Age-Specific Time Trends in Incidence Rates of Autism Spectrum Disorder Following Adaptation of DSM-5 and Other ASD-Related Regulatory Changes in Israel / Michael DAVIDOVITCH in Autism Research, 13-11 (November 2020)  

Public ISBD [article]  inAutism Research > 13-11 (November 2020) . - p.1893-1901 Titre : Age-Specific Time Trends in Incidence Rates of Autism Spectrum Disorder Following Adaptation of DSM-5 and Other ASD-Related Regulatory Changes in Israel Type de document : Texte imprimé et/ou numérique Auteurs : Michael DAVIDOVITCH, Auteur ; Ortal SLOBODIN, Auteur ; Marc G. WEISSKOPF, Auteur ; Ran S. ROTEM, Auteur Article en page(s) : p.1893-1901 Langues : Anglais (eng) Mots-clés : Dsm  age trends  autism spectrum disorder  incidence  late diagnosis Index. décimale : PER Périodiques Résumé : We analyzed data on 879,029 children born in 1999-2017 from a large Israeli health fund to evaluate time-trends in incidence of autism spectrum disorder (ASD). This included examining possible effects associated with the adaptation of the DSM-5 criteria for ASD, and the implementation of regulatory changes affecting eligibility for ASD-related stipends and services. ASD cases were ascertained based on electronic medical records review, with complete verification of ASD case status. Results indicated a substantial increase in ASD incidence rate (IR) over time that was overall not appreciably affected by the above changes. Cumulative incidence through age 8 rose from 0.46% (boys: 0.73; girls: 0.18) in 2007 to 1.30% (boys: 2.12; girls: 0.45) in 2018. Age-specific analyzes indicated that the largest increase in IR occurred in toddlers and preschool children, with a more modest increase at older age groups. Results suggest that the rise in early diagnosed ASD does not stem from a downward shift in the distribution of ages at first diagnosis, but rather from early detection of cases not previously diagnosed. Findings highlight the need to expand research aimed at identifying exogenous factors that may underlie the rise in incidence, and to evaluate factors that may contribute to late diagnosis of some cases. Autism Res 2020, 13: 1893-1901. © 2020 International Society for Autism Research and Wiley Periodicals LLC LAY SUMMARY: In an analysis of nearly 900,000 Israeli children born in 1999-2017, we found that the incidence of autism spectrum disorder (ASD) increased significantly over time, especially among toddlers and preschool children but also at older age groups. We additionally observed that changes affecting diagnostic criteria for ASD and eligibility for ASD-related services did not appreciably affect these trends. Results highlight the need to continue research aimed at identifying factors causing this increase and reasons contributing to late diagnosis of some cases. En ligne : http://dx.doi.org/10.1002/aur.2420 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Age-Specific Time Trends in Incidence Rates of Autism Spectrum Disorder Following Adaptation of DSM-5 and Other ASD-Related Regulatory Changes in Israel [Texte imprimé et/ou numérique] / Michael DAVIDOVITCH, Auteur ; Ortal SLOBODIN, Auteur ; Marc G. WEISSKOPF, Auteur ; Ran S. ROTEM, Auteur . - p.1893-1901. Langues : Anglais (eng) in Autism Research > 13-11 (November 2020) . - p.1893-1901 Mots-clés : Dsm  age trends  autism spectrum disorder  incidence  late diagnosis Index. décimale : PER Périodiques Résumé : We analyzed data on 879,029 children born in 1999-2017 from a large Israeli health fund to evaluate time-trends in incidence of autism spectrum disorder (ASD). This included examining possible effects associated with the adaptation of the DSM-5 criteria for ASD, and the implementation of regulatory changes affecting eligibility for ASD-related stipends and services. ASD cases were ascertained based on electronic medical records review, with complete verification of ASD case status. Results indicated a substantial increase in ASD incidence rate (IR) over time that was overall not appreciably affected by the above changes. Cumulative incidence through age 8 rose from 0.46% (boys: 0.73; girls: 0.18) in 2007 to 1.30% (boys: 2.12; girls: 0.45) in 2018. Age-specific analyzes indicated that the largest increase in IR occurred in toddlers and preschool children, with a more modest increase at older age groups. Results suggest that the rise in early diagnosed ASD does not stem from a downward shift in the distribution of ages at first diagnosis, but rather from early detection of cases not previously diagnosed. Findings highlight the need to expand research aimed at identifying exogenous factors that may underlie the rise in incidence, and to evaluate factors that may contribute to late diagnosis of some cases. Autism Res 2020, 13: 1893-1901. © 2020 International Society for Autism Research and Wiley Periodicals LLC LAY SUMMARY: In an analysis of nearly 900,000 Israeli children born in 1999-2017, we found that the incidence of autism spectrum disorder (ASD) increased significantly over time, especially among toddlers and preschool children but also at older age groups. We additionally observed that changes affecting diagnostic criteria for ASD and eligibility for ASD-related services did not appreciably affect these trends. Results highlight the need to continue research aimed at identifying factors causing this increase and reasons contributing to late diagnosis of some cases. En ligne : http://dx.doi.org/10.1002/aur.2420 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

An Examination of Family Transmission of Traits Measured by the Social Responsiveness Scale-Short Form / Anna V. OPPENHEIMER in Journal of Autism and Developmental Disorders, 54-11 (November)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 54-11 (November) . - p.4034-4044 Titre : An Examination of Family Transmission of Traits Measured by the Social Responsiveness Scale-Short Form Type de document : Texte imprimé et/ou numérique Auteurs : Anna V. OPPENHEIMER, Auteur ; Marc G. WEISSKOPF, Auteur ; Kristen LYALL, Auteur Article en page(s) : p.4034-4044 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The Social Responsiveness Scale (SRS) is frequently used in research settings to measure characteristics associated with autism spectrum disorders (ASD). A short version has been developed but not yet tested for certain properties of the full SRS, such as familiality. The purpose of this study was to determine if prior familiality findings for the full SRS can be replicated using the short form by measuring the associations of the parental Social Responsiveness Scale-Short Form (SRS-SF) scores with child ASD diagnoses and child SRS-SF scores. En ligne : https://doi.org/10.1007/s10803-023-06115-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=536 [article] An Examination of Family Transmission of Traits Measured by the Social Responsiveness Scale-Short Form [Texte imprimé et/ou numérique] / Anna V. OPPENHEIMER, Auteur ; Marc G. WEISSKOPF, Auteur ; Kristen LYALL, Auteur . - p.4034-4044. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 54-11 (November) . - p.4034-4044 Index. décimale : PER Périodiques Résumé : The Social Responsiveness Scale (SRS) is frequently used in research settings to measure characteristics associated with autism spectrum disorders (ASD). A short version has been developed but not yet tested for certain properties of the full SRS, such as familiality. The purpose of this study was to determine if prior familiality findings for the full SRS can be replicated using the short form by measuring the associations of the parental Social Responsiveness Scale-Short Form (SRS-SF) scores with child ASD diagnoses and child SRS-SF scores. En ligne : https://doi.org/10.1007/s10803-023-06115-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=536

Differences in Autism Spectrum Disorders Incidence by Sub-Populations in Israel 1992–2009: A Total Population Study / Raanan RAZ in Journal of Autism and Developmental Disorders, 45-4 (April 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-4 (April 2015) . - p.1062-1069 Titre : Differences in Autism Spectrum Disorders Incidence by Sub-Populations in Israel 1992–2009: A Total Population Study Type de document : Texte imprimé et/ou numérique Auteurs : Raanan RAZ, Auteur ; Marc G. WEISSKOPF, Auteur ; Michael DAVIDOVITCH, Auteur ; Ofir PINTO, Auteur ; Hagai LEVINE, Auteur Article en page(s) : p.1062-1069 Langues : Anglais (eng) Mots-clés : Autism  Incidence  Prevalence  Israel  Sub-populations Index. décimale : PER Périodiques Résumé : We analyzed data from the Israeli National Insurance Institute (NII). Autism Spectrum Disorder (ASD) incidence was calculated for all children born in Israel 1992–2009, and by population groups. Overall, 9,109 ASD cases among 2,431,649 children were identified. ASD cumulative incidence by age 8 years increased 10-fold during 2000–2011, from 0.49 % to 0.49 %, while other child disabilities in NII increased only 1.65-fold. There was a consistent increase in ASD incidence with advancing birth cohorts born 1992–2004, stabilizing among those born 2005–2009. ASD rates among Israeli Arabs were substantially lower, and increased about 10 years later than the general population. The findings suggest a role for ASD awareness, accessing of the government benefit, or the way the concept of ASD is perceived. En ligne : http://dx.doi.org/10.1007/s10803-014-2262-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Differences in Autism Spectrum Disorders Incidence by Sub-Populations in Israel 1992–2009: A Total Population Study [Texte imprimé et/ou numérique] / Raanan RAZ, Auteur ; Marc G. WEISSKOPF, Auteur ; Michael DAVIDOVITCH, Auteur ; Ofir PINTO, Auteur ; Hagai LEVINE, Auteur . - p.1062-1069. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-4 (April 2015) . - p.1062-1069 Mots-clés : Autism  Incidence  Prevalence  Israel  Sub-populations Index. décimale : PER Périodiques Résumé : We analyzed data from the Israeli National Insurance Institute (NII). Autism Spectrum Disorder (ASD) incidence was calculated for all children born in Israel 1992–2009, and by population groups. Overall, 9,109 ASD cases among 2,431,649 children were identified. ASD cumulative incidence by age 8 years increased 10-fold during 2000–2011, from 0.49 % to 0.49 %, while other child disabilities in NII increased only 1.65-fold. There was a consistent increase in ASD incidence with advancing birth cohorts born 1992–2004, stabilizing among those born 2005–2009. ASD rates among Israeli Arabs were substantially lower, and increased about 10 years later than the general population. The findings suggest a role for ASD awareness, accessing of the government benefit, or the way the concept of ASD is perceived. En ligne : http://dx.doi.org/10.1007/s10803-014-2262-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Incidence time trends and socioeconomic factors in the observed incidence of autism spectrum disorder in israel: A nationwide nested case-control study / A. SEGEV in Autism Research, 12-12 (December)  

Public ISBD [article]  inAutism Research > 12-12 (December) . - p.1870-1879 Titre : Incidence time trends and socioeconomic factors in the observed incidence of autism spectrum disorder in israel: A nationwide nested case-control study Type de document : Texte imprimé et/ou numérique Auteurs : A. SEGEV, Auteur ; Marc G. WEISSKOPF, Auteur ; H. LEVINE, Auteur ; O. PINTO, Auteur ; R. RAZ, Auteur Année de publication : 2019 Article en page(s) : p.1870-1879 Langues : Anglais (eng) Mots-clés : Israel  autism spectrum disorder  incidence  socioeconomic factors Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) trends have been gaining a great deal of focus in recent decades, as many studies worldwide show a continued rise in incidence rates. Many researchers have begun analyzing socioeconomic data in relation to ASD in an effort to understand the source of these changing rates and the role of awareness and access to resources. In this study, we aim to contribute to this body of knowledge by examining incidence time trends of ASD in Israel according to socioeconomic factors. While similar studies have been conducted in Israel, this study is the first of its kind to include the total population. Individual-level data from the Israeli National Insurance Institute were used to determine cumulative incidence of ASD, first for the total population, and then stratified by population group and income categories. Multivariable logistic regression models were fit to analyze associations between income category and both risk of ASD and risk of ASD diagnosis in later age. A total of 431,348 children were examined in this study, with 13,841 cases of ASD. The cumulative incidence of all children aged 8 in 2015 was 0.64%, marking an increase compared to previous literature from Israel. Within our study period, ASD incidence followed this increase until the 2009 birth cohort, where it began to stabilize. Our initial findings from regression models showed strong positive associations between household income and ASD incidence, as expected. After factoring in population group, however, the elevated ASD incidence rates in the highest income bracket decreased. Autism Res 2019, 12: 1870-1879. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This study contributes comprehensive and current data on ASD trends overtime in Israel and introduces crucial insights regarding the impact of socioeconomic factors on ASD diagnoses. We found a rise in ASD that began leveling off in 2009. We identified more ASD diagnoses occurring in families with higher incomes and in the General Population, pointing to the important role of sociodemographic factors on ASD diagnoses. En ligne : http://dx.doi.org/10.1002/aur.2185 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 [article] Incidence time trends and socioeconomic factors in the observed incidence of autism spectrum disorder in israel: A nationwide nested case-control study [Texte imprimé et/ou numérique] / A. SEGEV, Auteur ; Marc G. WEISSKOPF, Auteur ; H. LEVINE, Auteur ; O. PINTO, Auteur ; R. RAZ, Auteur . - 2019 . - p.1870-1879. Langues : Anglais (eng) in Autism Research > 12-12 (December) . - p.1870-1879 Mots-clés : Israel  autism spectrum disorder  incidence  socioeconomic factors Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) trends have been gaining a great deal of focus in recent decades, as many studies worldwide show a continued rise in incidence rates. Many researchers have begun analyzing socioeconomic data in relation to ASD in an effort to understand the source of these changing rates and the role of awareness and access to resources. In this study, we aim to contribute to this body of knowledge by examining incidence time trends of ASD in Israel according to socioeconomic factors. While similar studies have been conducted in Israel, this study is the first of its kind to include the total population. Individual-level data from the Israeli National Insurance Institute were used to determine cumulative incidence of ASD, first for the total population, and then stratified by population group and income categories. Multivariable logistic regression models were fit to analyze associations between income category and both risk of ASD and risk of ASD diagnosis in later age. A total of 431,348 children were examined in this study, with 13,841 cases of ASD. The cumulative incidence of all children aged 8 in 2015 was 0.64%, marking an increase compared to previous literature from Israel. Within our study period, ASD incidence followed this increase until the 2009 birth cohort, where it began to stabilize. Our initial findings from regression models showed strong positive associations between household income and ASD incidence, as expected. After factoring in population group, however, the elevated ASD incidence rates in the highest income bracket decreased. Autism Res 2019, 12: 1870-1879. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This study contributes comprehensive and current data on ASD trends overtime in Israel and introduces crucial insights regarding the impact of socioeconomic factors on ASD diagnoses. We found a rise in ASD that began leveling off in 2009. We identified more ASD diagnoses occurring in families with higher incomes and in the General Population, pointing to the important role of sociodemographic factors on ASD diagnoses. En ligne : http://dx.doi.org/10.1002/aur.2185 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413

Maternal Exposure to Childhood Abuse is Associated with Mate Selection: Implications for Autism in Offspring / Andrea L. ROBERTS in Journal of Autism and Developmental Disorders, 47-7 (July 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-7 (July 2017) . - p.1998-2009 Titre : Maternal Exposure to Childhood Abuse is Associated with Mate Selection: Implications for Autism in Offspring Type de document : Texte imprimé et/ou numérique Auteurs : Andrea L. ROBERTS, Auteur ; Kristen LYALL, Auteur ; Marc G. WEISSKOPF, Auteur Article en page(s) : p.1998-2009 Langues : Anglais (eng) Mots-clés : Childhood abuse  Maternal factors  Paternal factors  Genetics  Mate selection  Autism Index. décimale : PER Périodiques Résumé : Maternal experience of childhood abuse has been associated with offspring autism. To explore whether familial tendency towards autistic traits—presumably related to genetic predisposition—accounts for this association, we examined whether women who experienced childhood abuse were more likely to select mates with high levels of autistic traits, and whether parental autistic traits accounted for the association of maternal abuse and offspring autism in 209 autism cases and 833 controls. Maternal childhood abuse was strongly associated with high paternal autistic traits (severe abuse, OR = 3.98, 95% CI = 1.26, 8.31). Maternal and paternal autistic traits accounted for 21% of the association between maternal abuse and offspring autism. These results provide evidence that childhood abuse affects mate selection, with implications for offspring health. En ligne : https://doi.org/10.1007/s10803-017-3115-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=313 [article] Maternal Exposure to Childhood Abuse is Associated with Mate Selection: Implications for Autism in Offspring [Texte imprimé et/ou numérique] / Andrea L. ROBERTS, Auteur ; Kristen LYALL, Auteur ; Marc G. WEISSKOPF, Auteur . - p.1998-2009. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-7 (July 2017) . - p.1998-2009 Mots-clés : Childhood abuse  Maternal factors  Paternal factors  Genetics  Mate selection  Autism Index. décimale : PER Périodiques Résumé : Maternal experience of childhood abuse has been associated with offspring autism. To explore whether familial tendency towards autistic traits—presumably related to genetic predisposition—accounts for this association, we examined whether women who experienced childhood abuse were more likely to select mates with high levels of autistic traits, and whether parental autistic traits accounted for the association of maternal abuse and offspring autism in 209 autism cases and 833 controls. Maternal childhood abuse was strongly associated with high paternal autistic traits (severe abuse, OR = 3.98, 95% CI = 1.26, 8.31). Maternal and paternal autistic traits accounted for 21% of the association between maternal abuse and offspring autism. These results provide evidence that childhood abuse affects mate selection, with implications for offspring health. En ligne : https://doi.org/10.1007/s10803-017-3115-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=313

Maternal exposure to intimate partner abuse before birth is associated with autism spectrum disorder in offspring / Andrea L. ROBERTS in Autism, 20-1 (January 2016)  

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Women's posttraumatic stress symptoms and autism spectrum disorder in their children / Andrea L. ROBERTS in Research in Autism Spectrum Disorders, 8-6 (June 2014)  

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