[article] 
inAutism Research > 8-3 (June 2015) . - p.250-260

Titre :	Exploring the Underdiagnosis and Prevalence of Autism Spectrum Conditions in Beijing
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Xiang SUN, Auteur ; Carrie ALLISON, Auteur ; Fiona E. MATTHEWS, Auteur ; Zhixiang ZHANG, Auteur ; Bonnie AUYEUNG, Auteur ; Simon BARON-COHEN, Auteur ; Carol BRAYNE, Auteur
Article en page(s) :	p.250-260
Langues :	Anglais (eng)
Mots-clés :	autism  prevalence  screening  diagnosis  CAST  China
Index. décimale :	PER Périodiques
Résumé :	Previous studies reported that the prevalence of Autism Spectrum Conditions (ASC) in mainland China is much lower than estimates from developed countries (around 1%). The aim of the study is to apply current screening and standardized diagnostic instruments to a Chinese population to establish a prevalence estimate of ASC in an undiagnosed population in mainland China. We followed the design development used previously in the UK published in 2009 by Baron-Cohen and colleagues. The Mandarin Childhood Autism Spectrum Test (CAST) was validated by screening primary school pupils (n?=?737 children age 6–10 years old) in Beijing and by conducting diagnostic assessments using the Autism Diagnostic Observation Schedule and the Autism Diagnostic Interview-Revised. The prevalence estimate was generated after adjusting and imputing for missing values using the inverse probability weighting. Response was high (97%). Using the UK cutoff (?15), CAST performance has 84% sensitivity and 96% specificity (95% confidence interval [CI]: 46, 98, and 96, 97, respectively). Six out of 103 children, not previously diagnosed, were found to the meet diagnostic criteria (8.5 after adjustment, 95% CI: 1.6, 15.4). The preliminary prevalence in an undiagnosed primary school population in mainland China was 119 per 10,000 (95% CI: 53, 265). The utility of CAST is acceptable as a screening instrument for ASC in large epidemiological studies in China. Using a comparable method, the preliminary prevalence estimate of ASC in mainland China is similar to that of those from developed countries.
En ligne :	http://dx.doi.org/10.1002/aur.1441
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=261

[article] Exploring the Underdiagnosis and Prevalence of Autism Spectrum Conditions in Beijing [Texte imprimé et/ou numérique] / Xiang SUN, Auteur ; Carrie ALLISON, Auteur ; Fiona E. MATTHEWS, Auteur ; Zhixiang ZHANG, Auteur ; Bonnie AUYEUNG, Auteur ; Simon BARON-COHEN, Auteur ; Carol BRAYNE, Auteur . - p.250-260.
Langues : Anglais (eng)
in Autism Research > 8-3 (June 2015) . - p.250-260

Mots-clés :	autism  prevalence  screening  diagnosis  CAST  China
Index. décimale :	PER Périodiques
Résumé :	Previous studies reported that the prevalence of Autism Spectrum Conditions (ASC) in mainland China is much lower than estimates from developed countries (around 1%). The aim of the study is to apply current screening and standardized diagnostic instruments to a Chinese population to establish a prevalence estimate of ASC in an undiagnosed population in mainland China. We followed the design development used previously in the UK published in 2009 by Baron-Cohen and colleagues. The Mandarin Childhood Autism Spectrum Test (CAST) was validated by screening primary school pupils (n?=?737 children age 6–10 years old) in Beijing and by conducting diagnostic assessments using the Autism Diagnostic Observation Schedule and the Autism Diagnostic Interview-Revised. The prevalence estimate was generated after adjusting and imputing for missing values using the inverse probability weighting. Response was high (97%). Using the UK cutoff (?15), CAST performance has 84% sensitivity and 96% specificity (95% confidence interval [CI]: 46, 98, and 96, 97, respectively). Six out of 103 children, not previously diagnosed, were found to the meet diagnostic criteria (8.5 after adjustment, 95% CI: 1.6, 15.4). The preliminary prevalence in an undiagnosed primary school population in mainland China was 119 per 10,000 (95% CI: 53, 265). The utility of CAST is acceptable as a screening instrument for ASC in large epidemiological studies in China. Using a comparable method, the preliminary prevalence estimate of ASC in mainland China is similar to that of those from developed countries.
En ligne :	http://dx.doi.org/10.1002/aur.1441
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=261