Editorial: Supporting families in the first 1,000 days of life – a balancing act / Maartje P. C. M. LUIJK in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1445-1448 Titre : Editorial: Supporting families in the first 1,000 days of life – a balancing act Type de document : texte imprimé Auteurs : Maartje P. C. M. LUIJK, Auteur ; Tessa J. ROSEBOOM, Auteur Article en page(s) : p.1445-1448 Langues : Anglais (eng) Mots-clés : Early-life experiences  parenting  infancy  social policy  child development Index. décimale : PER Périodiques Résumé : From the moment of fertilization, human development takes a phenomenal pace. In no other period of life are more biological and developmental milestones met than in the first 1,000 days after conception. All organs and systems are formed, and children start to discover the world, learn whom to trust and where to find comfort in times of distress. Evidence from biological, psychological, social and economic research shows that the environment in the first 1,000 days significantly impacts a person's ability to reach their full potential. Children who grow up in unpredictable and unsafe environments often struggle with the consequences for the rest of their lives. Investments in this critical period of human development have proven to be the most cost-effective way to improve lifelong health and well-being. Therefore, this period has gained interest both in political debate and society at large. In this contribution, we demonstrate that while the focus on the first 1,000 days is scientifically sound and historically grounded, it is time to reflect on its societal impact. We focus on its unintended negative consequences for parental well-being. Evidence for the importance of the first 1,000 days should drive collective action rather than reinforce individual blame. Parenting is not just a private matter; governments have a duty to provide parents with the resources to give their children the best start in life. En ligne : https://doi.org/10.1111/jcpp.70041 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Editorial: Supporting families in the first 1,000 days of life – a balancing act [texte imprimé] / Maartje P. C. M. LUIJK, Auteur ; Tessa J. ROSEBOOM, Auteur . - p.1445-1448. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1445-1448 Mots-clés : Early-life experiences  parenting  infancy  social policy  child development Index. décimale : PER Périodiques Résumé : From the moment of fertilization, human development takes a phenomenal pace. In no other period of life are more biological and developmental milestones met than in the first 1,000 days after conception. All organs and systems are formed, and children start to discover the world, learn whom to trust and where to find comfort in times of distress. Evidence from biological, psychological, social and economic research shows that the environment in the first 1,000 days significantly impacts a person's ability to reach their full potential. Children who grow up in unpredictable and unsafe environments often struggle with the consequences for the rest of their lives. Investments in this critical period of human development have proven to be the most cost-effective way to improve lifelong health and well-being. Therefore, this period has gained interest both in political debate and society at large. In this contribution, we demonstrate that while the focus on the first 1,000 days is scientifically sound and historically grounded, it is time to reflect on its societal impact. We focus on its unintended negative consequences for parental well-being. Evidence for the importance of the first 1,000 days should drive collective action rather than reinforce individual blame. Parenting is not just a private matter; governments have a duty to provide parents with the resources to give their children the best start in life. En ligne : https://doi.org/10.1111/jcpp.70041 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Methylation matters: FK506 binding protein 51 (FKBP5) methylation moderates the associations of FKBP5 genotype and resistant attachment with stress regulation / Rosa H. MULDER in Development and Psychopathology, 29-2 (May 2017)  

Public ISBD [article]  inDevelopment and Psychopathology > 29-2 (May 2017) . - p.491-503 Titre : Methylation matters: FK506 binding protein 51 (FKBP5) methylation moderates the associations of FKBP5 genotype and resistant attachment with stress regulation Type de document : texte imprimé Auteurs : Rosa H. MULDER, Auteur ; Jolien RIJLAARSDAM, Auteur ; Maartje P. C. M. LUIJK, Auteur ; Frank C. VERHULST, Auteur ; Janine F. FELIX, Auteur ; Henning TIEMEIER, Auteur ; Marian J. BAKERMANS-KRANENBURG, Auteur ; Marinus H. VAN IJZENDOORN, Auteur Article en page(s) : p.491-503 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The parent–child attachment relationship plays an important role in the development of the infant's stress regulation system. However, genetic and epigenetic factors such as FK506 binding protein 51 (FKBP5) genotype and DNA methylation have also been associated with hypothalamus–pituitary–adrenal axis functioning. In the current study, we examined how parent–child dyadic regulation works in concert with genetic and epigenetic aspects of stress regulation. We study the associations of attachment, extreme maternal insensitivity, FKBP5 single nucleotide polymorphism 1360780, and FKBP5 methylation, with cortisol reactivity to the Strange Situation Procedure in 298 14-month-old infants. The results indicate that FKBP5 methylation moderates the associations of FKBP5 genotype and resistant attachment with cortisol reactivity. We conclude that the inclusion of epigenetics in the field of developmental psychopathology may lead to a more precise picture of the interplay between genetic makeup and parenting in shaping stress reactivity. En ligne : http://dx.doi.org/10.1017/s095457941700013x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305 [article] Methylation matters: FK506 binding protein 51 (FKBP5) methylation moderates the associations of FKBP5 genotype and resistant attachment with stress regulation [texte imprimé] / Rosa H. MULDER, Auteur ; Jolien RIJLAARSDAM, Auteur ; Maartje P. C. M. LUIJK, Auteur ; Frank C. VERHULST, Auteur ; Janine F. FELIX, Auteur ; Henning TIEMEIER, Auteur ; Marian J. BAKERMANS-KRANENBURG, Auteur ; Marinus H. VAN IJZENDOORN, Auteur . - p.491-503. Langues : Anglais (eng) in Development and Psychopathology > 29-2 (May 2017) . - p.491-503 Index. décimale : PER Périodiques Résumé : The parent–child attachment relationship plays an important role in the development of the infant's stress regulation system. However, genetic and epigenetic factors such as FK506 binding protein 51 (FKBP5) genotype and DNA methylation have also been associated with hypothalamus–pituitary–adrenal axis functioning. In the current study, we examined how parent–child dyadic regulation works in concert with genetic and epigenetic aspects of stress regulation. We study the associations of attachment, extreme maternal insensitivity, FKBP5 single nucleotide polymorphism 1360780, and FKBP5 methylation, with cortisol reactivity to the Strange Situation Procedure in 298 14-month-old infants. The results indicate that FKBP5 methylation moderates the associations of FKBP5 genotype and resistant attachment with cortisol reactivity. We conclude that the inclusion of epigenetics in the field of developmental psychopathology may lead to a more precise picture of the interplay between genetic makeup and parenting in shaping stress reactivity. En ligne : http://dx.doi.org/10.1017/s095457941700013x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305

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