Neural responses to monetary incentives among self-injuring adolescent girls / Colin L. SAUDER in Development and Psychopathology, 28-1 (February 2016)  

Public ISBD [article]  inDevelopment and Psychopathology > 28-1 (February 2016) . - p.277-291 Titre : Neural responses to monetary incentives among self-injuring adolescent girls Type de document : Texte imprimé et/ou numérique Auteurs : Colin L. SAUDER, Auteur ; Christina M. DERBIDGE, Auteur ; Theodore P. BEAUCHAINE, Auteur Article en page(s) : p.277-291 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Rates of self-inflicted injury among adolescents have risen in recent years, yet much remains to be learned about the pathophysiology of such conduct. Self-injuring adolescents report high levels of both impulsivity and depression behaviorally. Aberrant neural responding to incentives, particularly in striatal and prefrontal regions, is observed among both impulsive and depressed adolescents, and may mark common vulnerability to symptoms of anhedonia, irritability, and low positive affectivity. To date, however, no studies have examined associations between central nervous system reward responding and self-injury. In the current study, self-injuring (n = 19) and control (n = 19) adolescent females, ages 13–19 years, participated in a monetary incentive delay task in which rewards were obtained on some trials and losses were incurred on others. Consistent with previous findings from impulsive and depressed samples, self-injuring adolescents exhibited less activation in both striatal and orbitofrontal cortex regions during anticipation of reward than did controls. Self-injuring adolescents also exhibited reduced bilateral amygdala activation during reward anticipation. Although few studies to date have examined amygdala activity during reward tasks, such findings are common among adults with mood disorders and borderline personality disorder. Implications for neural models of impulsivity, depression, heterotypic comorbidity, and development of both self-injury and borderline personality traits are discussed. En ligne : http://dx.doi.org/10.1017/S0954579415000449 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 [article] Neural responses to monetary incentives among self-injuring adolescent girls [Texte imprimé et/ou numérique] / Colin L. SAUDER, Auteur ; Christina M. DERBIDGE, Auteur ; Theodore P. BEAUCHAINE, Auteur . - p.277-291. Langues : Anglais (eng) in Development and Psychopathology > 28-1 (February 2016) . - p.277-291 Index. décimale : PER Périodiques Résumé : Rates of self-inflicted injury among adolescents have risen in recent years, yet much remains to be learned about the pathophysiology of such conduct. Self-injuring adolescents report high levels of both impulsivity and depression behaviorally. Aberrant neural responding to incentives, particularly in striatal and prefrontal regions, is observed among both impulsive and depressed adolescents, and may mark common vulnerability to symptoms of anhedonia, irritability, and low positive affectivity. To date, however, no studies have examined associations between central nervous system reward responding and self-injury. In the current study, self-injuring (n = 19) and control (n = 19) adolescent females, ages 13–19 years, participated in a monetary incentive delay task in which rewards were obtained on some trials and losses were incurred on others. Consistent with previous findings from impulsive and depressed samples, self-injuring adolescents exhibited less activation in both striatal and orbitofrontal cortex regions during anticipation of reward than did controls. Self-injuring adolescents also exhibited reduced bilateral amygdala activation during reward anticipation. Although few studies to date have examined amygdala activity during reward tasks, such findings are common among adults with mood disorders and borderline personality disorder. Implications for neural models of impulsivity, depression, heterotypic comorbidity, and development of both self-injury and borderline personality traits are discussed. En ligne : http://dx.doi.org/10.1017/S0954579415000449 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278

Neural responses to monetary incentives among self-injuring adolescent girls—CORRIGENDUM / Colin L. SAUDER in Development and Psychopathology, 30-4 (October 2018)  

Public ISBD [article]  inDevelopment and Psychopathology > 30-4 (October 2018) . - p.1543-1543 Titre : Neural responses to monetary incentives among self-injuring adolescent girls—CORRIGENDUM Type de document : Texte imprimé et/ou numérique Auteurs : Colin L. SAUDER, Auteur ; Christina M. DERBIDGE, Auteur ; Theodore P. BEAUCHAINE, Auteur Article en page(s) : p.1543-1543 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579417001869 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 [article] Neural responses to monetary incentives among self-injuring adolescent girls—CORRIGENDUM [Texte imprimé et/ou numérique] / Colin L. SAUDER, Auteur ; Christina M. DERBIDGE, Auteur ; Theodore P. BEAUCHAINE, Auteur . - p.1543-1543. Langues : Anglais (eng) in Development and Psychopathology > 30-4 (October 2018) . - p.1543-1543 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/S0954579417001869 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368

Self-injuring adolescent girls exhibit insular cortex volumetric abnormalities that are similar to those seen in adults with borderline personality disorder / Theodore P. BEAUCHAINE in Development and Psychopathology, 31-4 (October 2019)  

Public ISBD [article]  inDevelopment and Psychopathology > 31-4 (October 2019) . - p.1203-1212 Titre : Self-injuring adolescent girls exhibit insular cortex volumetric abnormalities that are similar to those seen in adults with borderline personality disorder Type de document : Texte imprimé et/ou numérique Auteurs : Theodore P. BEAUCHAINE, Auteur ; Colin L. SAUDER, Auteur ; Christina M. DERBIDGE, Auteur ; L. L. UYEJI, Auteur Article en page(s) : p.1203-1212 Langues : Anglais (eng) Mots-clés : adolescence  borderline personality disorder  insula  magnetic resonance imaging  self-injury Index. décimale : PER Périodiques Résumé : Self-inflicted injury (SII) in adolescence is a serious public health concern that portends prospective vulnerability to internalizing and externalizing psychopathology, borderline personality development, suicide attempts, and suicide. To date, however, our understanding of neurobiological vulnerabilities to SII is limited. Behaviorally, affect dysregulation is common among those who self-injure. This suggests ineffective cortical modulation of emotion, as observed among adults with borderline personality disorder. In borderline samples, structural and functional abnormalities are observed in several frontal regions that subserve emotion regulation (e.g., anterior cingulate, insula, dorsolateral prefrontal cortex). However, no volumetric analyses of cortical brain regions have been conducted among self-injuring adolescents. We used voxel-based morphometry to compare cortical gray matter volumes between self-injuring adolescent girls, ages 13-19 years (n = 20), and controls (n = 20). Whole-brain analyses revealed reduced gray matter volumes among self-injurers in the insular cortex bilaterally, and in the right inferior frontal gyrus, an adjacent neural structure also implicated in emotion and self-regulation. Insular and inferior frontal gyrus gray matter volumes correlated inversely with self-reported emotion dysregulation, over-and-above effects of psychopathology. Findings are consistent with an emotion dysregulation construal of SII, and indicate structural abnormalities in some but not all cortical brain regions implicated in borderline personality disorder among adults. En ligne : http://dx.doi.org/10.1017/s0954579418000822 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=406 [article] Self-injuring adolescent girls exhibit insular cortex volumetric abnormalities that are similar to those seen in adults with borderline personality disorder [Texte imprimé et/ou numérique] / Theodore P. BEAUCHAINE, Auteur ; Colin L. SAUDER, Auteur ; Christina M. DERBIDGE, Auteur ; L. L. UYEJI, Auteur . - p.1203-1212. Langues : Anglais (eng) in Development and Psychopathology > 31-4 (October 2019) . - p.1203-1212 Mots-clés : adolescence  borderline personality disorder  insula  magnetic resonance imaging  self-injury Index. décimale : PER Périodiques Résumé : Self-inflicted injury (SII) in adolescence is a serious public health concern that portends prospective vulnerability to internalizing and externalizing psychopathology, borderline personality development, suicide attempts, and suicide. To date, however, our understanding of neurobiological vulnerabilities to SII is limited. Behaviorally, affect dysregulation is common among those who self-injure. This suggests ineffective cortical modulation of emotion, as observed among adults with borderline personality disorder. In borderline samples, structural and functional abnormalities are observed in several frontal regions that subserve emotion regulation (e.g., anterior cingulate, insula, dorsolateral prefrontal cortex). However, no volumetric analyses of cortical brain regions have been conducted among self-injuring adolescents. We used voxel-based morphometry to compare cortical gray matter volumes between self-injuring adolescent girls, ages 13-19 years (n = 20), and controls (n = 20). Whole-brain analyses revealed reduced gray matter volumes among self-injurers in the insular cortex bilaterally, and in the right inferior frontal gyrus, an adjacent neural structure also implicated in emotion and self-regulation. Insular and inferior frontal gyrus gray matter volumes correlated inversely with self-reported emotion dysregulation, over-and-above effects of psychopathology. Findings are consistent with an emotion dysregulation construal of SII, and indicate structural abnormalities in some but not all cortical brain regions implicated in borderline personality disorder among adults. En ligne : http://dx.doi.org/10.1017/s0954579418000822 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=406

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