Predicting childhood effortful control from interactions between early parenting quality and children's dopamine transporter gene haplotypes / Yi LI in Development and Psychopathology, 28-1 (February 2016)  

Public ISBD [article]  inDevelopment and Psychopathology > 28-1 (February 2016) . - p.199-212 Titre : Predicting childhood effortful control from interactions between early parenting quality and children's dopamine transporter gene haplotypes Type de document : Texte imprimé et/ou numérique Auteurs : Yi LI, Auteur ; Michael J. SULIK, Auteur ; Nancy EISENBERG, Auteur ; Tracy L. SPINRAD, Auteur ; Kathryn LEMERY-CHALFANT, Auteur ; Daryn A. STOVER, Auteur ; Brian C. VERRELLI, Auteur Article en page(s) : p.199-212 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Children's observed effortful control (EC) at 30, 42, and 54 months (n = 145) was predicted from the interaction between mothers' observed parenting with their 30-month-olds and three variants of the solute carrier family C6, member 3 (SLC6A3) dopamine transporter gene (single nucleotide polymorphisms in intron8 and intron13, and a 40 base pair variable number tandem repeat [VNTR] in the 3?-untranslated region [UTR]), as well as haplotypes of these variants. Significant moderating effects were found. Children without the intron8-A/intron13-G, intron8-A/3?-UTR VNTR-10, or intron13-G/3?-UTR VNTR-10 haplotypes (i.e., haplotypes associated with the reduced SLC6A3 gene expression and thus lower dopamine functioning) appeared to demonstrate altered levels of EC as a function of maternal parenting quality, whereas children with these haplotypes demonstrated a similar EC level regardless of the parenting quality. Children with these haplotypes demonstrated a trade-off, such that they showed higher EC, relative to their counterparts without these haplotypes, when exposed to less supportive maternal parenting. The findings revealed a diathesis–stress pattern and suggested that different SLC6A3 haplotypes, but not single variants, might represent different levels of young children's sensitivity/responsivity to early parenting. En ligne : http://dx.doi.org/10.1017/S0954579415000383 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 [article] Predicting childhood effortful control from interactions between early parenting quality and children's dopamine transporter gene haplotypes [Texte imprimé et/ou numérique] / Yi LI, Auteur ; Michael J. SULIK, Auteur ; Nancy EISENBERG, Auteur ; Tracy L. SPINRAD, Auteur ; Kathryn LEMERY-CHALFANT, Auteur ; Daryn A. STOVER, Auteur ; Brian C. VERRELLI, Auteur . - p.199-212. Langues : Anglais (eng) in Development and Psychopathology > 28-1 (February 2016) . - p.199-212 Index. décimale : PER Périodiques Résumé : Children's observed effortful control (EC) at 30, 42, and 54 months (n = 145) was predicted from the interaction between mothers' observed parenting with their 30-month-olds and three variants of the solute carrier family C6, member 3 (SLC6A3) dopamine transporter gene (single nucleotide polymorphisms in intron8 and intron13, and a 40 base pair variable number tandem repeat [VNTR] in the 3?-untranslated region [UTR]), as well as haplotypes of these variants. Significant moderating effects were found. Children without the intron8-A/intron13-G, intron8-A/3?-UTR VNTR-10, or intron13-G/3?-UTR VNTR-10 haplotypes (i.e., haplotypes associated with the reduced SLC6A3 gene expression and thus lower dopamine functioning) appeared to demonstrate altered levels of EC as a function of maternal parenting quality, whereas children with these haplotypes demonstrated a similar EC level regardless of the parenting quality. Children with these haplotypes demonstrated a trade-off, such that they showed higher EC, relative to their counterparts without these haplotypes, when exposed to less supportive maternal parenting. The findings revealed a diathesis–stress pattern and suggested that different SLC6A3 haplotypes, but not single variants, might represent different levels of young children's sensitivity/responsivity to early parenting. En ligne : http://dx.doi.org/10.1017/S0954579415000383 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278

Prenatal exposure to hypoxic risk conditions in autistic and neurotypical youth: Associated ventricular differences, sleep disturbance, and sensory processing / Cristian PRECIADO in Autism Research, 17-12 (December 2024)  

Public ISBD [article]  inAutism Research > 17-12 (December 2024) . - p.2547-2557 Titre : Prenatal exposure to hypoxic risk conditions in autistic and neurotypical youth: Associated ventricular differences, sleep disturbance, and sensory processing Type de document : Texte imprimé et/ou numérique Auteurs : Cristian PRECIADO, Auteur ; Maria BAIDA, Auteur ; Yi LI, Auteur ; Yan LI, Auteur ; Carly DEMOPOULOS, Auteur Article en page(s) : p.2547-2557 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  freesurfer  neurodevelopment  prenatal hypoxia  sensory processing  sleep disturbance  thalamus  third ventricle Index. décimale : PER Périodiques Résumé : Abstract There is a growing body of research that suggests conditions during the period of pregnancy and birth can affect how autism spectrum disorder (ASD) presents itself. This study aimed to investigate the incidence of oxygen deprivation during this period known as prenatal and perinatal hypoxic risk (HR) conditions in ASD compared with neurotypical control (NTC) youth. We also examined ventricular morphology variations associated with HR exposure, and to evaluate associations with clinical symptoms. Results from a cohort of 104 youth revealed a higher incidence of exposure to prenatal hypoxic conditions in the ASD group. Additionally, ASD individuals with prenatal hypoxic exposure (ASD?+?HR) demonstrated larger third ventricle volumes compared with both ASD and NTC individuals without such exposure (ASD-HR and NTC-HR, respectively). Furthermore, associations were identified between prenatal hypoxic exposure, third ventricle volume, sensory dysfunction, and severity of sleep disturbances. These findings suggest exposure to prenatal hypoxic risk conditions may exacerbate or modify the neurodevelopmental trajectory and symptom severity in ASD, emphasizing the need for better prenatal care and specific interventions to reduce these risks. En ligne : https://dx.doi.org/10.1002/aur.3250 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=544 [article] Prenatal exposure to hypoxic risk conditions in autistic and neurotypical youth: Associated ventricular differences, sleep disturbance, and sensory processing [Texte imprimé et/ou numérique] / Cristian PRECIADO, Auteur ; Maria BAIDA, Auteur ; Yi LI, Auteur ; Yan LI, Auteur ; Carly DEMOPOULOS, Auteur . - p.2547-2557. Langues : Anglais (eng) in Autism Research > 17-12 (December 2024) . - p.2547-2557 Mots-clés : autism spectrum disorder  freesurfer  neurodevelopment  prenatal hypoxia  sensory processing  sleep disturbance  thalamus  third ventricle Index. décimale : PER Périodiques Résumé : Abstract There is a growing body of research that suggests conditions during the period of pregnancy and birth can affect how autism spectrum disorder (ASD) presents itself. This study aimed to investigate the incidence of oxygen deprivation during this period known as prenatal and perinatal hypoxic risk (HR) conditions in ASD compared with neurotypical control (NTC) youth. We also examined ventricular morphology variations associated with HR exposure, and to evaluate associations with clinical symptoms. Results from a cohort of 104 youth revealed a higher incidence of exposure to prenatal hypoxic conditions in the ASD group. Additionally, ASD individuals with prenatal hypoxic exposure (ASD?+?HR) demonstrated larger third ventricle volumes compared with both ASD and NTC individuals without such exposure (ASD-HR and NTC-HR, respectively). Furthermore, associations were identified between prenatal hypoxic exposure, third ventricle volume, sensory dysfunction, and severity of sleep disturbances. These findings suggest exposure to prenatal hypoxic risk conditions may exacerbate or modify the neurodevelopmental trajectory and symptom severity in ASD, emphasizing the need for better prenatal care and specific interventions to reduce these risks. En ligne : https://dx.doi.org/10.1002/aur.3250 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=544

Virtual reality with psychophysiological monitoring as an approach to evaluate emotional reactivity, social skills, and joint attention in autism spectrum disorder / Estate M. SOKHADZE

Public ISBD in Autism imaging and Devices / Manuel F. CASANOVA Titre : Virtual reality with psychophysiological monitoring as an approach to evaluate emotional reactivity, social skills, and joint attention in autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Estate M. SOKHADZE, Auteur ; Manuel F. CASANOVA, Auteur ; Desmond L. KELLY, Auteur ; Guela E. SOKHADZE, Auteur ; Yi LI, Auteur ; Adel S. ELMAGHRABY, Auteur ; Ayman S. EL-BAZ, Auteur Importance : p.371-396 Langues : Anglais (eng) Index. décimale : SCI-D SCI-D - Neurosciences Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=382 in Autism imaging and Devices / Manuel F. CASANOVA Virtual reality with psychophysiological monitoring as an approach to evaluate emotional reactivity, social skills, and joint attention in autism spectrum disorder [Texte imprimé et/ou numérique] / Estate M. SOKHADZE, Auteur ; Manuel F. CASANOVA, Auteur ; Desmond L. KELLY, Auteur ; Guela E. SOKHADZE, Auteur ; Yi LI, Auteur ; Adel S. ELMAGHRABY, Auteur ; Ayman S. EL-BAZ, Auteur . - [s.d.] . - p.371-396. Langues : Anglais (eng) Index. décimale : SCI-D SCI-D - Neurosciences Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=382

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