMSLEY, Auteur ; Helen MCCONACHIE, Auteur . - 2012 . - p.447-454. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-3 (March 2012) . - p.447-454 Mots-clés : Pre-school child  Intervention trial  Parental synchrony  Mediation Index. décimale : PER Périodiques Résumé : Tests of mediation in treatment trials can illuminate processes of change and suggest causal influences in development. We conducted a mediation analysis of a previously published randomised controlled trial of parent-mediated communication-focused treatment for autism against ordinary care, with 28 children aged 2–5 years (Aldred et al. in J Child Psychol Psychiatr 45:1–11, 2004). The hypothesised mediating process, targeted by the intervention, was an increase in parental synchronous response within parent–child interaction. The results showed partial mediation, with change in synchrony accounting for 34% of the positive intervention effect on autism symptomatology (Autism Diagnostic Observation Schedule communication and social domain algorithm); the result was confirmed by bootstrap estimation. Improved parental synchronous response to child communication can alter short-term autism symptom outcome with targeted therapy. En ligne : http://dx.doi.org/10.1007/s10803-011-1248-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=152

Research Reviews: Advances in methods for evaluating child and adolescent mental health interventions / Danielle EDWARDS ; Levente HORVATH ; Richard EMSLEY in Journal of Child Psychology and Psychiatry, 64-12 (December 2023)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 64-12 (December 2023) . - p.1765-1775 Titre : Research Reviews: Advances in methods for evaluating child and adolescent mental health interventions Type de document : Texte imprimé et/ou numérique Auteurs : Danielle EDWARDS, Auteur ; Levente HORVATH, Auteur ; Richard EMSLEY, Auteur Article en page(s) : p.1765-1775 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Backround The evidence base for interventions for child mental health and neurodevelopment is weak and the current capacity for rigorous evaluation limited. We describe some of the challenges that make this field particularly difficult and expensive for evaluation studies. Methods We describe and review the use of novel study designs and analysis methodology for their potential to improve this situation. Results While several novel designs appeared ill-suited to our field, systematic review found others that offered potential but had yet to be widely adopted, some not at all. Conclusions While funding is inevitably a constraint, we argue that improvements in the evidence base of both current and new treatments will only be achieved by the adoption of a number of these new technologies and study designs, the consistent application of rigorous constructive but demanding standards, and the engagement of the public, patients, clinical and research services to build a design, recruitment, and analysis infrastructure. En ligne : https://doi.org/10.1111/jcpp.13892 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] Research Reviews: Advances in methods for evaluating child and adolescent mental health interventions [Texte imprimé et/ou numérique] / Danielle EDWARDS, Auteur ; Levente HORVATH, Auteur ; Richard EMSLEY, Auteur . - p.1765-1775. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 64-12 (December 2023) . - p.1765-1775 Index. décimale : PER Périodiques Résumé : Backround The evidence base for interventions for child mental health and neurodevelopment is weak and the current capacity for rigorous evaluation limited. We describe some of the challenges that make this field particularly difficult and expensive for evaluation studies. Methods We describe and review the use of novel study designs and analysis methodology for their potential to improve this situation. Results While several novel designs appeared ill-suited to our field, systematic review found others that offered potential but had yet to be widely adopted, some not at all. Conclusions While funding is inevitably a constraint, we argue that improvements in the evidence base of both current and new treatments will only be achieved by the adoption of a number of these new technologies and study designs, the consistent application of rigorous constructive but demanding standards, and the engagement of the public, patients, clinical and research services to build a design, recruitment, and analysis infrastructure. En ligne : https://doi.org/10.1111/jcpp.13892 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

Restricted and Repetitive Behaviors in Autism Spectrum Disorders and Typical Development: Cross-Sectional and Longitudinal Comparisons / Clare HARROP in Journal of Autism and Developmental Disorders, 44-5 (May 2014)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 44-5 (May 2014) . - p.1207-1219 Titre : Restricted and Repetitive Behaviors in Autism Spectrum Disorders and Typical Development: Cross-Sectional and Longitudinal Comparisons Type de document : Texte imprimé et/ou numérique Auteurs : Clare HARROP, Auteur ; Helen MCCONACHIE, Auteur ; Richard EMSLEY, Auteur ; Kathy LEADBITTER, Auteur ; Jonathan GREEN, Auteur Année de publication : 2014 Article en page(s) : p.1207-1219 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Repetitive behaviors  Measurement longitudinal Index. décimale : PER Périodiques Résumé : Restricted and repetitive behaviors (RRBs) are characteristic of autism spectrum disorders (ASD). However, compared to social and communicative impairments, less is known about their development, trajectory and etiology. This study explored RRBs in young children with ASD matched to typically developing (TD) children on non-verbal development. RRBs were coded from direct observation at three time points within 13 months of development. Children with ASD displayed higher frequency and greater diversity of RRBs at all time points, however RRBs were not unique to ASD and evident in the TD control group albeit at a reduced frequency. RRBs did not correlate with social and communicative impairments in the ASD group, suggesting dissociation between these domains. En ligne : http://dx.doi.org/10.1007/s10803-013-1986-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=232 [article] Restricted and Repetitive Behaviors in Autism Spectrum Disorders and Typical Development: Cross-Sectional and Longitudinal Comparisons [Texte imprimé et/ou numérique] / Clare HARROP, Auteur ; Helen MCCONACHIE, Auteur ; Richard EMSLEY, Auteur ; Kathy LEADBITTER, Auteur ; Jonathan GREEN, Auteur . - 2014 . - p.1207-1219. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 44-5 (May 2014) . - p.1207-1219 Mots-clés : Autism spectrum disorder  Repetitive behaviors  Measurement longitudinal Index. décimale : PER Périodiques Résumé : Restricted and repetitive behaviors (RRBs) are characteristic of autism spectrum disorders (ASD). However, compared to social and communicative impairments, less is known about their development, trajectory and etiology. This study explored RRBs in young children with ASD matched to typically developing (TD) children on non-verbal development. RRBs were coded from direct observation at three time points within 13 months of development. Children with ASD displayed higher frequency and greater diversity of RRBs at all time points, however RRBs were not unique to ASD and evident in the TD control group albeit at a reduced frequency. RRBs did not correlate with social and communicative impairments in the ASD group, suggesting dissociation between these domains. En ligne : http://dx.doi.org/10.1007/s10803-013-1986-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=232

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