[article]
| Titre : |
Anxiety disorders in children with williams syndrome, their mothers, and their siblings: implications for the etiology of anxiety disorders |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
O. LEYFER, Auteur ; J. WOODRUFF-BORDEN, Auteur ; C. B. MERVIS, Auteur |
| Article en page(s) : |
p.4-14 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Anxiety Family Genetics Intellectual disability Mental retardation Williams syndrome |
| Index. décimale : |
PER Périodiques |
| Résumé : |
PURPOSE: To determine the prevalence of anxiety disorders in children with Williams syndrome (WS), their sibling closest in age, and their mothers and to examine the predictors of anxiety in these groups. METHODS: The prevalence of anxiety disorders was assessed and compared to that in the general population. RESULTS: Children with WS had a significantly higher prevalence of specific phobia, generalized anxiety disorder (GAD), and separation anxiety in comparison to children in the general population. While mothers had a higher prevalence of GAD than population controls, the excess was accounted for by mothers who had onset after the birth of their WS child. The siblings had rates similar to the general population. CONCLUSIONS: This pattern of findings suggests the presence of a gene in the WS region whose deletion predisposes to anxiety disorders. It is also worthwhile to investigate relations between genes deleted in WS and genes previously implicated in anxiety disorders. |
| En ligne : |
http://dx.doi.org/10.1007/s11689-009-9003-1 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=341 |
in Journal of Neurodevelopmental Disorders > 1-1 (March 2009) . - p.4-14
[article] Anxiety disorders in children with williams syndrome, their mothers, and their siblings: implications for the etiology of anxiety disorders [Texte imprimé et/ou numérique] / O. LEYFER, Auteur ; J. WOODRUFF-BORDEN, Auteur ; C. B. MERVIS, Auteur . - p.4-14. Langues : Anglais ( eng) in Journal of Neurodevelopmental Disorders > 1-1 (March 2009) . - p.4-14
| Mots-clés : |
Anxiety Family Genetics Intellectual disability Mental retardation Williams syndrome |
| Index. décimale : |
PER Périodiques |
| Résumé : |
PURPOSE: To determine the prevalence of anxiety disorders in children with Williams syndrome (WS), their sibling closest in age, and their mothers and to examine the predictors of anxiety in these groups. METHODS: The prevalence of anxiety disorders was assessed and compared to that in the general population. RESULTS: Children with WS had a significantly higher prevalence of specific phobia, generalized anxiety disorder (GAD), and separation anxiety in comparison to children in the general population. While mothers had a higher prevalence of GAD than population controls, the excess was accounted for by mothers who had onset after the birth of their WS child. The siblings had rates similar to the general population. CONCLUSIONS: This pattern of findings suggests the presence of a gene in the WS region whose deletion predisposes to anxiety disorders. It is also worthwhile to investigate relations between genes deleted in WS and genes previously implicated in anxiety disorders. |
| En ligne : |
http://dx.doi.org/10.1007/s11689-009-9003-1 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=341 |
|
Anxiety disorders in children with williams syndrome, their mothers, and their siblings: implications for the etiology of anxiety disorders in Journal of Neurodevelopmental Disorders, 1-1 (March 2009)
