Long-term Cognitive and Behavioral Therapies, Combined with Augmentative Communication, are Related to Uncinate Fasciculus Integrity in Autism / Matteo PARDINI in Journal of Autism and Developmental Disorders, 42-4 (April 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-4 (April 2012) . - p.585-592 Titre : Long-term Cognitive and Behavioral Therapies, Combined with Augmentative Communication, are Related to Uncinate Fasciculus Integrity in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Matteo PARDINI, Auteur ; Maurizio ELIA, Auteur ; Francesco GARACI, Auteur ; Silvia GUIDA, Auteur ; Filadelfo CONIGLIONE, Auteur ; Frank KRUEGER, Auteur ; Francesca BENASSI, Auteur ; Leonardo EMBERTI GIALLORETI, Auteur Année de publication : 2012 Article en page(s) : p.585-592 Langues : Anglais (eng) Mots-clés : Diffusion Tensor Imaging  Autism  Uncinate fasciculus  Cognitive therapy  Long-term rehabilitation Index. décimale : PER Périodiques Résumé : Recent evidence points to white-matter abnormalities as a key factor in autism physiopathology. Using Diffusion Tensor Imaging, we studied white-matter structural properties in a convenience sample of twenty-two subjects with low-functioning autism exposed to long-term augmentative and alternative communication, combined with sessions of cognitive and behavioral therapy. Uncinate fasciculus structural properties correlated significantly with therapy length and early onset, as well as to clinical outcome, independently from IQ, age or symptoms severity at therapy onset. Moreover, adherence to therapy was linked with better clinical outcome and uncinate fasciculus structural integrity. The results point to the capability of a long-term rehabilitation of subjects with low-functioning autism to produce white-matter structural modifications, which could thus play a role in the rehabilitative outcome. En ligne : http://dx.doi.org/10.1007/s10803-011-1281-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=153 [article] Long-term Cognitive and Behavioral Therapies, Combined with Augmentative Communication, are Related to Uncinate Fasciculus Integrity in Autism [Texte imprimé et/ou numérique] / Matteo PARDINI, Auteur ; Maurizio ELIA, Auteur ; Francesco GARACI, Auteur ; Silvia GUIDA, Auteur ; Filadelfo CONIGLIONE, Auteur ; Frank KRUEGER, Auteur ; Francesca BENASSI, Auteur ; Leonardo EMBERTI GIALLORETI, Auteur . - 2012 . - p.585-592. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-4 (April 2012) . - p.585-592 Mots-clés : Diffusion Tensor Imaging  Autism  Uncinate fasciculus  Cognitive therapy  Long-term rehabilitation Index. décimale : PER Périodiques Résumé : Recent evidence points to white-matter abnormalities as a key factor in autism physiopathology. Using Diffusion Tensor Imaging, we studied white-matter structural properties in a convenience sample of twenty-two subjects with low-functioning autism exposed to long-term augmentative and alternative communication, combined with sessions of cognitive and behavioral therapy. Uncinate fasciculus structural properties correlated significantly with therapy length and early onset, as well as to clinical outcome, independently from IQ, age or symptoms severity at therapy onset. Moreover, adherence to therapy was linked with better clinical outcome and uncinate fasciculus structural integrity. The results point to the capability of a long-term rehabilitation of subjects with low-functioning autism to produce white-matter structural modifications, which could thus play a role in the rehabilitative outcome. En ligne : http://dx.doi.org/10.1007/s10803-011-1281-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=153

Reduction in Retinal Nerve Fiber Layer Thickness in Young Adults with Autism Spectrum Disorders / Leonardo EMBERTI GIALLORETI in Journal of Autism and Developmental Disorders, 44-4 (April 2014)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 44-4 (April 2014) . - p.873-882 Titre : Reduction in Retinal Nerve Fiber Layer Thickness in Young Adults with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Leonardo EMBERTI GIALLORETI, Auteur ; Matteo PARDINI, Auteur ; Francesca BENASSI, Auteur ; Sara MARCIANO, Auteur ; Mario AMORE, Auteur ; Maria Giulia MUTOLO, Auteur ; Maria Cristina PORFIRIO, Auteur ; Paolo CURATOLO, Auteur Année de publication : 2014 Article en page(s) : p.873-882 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Retinal nerve fiber layer thickness  Optical coherence tomography (OCT)  White matter Index. décimale : PER Périodiques Résumé : Recent years have seen an increase in the use of retinal nerve fiber layer (RNFL) evaluation as an easy-to-use, reproducible, proxy-measure of brain structural abnormalities. Here, we evaluated RNFL thickness in a group of subjects with high functioning autism (HFA) or with Asperger Syndrome (AS) to its potential as a tool to study autism pathophysiology. All subjects underwent high-resolution spectral domain optical coherence tomography to evaluate RNFL thickness. HFA subjects presented with reduced global RNFL thickness compared both to AS subjects and controls. AS subjects showed a reduced nasal quadrant RNFL thickness compared to controls. Verbal-IQ/performance-IQ discrepancy correlated with RNFL thickness. Our data suggest that RNFL evaluation could help in the development of biological markers of autism pathophysiology. En ligne : http://dx.doi.org/10.1007/s10803-013-1939-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=228 [article] Reduction in Retinal Nerve Fiber Layer Thickness in Young Adults with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Leonardo EMBERTI GIALLORETI, Auteur ; Matteo PARDINI, Auteur ; Francesca BENASSI, Auteur ; Sara MARCIANO, Auteur ; Mario AMORE, Auteur ; Maria Giulia MUTOLO, Auteur ; Maria Cristina PORFIRIO, Auteur ; Paolo CURATOLO, Auteur . - 2014 . - p.873-882. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 44-4 (April 2014) . - p.873-882 Mots-clés : Autism spectrum disorders  Retinal nerve fiber layer thickness  Optical coherence tomography (OCT)  White matter Index. décimale : PER Périodiques Résumé : Recent years have seen an increase in the use of retinal nerve fiber layer (RNFL) evaluation as an easy-to-use, reproducible, proxy-measure of brain structural abnormalities. Here, we evaluated RNFL thickness in a group of subjects with high functioning autism (HFA) or with Asperger Syndrome (AS) to its potential as a tool to study autism pathophysiology. All subjects underwent high-resolution spectral domain optical coherence tomography to evaluate RNFL thickness. HFA subjects presented with reduced global RNFL thickness compared both to AS subjects and controls. AS subjects showed a reduced nasal quadrant RNFL thickness compared to controls. Verbal-IQ/performance-IQ discrepancy correlated with RNFL thickness. Our data suggest that RNFL evaluation could help in the development of biological markers of autism pathophysiology. En ligne : http://dx.doi.org/10.1007/s10803-013-1939-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=228

Response to the Letter to the Editor: Diffusion Tensor Imaging and Long-Term Therapies / Matteo PARDINI in Journal of Autism and Developmental Disorders, 43-2 (February 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-2 (February 2013) . - p.493-494 Titre : Response to the Letter to the Editor: Diffusion Tensor Imaging and Long-Term Therapies Type de document : Texte imprimé et/ou numérique Auteurs : Matteo PARDINI, Auteur ; Francesca BENASSI, Auteur ; Leonardo EMBERTI GIALLORETI, Auteur Article en page(s) : p.493-494 Langues : (Eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-012-1586-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=188 [article] Response to the Letter to the Editor: Diffusion Tensor Imaging and Long-Term Therapies [Texte imprimé et/ou numérique] / Matteo PARDINI, Auteur ; Francesca BENASSI, Auteur ; Leonardo EMBERTI GIALLORETI, Auteur . - p.493-494. Langues : (Eng) in Journal of Autism and Developmental Disorders > 43-2 (February 2013) . - p.493-494 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-012-1586-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=188

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