Bone Density in Adolescents and Young Adults with Autism Spectrum Disorders / Laya EKHLASPOUR in Journal of Autism and Developmental Disorders, 46-11 (November 2016)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 46-11 (November 2016) . - p.3387-3391 Titre : Bone Density in Adolescents and Young Adults with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Laya EKHLASPOUR, Auteur ; Charumathi BASKARAN, Auteur ; Karen Joanie CAMPOVERDE, Auteur ; Natalia Cano SOKOLOFF, Auteur ; Ann M. NEUMEYER, Auteur ; Madhusmita MISRA, Auteur Article en page(s) : p.3387-3391 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Bone mineral density  Adolescent  Dual energy X-ray absorptiometry  Body mass index Index. décimale : PER Périodiques Résumé : Patients with autism spectrum disorder (ASD) are at increased risk for fracture, and peri-pubertal boys with ASD have lower bone mineral density (BMD) than controls. Data are lacking regarding BMD in older adolescents with ASD. We compared BMD using dual-energy X-ray absorptiometry in 9 adolescents/young adults with ASD against 9 typically developing matched controls. Patients with ASD and controls were excluded if they had other underlying conditions that may affect bone. Compared to controls, patients with ASD had (i) lower femoral neck and hip BMD Z-scores, and (ii) lower spine, femoral neck and hip height adjusted BMD Z-scores even after controlling for BMI. Understanding the underlying pathophysiology will be key to developing therapies to improve BMD and reduce fracture risk. En ligne : http://dx.doi.org/10.1007/s10803-016-2871-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=293 [article] Bone Density in Adolescents and Young Adults with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Laya EKHLASPOUR, Auteur ; Charumathi BASKARAN, Auteur ; Karen Joanie CAMPOVERDE, Auteur ; Natalia Cano SOKOLOFF, Auteur ; Ann M. NEUMEYER, Auteur ; Madhusmita MISRA, Auteur . - p.3387-3391. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-11 (November 2016) . - p.3387-3391 Mots-clés : Autism spectrum disorder  Bone mineral density  Adolescent  Dual energy X-ray absorptiometry  Body mass index Index. décimale : PER Périodiques Résumé : Patients with autism spectrum disorder (ASD) are at increased risk for fracture, and peri-pubertal boys with ASD have lower bone mineral density (BMD) than controls. Data are lacking regarding BMD in older adolescents with ASD. We compared BMD using dual-energy X-ray absorptiometry in 9 adolescents/young adults with ASD against 9 typically developing matched controls. Patients with ASD and controls were excluded if they had other underlying conditions that may affect bone. Compared to controls, patients with ASD had (i) lower femoral neck and hip BMD Z-scores, and (ii) lower spine, femoral neck and hip height adjusted BMD Z-scores even after controlling for BMI. Understanding the underlying pathophysiology will be key to developing therapies to improve BMD and reduce fracture risk. En ligne : http://dx.doi.org/10.1007/s10803-016-2871-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=293

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