Aggressive behavior problems in children with autism spectrum disorders: Prevalence and correlates in a large clinical sample / Alison PRESMANES HILL in Research in Autism Spectrum Disorders, 8-9 (September 2014)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 8-9 (September 2014) . - p.1121-1133 Titre : Aggressive behavior problems in children with autism spectrum disorders: Prevalence and correlates in a large clinical sample Type de document : Texte imprimé et/ou numérique Auteurs : Alison PRESMANES HILL, Auteur ; Katharine E. ZUCKERMAN, Auteur ; Arlene D. HAGEN, Auteur ; Daniel J. KRIZ, Auteur ; Susanne W. DUVALL, Auteur ; Jan P. H. VAN SANTEN, Auteur ; Joel NIGG, Auteur ; Damien A. FAIR, Auteur ; Eric FOMBONNE, Auteur Article en page(s) : p.1121-1133 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Psychotropic drugs  Aggression  Sleep  Internalizing problems  Attention problems Index. décimale : PER Périodiques Résumé : Abstract Aggressive behavior problems (ABP) are frequent yet poorly understood in children with autism spectrum disorders (ASD) and are likely to co-vary significantly with comorbid problems. We examined the prevalence and sociodemographic correlates of ABP in a clinical sample of children with ASD (N = 400; 2–16.9 years). We also investigated whether children with ABP experience more intensive medical interventions, greater impairments in behavioral functioning, and more severe comorbid problems than children with ASD who do not have ABP. One in four children with ASD had Child Behavior Checklist scores on the Aggressive Behavior scale in the clinical range (T-scores ? 70). Sociodemographic factors (age, gender, parent education, race, ethnicity) were unrelated to ABP status. The presence of ABP was significantly associated with increased use of psychotropic drugs and melatonin, lower cognitive functioning, lower ASD severity, and greater comorbid sleep, internalizing, and attention problems. In multivariate models, sleep, internalizing, and attention problems were most strongly associated with ABP. These comorbid problems may hold promise as targets for treatment to decrease aggressive behavior and proactively identify high-risk profiles for prevention. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.05.006 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238 [article] Aggressive behavior problems in children with autism spectrum disorders: Prevalence and correlates in a large clinical sample [Texte imprimé et/ou numérique] / Alison PRESMANES HILL, Auteur ; Katharine E. ZUCKERMAN, Auteur ; Arlene D. HAGEN, Auteur ; Daniel J. KRIZ, Auteur ; Susanne W. DUVALL, Auteur ; Jan P. H. VAN SANTEN, Auteur ; Joel NIGG, Auteur ; Damien A. FAIR, Auteur ; Eric FOMBONNE, Auteur . - p.1121-1133. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 8-9 (September 2014) . - p.1121-1133 Mots-clés : Autism spectrum disorders  Psychotropic drugs  Aggression  Sleep  Internalizing problems  Attention problems Index. décimale : PER Périodiques Résumé : Abstract Aggressive behavior problems (ABP) are frequent yet poorly understood in children with autism spectrum disorders (ASD) and are likely to co-vary significantly with comorbid problems. We examined the prevalence and sociodemographic correlates of ABP in a clinical sample of children with ASD (N = 400; 2–16.9 years). We also investigated whether children with ABP experience more intensive medical interventions, greater impairments in behavioral functioning, and more severe comorbid problems than children with ASD who do not have ABP. One in four children with ASD had Child Behavior Checklist scores on the Aggressive Behavior scale in the clinical range (T-scores ? 70). Sociodemographic factors (age, gender, parent education, race, ethnicity) were unrelated to ABP status. The presence of ABP was significantly associated with increased use of psychotropic drugs and melatonin, lower cognitive functioning, lower ASD severity, and greater comorbid sleep, internalizing, and attention problems. In multivariate models, sleep, internalizing, and attention problems were most strongly associated with ABP. These comorbid problems may hold promise as targets for treatment to decrease aggressive behavior and proactively identify high-risk profiles for prevention. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.05.006 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238

Computational prosodic markers for autism / Jan P. H. VAN SANTEN in Autism, 14-3 (May 2010)  

Public ISBD [article]  inAutism > 14-3 (May 2010) . - p.215-236 Titre : Computational prosodic markers for autism Type de document : Texte imprimé et/ou numérique Auteurs : Jan P. H. VAN SANTEN, Auteur ; Lois M. BLACK, Auteur ; Emily T. PRUD'HOMMEAUX, Auteur ; Margaret MITCHELL, Auteur Année de publication : 2010 Article en page(s) : p.215-236 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : We present results obtained with new instrumental methods for the acoustic analysis of prosody to evaluate prosody production by children with Autism Spectrum Disorder (ASD) and Typical Development (TD). Two tasks elicit focal stress — one in a vocal imitation paradigm, the other in a picture-description paradigm; a third task also uses a vocal imitation paradigm, and requires repeating stress patterns of two-syllable nonsense words. The instrumental methods differentiated significantly between the ASD and TD groups in all but the focal stress imitation task. The methods also showed smaller differences in the two vocal imitation tasks than in the picture-description task, as was predicted. In fact, in the nonsense word stress repetition task, the instrumental methods showed better performance for the ASD group. The methods also revealed that the acoustic features that predict auditory-perceptual judgment are not the same as those that differentiate between groups. Specifically, a key difference between the groups appears to be a difference in the balance between the various prosodic cues, such as pitch, amplitude, and duration, and not necessarily a difference in the strength or clarity with which prosodic contrasts are expressed. En ligne : http://dx.doi.org/10.1177/1362361309363281 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107 [article] Computational prosodic markers for autism [Texte imprimé et/ou numérique] / Jan P. H. VAN SANTEN, Auteur ; Lois M. BLACK, Auteur ; Emily T. PRUD'HOMMEAUX, Auteur ; Margaret MITCHELL, Auteur . - 2010 . - p.215-236. Langues : Anglais (eng) in Autism > 14-3 (May 2010) . - p.215-236 Index. décimale : PER Périodiques Résumé : We present results obtained with new instrumental methods for the acoustic analysis of prosody to evaluate prosody production by children with Autism Spectrum Disorder (ASD) and Typical Development (TD). Two tasks elicit focal stress — one in a vocal imitation paradigm, the other in a picture-description paradigm; a third task also uses a vocal imitation paradigm, and requires repeating stress patterns of two-syllable nonsense words. The instrumental methods differentiated significantly between the ASD and TD groups in all but the focal stress imitation task. The methods also showed smaller differences in the two vocal imitation tasks than in the picture-description task, as was predicted. In fact, in the nonsense word stress repetition task, the instrumental methods showed better performance for the ASD group. The methods also revealed that the acoustic features that predict auditory-perceptual judgment are not the same as those that differentiate between groups. Specifically, a key difference between the groups appears to be a difference in the balance between the various prosodic cues, such as pitch, amplitude, and duration, and not necessarily a difference in the strength or clarity with which prosodic contrasts are expressed. En ligne : http://dx.doi.org/10.1177/1362361309363281 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=107

Memory in language-impaired children with and without autism / A. P. HILL in Journal of Neurodevelopmental Disorders, 7-1 (December 2015)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 7-1 (December 2015) . - p.19 Titre : Memory in language-impaired children with and without autism Type de document : Texte imprimé et/ou numérique Auteurs : A. P. HILL, Auteur ; Jan P. H. VAN SANTEN, Auteur ; K. GORMAN, Auteur ; B. H. LANGHORST, Auteur ; E. FOMBONNE, Auteur Article en page(s) : p.19 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Narrative  Nonword repetition  Processing speed  Specific language impairment  Verbal memory  Verbal working memory Index. décimale : PER Périodiques Résumé : BACKGROUND: A subgroup of young children with autism spectrum disorders (ASD) have significant language impairments (phonology, grammar, vocabulary), although such impairments are not considered to be core symptoms of and are not unique to ASD. Children with specific language impairment (SLI) display similar impairments in language. Given evidence for phenotypic and possibly etiologic overlap between SLI and ASD, it has been suggested that language-impaired children with ASD (ASD + language impairment, ALI) may be characterized as having both ASD and SLI. However, the extent to which the language phenotypes in SLI and ALI can be viewed as similar or different depends in part upon the age of the individuals studied. The purpose of the current study is to examine differences in memory abilities, specifically those that are key "markers" of heritable SLI, among young school-age children with SLI, ALI, and ALN (ASD + language normal). METHODS: In this cross-sectional study, three groups of children between ages 5 and 8 years participated: SLI (n = 18), ALI (n = 22), and ALN (n = 20). A battery of cognitive, language, and ASD assessments was administered as well as a nonword repetition (NWR) test and measures of verbal memory, visual memory, and processing speed. RESULTS: NWR difficulties were more severe in SLI than in ALI, with the largest effect sizes in response to nonwords with the shortest syllable lengths. Among children with ASD, NWR difficulties were not associated with the presence of impairments in multiple ASD domains, as reported previously. Verbal memory difficulties were present in both SLI and ALI groups relative to children with ALN. Performance on measures related to verbal but not visual memory or processing speed were significantly associated with the relative degree of language impairment in children with ASD, supporting the role of verbal memory difficulties in language impairments among early school-age children with ASD. CONCLUSIONS: The primary difference between children with SLI and ALI was in NWR performance, particularly in repeating two- and three-syllable nonwords, suggesting that shared difficulties in early language learning found in previous studies do not necessarily reflect the same underlying mechanisms. En ligne : http://dx.doi.org/10.1186/s11689-015-9111-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=347 [article] Memory in language-impaired children with and without autism [Texte imprimé et/ou numérique] / A. P. HILL, Auteur ; Jan P. H. VAN SANTEN, Auteur ; K. GORMAN, Auteur ; B. H. LANGHORST, Auteur ; E. FOMBONNE, Auteur . - p.19. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 7-1 (December 2015) . - p.19 Mots-clés : Autism spectrum disorders  Narrative  Nonword repetition  Processing speed  Specific language impairment  Verbal memory  Verbal working memory Index. décimale : PER Périodiques Résumé : BACKGROUND: A subgroup of young children with autism spectrum disorders (ASD) have significant language impairments (phonology, grammar, vocabulary), although such impairments are not considered to be core symptoms of and are not unique to ASD. Children with specific language impairment (SLI) display similar impairments in language. Given evidence for phenotypic and possibly etiologic overlap between SLI and ASD, it has been suggested that language-impaired children with ASD (ASD + language impairment, ALI) may be characterized as having both ASD and SLI. However, the extent to which the language phenotypes in SLI and ALI can be viewed as similar or different depends in part upon the age of the individuals studied. The purpose of the current study is to examine differences in memory abilities, specifically those that are key "markers" of heritable SLI, among young school-age children with SLI, ALI, and ALN (ASD + language normal). METHODS: In this cross-sectional study, three groups of children between ages 5 and 8 years participated: SLI (n = 18), ALI (n = 22), and ALN (n = 20). A battery of cognitive, language, and ASD assessments was administered as well as a nonword repetition (NWR) test and measures of verbal memory, visual memory, and processing speed. RESULTS: NWR difficulties were more severe in SLI than in ALI, with the largest effect sizes in response to nonwords with the shortest syllable lengths. Among children with ASD, NWR difficulties were not associated with the presence of impairments in multiple ASD domains, as reported previously. Verbal memory difficulties were present in both SLI and ALI groups relative to children with ALN. Performance on measures related to verbal but not visual memory or processing speed were significantly associated with the relative degree of language impairment in children with ASD, supporting the role of verbal memory difficulties in language impairments among early school-age children with ASD. CONCLUSIONS: The primary difference between children with SLI and ALI was in NWR performance, particularly in repeating two- and three-syllable nonwords, suggesting that shared difficulties in early language learning found in previous studies do not necessarily reflect the same underlying mechanisms. En ligne : http://dx.doi.org/10.1186/s11689-015-9111-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=347

Quantifying Repetitive Speech in Autism Spectrum Disorders and Language Impairment / Jan P. H. VAN SANTEN in Autism Research, 6-5 (October 2013)  

Public ISBD [article]  inAutism Research > 6-5 (October 2013) . - p.372-383 Titre : Quantifying Repetitive Speech in Autism Spectrum Disorders and Language Impairment Type de document : Texte imprimé et/ou numérique Auteurs : Jan P. H. VAN SANTEN, Auteur ; Richard W. SPROAT, Auteur ; Alison Presmanes HILL, Auteur Article en page(s) : p.372-383 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  specific language impairment  echolalia  repetitive behavior Index. décimale : PER Périodiques Résumé : We report on an automatic technique for quantifying two types of repetitive speech: repetitions of what the child says him/herself (self-repeats) and of what is uttered by an interlocutor (echolalia). We apply this technique to a sample of 111 children between the ages of four and eight: 42 typically developing children (TD), 19 children with specific language impairment (SLI), 25 children with autism spectrum disorders (ASD) plus language impairment (ALI), and 25 children with ASD with normal, non-impaired language (ALN). The results indicate robust differences in echolalia between the TD and ASD groups as a whole (ALN?+?ALI), and between TD and ALN children. There were no significant differences between ALI and SLI children for echolalia or self-repetitions. The results confirm previous findings that children with ASD repeat the language of others more than other populations of children. On the other hand, self-repetition does not appear to be significantly more frequent in ASD, nor does it matter whether the child's echolalia occurred within one (immediate) or two turns (near-immediate) of the adult's original utterance. Furthermore, non-significant differences between ALN and SLI, between TD and SLI, and between ALI and TD are suggestive that echolalia may not be specific to ALN or to ASD in general. One important innovation of this work is an objective fully automatic technique for assessing the amount of repetition in a transcript of a child's utterances En ligne : http://dx.doi.org/10.1002/aur.1301 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=218 [article] Quantifying Repetitive Speech in Autism Spectrum Disorders and Language Impairment [Texte imprimé et/ou numérique] / Jan P. H. VAN SANTEN, Auteur ; Richard W. SPROAT, Auteur ; Alison Presmanes HILL, Auteur . - p.372-383. Langues : Anglais (eng) in Autism Research > 6-5 (October 2013) . - p.372-383 Mots-clés : autism spectrum disorder  specific language impairment  echolalia  repetitive behavior Index. décimale : PER Périodiques Résumé : We report on an automatic technique for quantifying two types of repetitive speech: repetitions of what the child says him/herself (self-repeats) and of what is uttered by an interlocutor (echolalia). We apply this technique to a sample of 111 children between the ages of four and eight: 42 typically developing children (TD), 19 children with specific language impairment (SLI), 25 children with autism spectrum disorders (ASD) plus language impairment (ALI), and 25 children with ASD with normal, non-impaired language (ALN). The results indicate robust differences in echolalia between the TD and ASD groups as a whole (ALN?+?ALI), and between TD and ALN children. There were no significant differences between ALI and SLI children for echolalia or self-repetitions. The results confirm previous findings that children with ASD repeat the language of others more than other populations of children. On the other hand, self-repetition does not appear to be significantly more frequent in ASD, nor does it matter whether the child's echolalia occurred within one (immediate) or two turns (near-immediate) of the adult's original utterance. Furthermore, non-significant differences between ALN and SLI, between TD and SLI, and between ALI and TD are suggestive that echolalia may not be specific to ALN or to ASD in general. One important innovation of this work is an objective fully automatic technique for assessing the amount of repetition in a transcript of a child's utterances En ligne : http://dx.doi.org/10.1002/aur.1301 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=218

The Hypothesis of Apraxia of Speech in Children with Autism Spectrum Disorder / Lawrence D. SHRIBERG in Journal of Autism and Developmental Disorders, 41-4 (April 2011)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 41-4 (April 2011) . - p.405-426 Titre : The Hypothesis of Apraxia of Speech in Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Lawrence D. SHRIBERG, Auteur ; Rhea PAUL, Auteur ; Lois M. BLACK, Auteur ; Jan P. H. VAN SANTEN, Auteur Année de publication : 2011 Article en page(s) : p.405-426 Langues : Anglais (eng) Mots-clés : Apraxia  Dyspraxia  Motor speech disorder  Speech sound disorder Index. décimale : PER Périodiques Résumé : In a sample of 46 children aged 4–7 years with Autism Spectrum Disorder (ASD) and intelligible speech, there was no statistical support for the hypothesis of concomitant Childhood Apraxia of Speech (CAS). Perceptual and acoustic measures of participants’ speech, prosody, and voice were compared with data from 40 typically-developing children, 13 preschool children with Speech Delay, and 15 participants aged 5–49 years with CAS in neurogenetic disorders. Speech Delay and Speech Errors, respectively, were modestly and substantially more prevalent in participants with ASD than reported population estimates. Double dissociations in speech, prosody, and voice impairments in ASD were interpreted as consistent with a speech attunement framework, rather than with the motor speech impairments that define CAS. En ligne : http://dx.doi.org/10.1007/s10803-010-1117-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=119 [article] The Hypothesis of Apraxia of Speech in Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Lawrence D. SHRIBERG, Auteur ; Rhea PAUL, Auteur ; Lois M. BLACK, Auteur ; Jan P. H. VAN SANTEN, Auteur . - 2011 . - p.405-426. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 41-4 (April 2011) . - p.405-426 Mots-clés : Apraxia  Dyspraxia  Motor speech disorder  Speech sound disorder Index. décimale : PER Périodiques Résumé : In a sample of 46 children aged 4–7 years with Autism Spectrum Disorder (ASD) and intelligible speech, there was no statistical support for the hypothesis of concomitant Childhood Apraxia of Speech (CAS). Perceptual and acoustic measures of participants’ speech, prosody, and voice were compared with data from 40 typically-developing children, 13 preschool children with Speech Delay, and 15 participants aged 5–49 years with CAS in neurogenetic disorders. Speech Delay and Speech Errors, respectively, were modestly and substantially more prevalent in participants with ASD than reported population estimates. Double dissociations in speech, prosody, and voice impairments in ASD were interpreted as consistent with a speech attunement framework, rather than with the motor speech impairments that define CAS. En ligne : http://dx.doi.org/10.1007/s10803-010-1117-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=119

Uh and um in children with autism spectrum disorders or language impairment / Kyle GORMAN in Autism Research, 9-8 (August 2016)  

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