[article]
Titre : |
Brief Report: Maternal Opioid Prescription from Preconception Through Pregnancy and the Odds of Autism Spectrum Disorder and Autism Features in Children |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
E. RUBENSTEIN, Auteur ; J. C. YOUNG, Auteur ; Lisa A. CROEN, Auteur ; Carolyn G. DIGUISEPPI, Auteur ; N. F. DOWLING, Auteur ; L. C. LEE, Auteur ; Laura A. SCHIEVE, Auteur ; Lisa D. WIGGINS, Auteur ; J. DANIELS, Auteur |
Article en page(s) : |
p.376-382 |
Langues : |
Anglais (eng) |
Mots-clés : |
Asd Developmental disorder Opioid Pregnancy Risk factor |
Index. décimale : |
PER Périodiques |
Résumé : |
Opioid use during pregnancy is associated with suboptimal pregnancy outcomes. Little is known about child neurodevelopmental outcomes. We examined associations between maternal opioid prescriptions preconception to delivery (peri-pregnancy) and child's risk of ASD, developmental delay/disorder (DD) with no ASD features, or ASD/DD with autism features in the Study to Explore Early Development, a case-control study of neurodevelopment. Preconception opioid prescription was associated with 2.43 times the odds of ASD [95% confidence interval (CI) 0.99, 6.02] and 2.64 times the odds of ASD/DD with autism features (95% CI 1.10, 6.31) compared to mothers without prescriptions. Odds for ASD and ASD/DD were non-significantly elevated for first trimester prescriptions. Work exploring mechanisms and timing between peri-pregnancy opioid use and child neurodevelopment is needed. |
En ligne : |
http://dx.doi.org/10.1007/s10803-018-3721-8 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=377 |
in Journal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.376-382
[article] Brief Report: Maternal Opioid Prescription from Preconception Through Pregnancy and the Odds of Autism Spectrum Disorder and Autism Features in Children [Texte imprimé et/ou numérique] / E. RUBENSTEIN, Auteur ; J. C. YOUNG, Auteur ; Lisa A. CROEN, Auteur ; Carolyn G. DIGUISEPPI, Auteur ; N. F. DOWLING, Auteur ; L. C. LEE, Auteur ; Laura A. SCHIEVE, Auteur ; Lisa D. WIGGINS, Auteur ; J. DANIELS, Auteur . - p.376-382. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.376-382
Mots-clés : |
Asd Developmental disorder Opioid Pregnancy Risk factor |
Index. décimale : |
PER Périodiques |
Résumé : |
Opioid use during pregnancy is associated with suboptimal pregnancy outcomes. Little is known about child neurodevelopmental outcomes. We examined associations between maternal opioid prescriptions preconception to delivery (peri-pregnancy) and child's risk of ASD, developmental delay/disorder (DD) with no ASD features, or ASD/DD with autism features in the Study to Explore Early Development, a case-control study of neurodevelopment. Preconception opioid prescription was associated with 2.43 times the odds of ASD [95% confidence interval (CI) 0.99, 6.02] and 2.64 times the odds of ASD/DD with autism features (95% CI 1.10, 6.31) compared to mothers without prescriptions. Odds for ASD and ASD/DD were non-significantly elevated for first trimester prescriptions. Work exploring mechanisms and timing between peri-pregnancy opioid use and child neurodevelopment is needed. |
En ligne : |
http://dx.doi.org/10.1007/s10803-018-3721-8 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=377 |
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