New Interview and Observation Measures of the Broader Autism Phenotype: Impressions of Interviewee Measure / A. PICKLES in Journal of Autism and Developmental Disorders, 43-9 (September 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-9 (September 2013) . - p.2082-2089 Titre : New Interview and Observation Measures of the Broader Autism Phenotype: Impressions of Interviewee Measure Type de document : Texte imprimé et/ou numérique Auteurs : A. PICKLES, Auteur ; Jeremy R. PARR, Auteur ; Michael L. RUTTER, Auteur ; M. V. JONGE, Auteur ; S. WALLACE, Auteur ; A. S. COUTEUR, Auteur ; Herman VAN ENGELAND, Auteur ; K. WITTEMEYER, Auteur ; H. MCCONACHIE, Auteur ; Bernadette ROGE, Auteur ; Carine MANTOULAN, Auteur ; L. PEDERSEN, Auteur ; T. ISAGER, Auteur ; F. POUSTKA, Auteur ; Sven BÖLTE, Auteur ; Patrick BOLTON, Auteur ; E. WEISBLATT, Auteur ; J. GREEN, Auteur ; Katerina PAPANIKOLAOU, Auteur ; A. J. BAILEY, Auteur Article en page(s) : p.2082-2089 Langues : Anglais (eng) Mots-clés : Broader autism phenotype  Observer rating  Test–retest  Factor analysis  Social functioning Index. décimale : PER Périodiques Résumé : A 20 item observational measure of social functioning, the Impression of Interviewee rating scale, is one of three measures devised to assess the broader autism phenotype. The sample studied included families containing at least two individuals with autism spectrum disorder; observations were undertaken by the researcher who interviewed the subject. An exploratory factor analysis suggested a single factor was most appropriate (Cronbach’s ? of 0.78). There was a modest but significant retest correlation of 0.42. Correlations between live ratings and blind consensus ratings of vignettes were high (0.93). Correlations with the interview measures were moderate but statistically significant. In conclusion, the observational scale provides a promising start but further work is required before general use can be recommended. En ligne : http://dx.doi.org/10.1007/s10803-013-1810-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212 [article] New Interview and Observation Measures of the Broader Autism Phenotype: Impressions of Interviewee Measure [Texte imprimé et/ou numérique] / A. PICKLES, Auteur ; Jeremy R. PARR, Auteur ; Michael L. RUTTER, Auteur ; M. V. JONGE, Auteur ; S. WALLACE, Auteur ; A. S. COUTEUR, Auteur ; Herman VAN ENGELAND, Auteur ; K. WITTEMEYER, Auteur ; H. MCCONACHIE, Auteur ; Bernadette ROGE, Auteur ; Carine MANTOULAN, Auteur ; L. PEDERSEN, Auteur ; T. ISAGER, Auteur ; F. POUSTKA, Auteur ; Sven BÖLTE, Auteur ; Patrick BOLTON, Auteur ; E. WEISBLATT, Auteur ; J. GREEN, Auteur ; Katerina PAPANIKOLAOU, Auteur ; A. J. BAILEY, Auteur . - p.2082-2089. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-9 (September 2013) . - p.2082-2089 Mots-clés : Broader autism phenotype  Observer rating  Test–retest  Factor analysis  Social functioning Index. décimale : PER Périodiques Résumé : A 20 item observational measure of social functioning, the Impression of Interviewee rating scale, is one of three measures devised to assess the broader autism phenotype. The sample studied included families containing at least two individuals with autism spectrum disorder; observations were undertaken by the researcher who interviewed the subject. An exploratory factor analysis suggested a single factor was most appropriate (Cronbach’s ? of 0.78). There was a modest but significant retest correlation of 0.42. Correlations between live ratings and blind consensus ratings of vignettes were high (0.93). Correlations with the interview measures were moderate but statistically significant. In conclusion, the observational scale provides a promising start but further work is required before general use can be recommended. En ligne : http://dx.doi.org/10.1007/s10803-013-1810-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212

Predictive Value of Morphological Features in Patients with Autism versus Normal Controls / Heval M. OZGEN in Journal of Autism and Developmental Disorders, 43-1 (January 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-1 (January 2013) . - p.147-155 Titre : Predictive Value of Morphological Features in Patients with Autism versus Normal Controls Type de document : Texte imprimé et/ou numérique Auteurs : Heval M. OZGEN, Auteur ; Gerhard S. HELLEMANN, Auteur ; M. V. JONGE, Auteur ; Frits A. BEEMER, Auteur ; Herman VAN ENGELAND, Auteur Article en page(s) : p.147-155 Langues : Anglais (eng) Mots-clés : Autism  Common variant  Endophenotype  Morphology  Minor anomaly  Predictive value  ROC  Recursive partitioning Index. décimale : PER Périodiques Résumé : We investigated the predictive power of morphological features in 224 autistic patients and 224 matched-pairs controls. To assess the relationship between the morphological features and autism, we used the receiver operator curves (ROC). In addition, we used recursive partitioning (RP) to determine a specific pattern of abnormalities that is characteristic for the difference between autistic children and typically developing controls. The present findings showed that morphological features are significantly increased in patients with autism. Using ROC and RP, some of the morphological measures also led to strong predictive accuracy. Facial asymmetry, multiple hair whorls and prominent forehead significantly differentiated patients with autism from controls. Future research on multivariable risk prediction models may benefit from the use of morphological features. En ligne : http://dx.doi.org/10.1007/s10803-012-1554-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=187 [article] Predictive Value of Morphological Features in Patients with Autism versus Normal Controls [Texte imprimé et/ou numérique] / Heval M. OZGEN, Auteur ; Gerhard S. HELLEMANN, Auteur ; M. V. JONGE, Auteur ; Frits A. BEEMER, Auteur ; Herman VAN ENGELAND, Auteur . - p.147-155. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-1 (January 2013) . - p.147-155 Mots-clés : Autism  Common variant  Endophenotype  Morphology  Minor anomaly  Predictive value  ROC  Recursive partitioning Index. décimale : PER Périodiques Résumé : We investigated the predictive power of morphological features in 224 autistic patients and 224 matched-pairs controls. To assess the relationship between the morphological features and autism, we used the receiver operator curves (ROC). In addition, we used recursive partitioning (RP) to determine a specific pattern of abnormalities that is characteristic for the difference between autistic children and typically developing controls. The present findings showed that morphological features are significantly increased in patients with autism. Using ROC and RP, some of the morphological measures also led to strong predictive accuracy. Facial asymmetry, multiple hair whorls and prominent forehead significantly differentiated patients with autism from controls. Future research on multivariable risk prediction models may benefit from the use of morphological features. En ligne : http://dx.doi.org/10.1007/s10803-012-1554-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=187

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